醫師介紹

Doctor Introduction

:::

醫師個人介紹

Chih-Yuan Ko
Chih-Yuan Ko

主治醫師

柯智淵 Chih-Yuan Ko

主治醫師
柯智淵醫師為中華民國關節重建醫學會會員,專長為微創型人工關節置換手術(髖關節及膝關節)及關節注射治療。近年來更鑽研電腦輔助保膝手術、保髖手術、退化性關節炎細胞治療技術及骨折畸型矯正手術。
分院掛號
學術論文

期刊論文

期刊論文/Journal Paper
(作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄)
日期
1 柯智淵(Chih-Yuan KO)、蔡俊灝(Chun-Hao Tsai)、馮逸卿(Yi-Ching Fong)、陳潓誼(Hui-Yi Chen)、陳賢德(Hsien-Te Chen)、林宗立(Tsung-Li Lin)*,Effect of Surgeon Volume on Mechanical Complications after Resection Arthroplasty with Articulating Spacer,Journal of Personalized Medicine,2024 May,14(490):1-15 2024 . 05
2 Achudhan Dav(Achudhan David)、賴宇亮(Yu-Liang Lai)、林彥佑、(Yuan-Li Huang)、蔡俊灝(Chun-Hao Tsai)、Ho Trung Loc(HO TRUNG LOC)、柯智淵(Chih-Yuan KO)、馮逸卿(Yi-Ching Fong)、黃建中(Huang, Chien-Chung)*、湯智昕(Chih-Hsin Tang)*,CXCL13 promotes TNF-α synthesis in rheumatoid arthritis through activating ERK/p38 pathway and inhibiting miR-330-3p generation,BIOCHEMICAL PHARMACOLOGY,2024 Mar,221():1-10 2024 . 03
3 (Chih-Yang Lin)、(Kun-Tsan Lee)、林彥佑、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、馮逸卿(Yi-Ching Fong)、(Sheng-Mou Hou)、(Wei-Li Chen)、黃建中(Huang, Chien-Chung)、湯智昕(Chih-Hsin Tang)*,NGF facilitates ICAM-1-dependent monocyte adhesion and M1 macrophage polarization in rheumatoid arthritis,International Immunopharmacology,2024 Mar,130():1-11 2024 . 03
4 (Kun-Tsan Lee)、(Chih-Yang Lin)、(Shan-Chi Liu)、荷琇媛(He, Xiu-Yuan)、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、(Yuan-Hsin Tsai)、(Chia-Chia Chao)、(Po-Chun Chen)*、湯智昕(Chih-Hsin Tang)*,IL-17 promotes IL-18 production via the MEK/ERK/miR-4492 axis in osteoarthritis synovial fibroblasts,Aging-US,2024 Jan,16(2):1829-1844 2024 . 01
5 柯智淵(Chih-Yuan KO)、林彥佑、(David Achudhan)、張郡崴(Chang, Jun-Way)、(Shan-Chi Liu)、(Chao-Yang Lai)、(Yuan-Li Huang)、蔡俊灝(Chun-Hao Tsai)、馮逸卿(Yi-Ching Fong)、陳賢德(Hsien-Te Chen)、(Kun-Tsan Lee)、黃建中(Huang, Chien-Chung)、(Ting-Kuo Chang)*、湯智昕(Chih-Hsin Tang)*,Omentin-1 ameliorates the progress of osteoarthritis by promoting IL-4-dependent anti-inflammatory responses and M2 macrophage polarization,International Journal of Biological Sciences,2023 Oct,19(16):5275-5289 2023 . 10
6 張喻翔(CHANG YU-HSIANG)、(Yuan-Li Huang)、蔡筱琪、(An-Chen Chang)、柯智淵(Chih-Yuan KO)、馮逸卿(Yi-Ching Fong)*、湯智昕(Chih-Hsin Tang)*,Chemokine Ligand 2 Promotes Migration in Osteosarcoma by Regulating the miR-3659/MMP-3 Axis,Biomedicines,2023 Oct,11(10):1-13 2023 . 10
7 (Yu-Ying Wu)、(Yat-Yin Law)、(Yu-Wen Huang)、Nguyen Bao T(NGUYEN BAO TRAN)、(Chih-Yang Lin)、(Chao-Yang Lai)、(Yuan-Li Huang)、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、(Ming-Chih Chou)、黃偉謙(Huang, Wei-Chien)、鄭方茹、馮逸卿(Yi-Ching Fong)*、湯智昕(Chih-Hsin Tang)*,Glutamine metabolism controls amphiregulin-facilitated chemoresistance to cisplatin in human chondrosarcoma,International Journal of Biological Sciences,2023 Oct,19(16):5174-5186 2023 . 10
8 Nguyen Bao T(NGUYEN BAO TRAN)、(Chih-Yang Lin)、(Ting-Kuo Chang)、馮逸卿(Yi-Ching Fong)、Louis Anoop(LOUIS ANOOP THADEVOOS)、(Chao-Yang Lai)、(Yuan-Li Huang)、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、(Ju-Fang Liu)、(Shun-Fa Yang)*、湯智昕(Chih-Hsin Tang)*,Melatonin inhibits chondrosarcoma cell proliferation and metastasis by enhancing miR-520f-3p production and suppressing MMP7 expression,JOURNAL OF PINEAL RESEARCH,2023 Aug,75(1): 2023 . 08
9 張瓈云(Sunny LY Chang)、(Chiang-Wen Lee)、(Chen-Yu Yang)、(Zih-Chan Lin)、(Kuo-Ti Peng)、劉軒誌(Shan-Chi Liu)、(Shih-Wei Wang)、蔡筱琪、馮逸卿(Yi-Ching Fong)、(Chao-Yang Lai)、(Yuan-Li Huang)、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、(Ju-Fang Liu)*、湯智昕(Chih-Hsin Tang)*,IOX-1 suppresses metastasis of osteosarcoma by upregulating histone H3 lysine trimethylation,BIOCHEMICAL PHARMACOLOGY,2023 Apr,210():115472 2023 . 04
10 林良蔚(Lin, Liang-Wei)、(Shih-Wei Wang)、黃偉謙(Huang, Wei-Chien)、(Thanh Kieu Huynh)、(Chao-Yang Lai)、柯智淵(Chih-Yuan KO)、馮逸卿(Yi-Ching Fong)、(Jie-Jen Lee)、(Shun-Fa Yang)*、湯智昕(Chih-Hsin Tang)*,Melatonin Inhibits VEGF-Induced Endothelial Progenitor Cell Angiogenesis in Neovascular Age-Related Macular Degeneration,Cells,2023 Mar,12(5):799 2023 . 03
11 王俞涵(Wang, Yu-Han)、蔡俊灝(Chun-Hao Tsai)、劉軒誌(Shan-Chi Liu)、陳賢德(Hsien-Te Chen)、張郡崴(Chang, Jun-Way)、柯智淵(Chih-Yuan KO)、許晉榮(Chin-Jung Hsu)、(Ting-Kuo Chang)、湯智昕(Chih-Hsin Tang)*,miR-150-5p and XIST interaction controls monocyte adherence: Implications for osteoarthritis therapy,Frontiers in Immunology,2022 Sep,13(): 2022 . 09
12 劉軒誌(Shan-Chi Liu)、(Hung-Lun Hsieh)、蔡俊灝(Chun-Hao Tsai)、馮逸卿(Yi-Ching Fong)、柯智淵(Chih-Yuan KO)、吳錫金(Hsi-Chin Wu)、張瓈云(Sunny LY Chang)、許晉榮(Chin-Jung Hsu)、湯智昕(Chih-Hsin Tang)*,CCN2 Facilitates IL-17 Production and Osteoclastogenesis in Human Osteoarthritis Synovial Fibroblasts by Inhibiting miR-655 Expression,JOURNAL OF BONE AND MINERAL RESEARCH,2022 Aug,(): 2022 . 08
13 張瓈云(Sunny LY Chang)、林彥佑、劉軒誌(Shan-Chi Liu)、(You-Shan Tsai)、(Shih-Wei Lin)、(Yen-Lien Chen)、(Chin-Chu Chen)、柯智淵(Chih-Yuan KO)、陳賢德(Hsien-Te Chen)、(Wei-Cheng Chen)*、湯智昕(Chih-Hsin Tang)*,Oral Administration of Clostridium butyricum GKB7 Ameliorates Signs of Osteoarthritis in Rats,Cells,2022 Jul,11(14):2169 2022 . 07
14 (Tsung-Ju Wu)、張?云(Sunny LY Chang)、(Chih-Yang Lin)、(Chao-Yang Lai)、(Xiu-Yuan He)、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、馮逸卿(Yi-Ching Fong)、蘇振銘(Su, Chen-Ming)*、湯智昕(Chih-Hsin Tang)*,IL-17 Facilitates VCAM-1 Production and Monocyte Adhesion in Osteoarthritis Synovial Fibroblasts by Suppressing miR-5701 Synthesis,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2022 Jun,23(12):6804 2022 . 06
15 Achudhan Dav(Achudhan David)、張?云(Sunny LY Chang)、劉軒誌(Shan-Chi Liu)、林彥佑、黃偉謙(Huang, Wei-Chien)、吳永昌(Yang-Chang Wu)、黃建中(Huang, Chien-Chung)、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、郭悅雄(Yueh-Hsiung Kuo)*、湯智昕(Chih-Hsin Tang)*,Antcin K inhibits VCAM-1-dependent monocyte adhesion in human rheumatoid arthritis synovial fibroblasts,Food & Nutrition Research,2022 Jun,66(): 2022 . 06
16 (David Achudhan)、劉軒誌(Shan-Chi Liu)、林彥佑、黃建中(Huang, Chien-Chung)、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、江宜平(I-Ping Chiang)、郭悅雄(Yueh-Hsiung Kuo)*、湯智昕(Chih-Hsin Tang)*,Antcin K Inhibits TNF-α, IL-1β and IL-8 Expression in Synovial Fibroblasts and Ameliorates Cartilage Degradation: Implications for the Treatment of Rheumatoid Arthritis,Frontiers in Immunology,2021 Dec,12():790925 2021 . 12
17 (Huey-En Tzeng)、林瑄翎(LIN SYUAN-LING)、(Louis Anoop Thadevoos)、連銘渝(Ming-Yu Lien)、楊維宏、柯智淵(Chih-Yuan KO)、林智暘、黃鈺文(Huang, Yu-Wen)、(Ju-Fang Liu)、馮逸卿(Yi-Ching Fong)、陳賢德(Hsien-Te Chen)*、湯智昕(Chih-Hsin Tang)*,Nerve growth factor promotes lysyl oxidase-dependent chondrosarcoma cell metastasis by suppressing miR-149-5p synthesis,Cell Death & Disease,2021 Nov,23(12):1101 2021 . 11
18 李翎溢(Ling-Yi Li)、林承志(Cheng-Jyh Lin)、柯智淵(Chih-Yuan KO)*,Lunate dislocation with avulsed triquetral fracture: A case report,World Journal of Clinical Cases,2021 Nov,(): 2021 . 11
19 (Yen You Lin)、柯智淵(Chih-Yuan KO)、劉軒誌(Shan-Chi Liu)、王俞涵(Wang, Yu-Han)、許晉榮(Chin-Jung Hsu)、蔡俊灝(Chun-Hao Tsai)、(Tsung Ju Wu)*、湯智昕(Chih-Hsin Tang)*,miR-144-3p ameliorates the progression of osteoarthritis by targeting IL-1β: Potential therapeutic implications,JOURNAL OF CELLULAR PHYSIOLOGY,2021 Oct,236(10):6988-7000 2021 . 10
20 (Kun-Tsan Lee)、(Bo-Cheng Chen)、劉軒誌(Shan-Chi Liu)、林彥佑、蔡俊灝(Chun-Hao Tsai)、柯智淵(Chih-Yuan KO)、湯智昕(Chih-Hsin Tang)*、(Kwong-Chung Tung)*,Nesfatin-1 facilitates IL-1β production in osteoarthritis synovial fibroblasts by suppressing miR-204-5p synthesis through the AP-1 and NF-κB pathways,Aging-US,2021 Sep,13(): 2021 . 09
21 (Huey-En Tzeng)、林瑄翎(LIN SYUAN-LING)、(Louis-Anoop Thadevoos)、柯智淵(Chih-Yuan KO)、(Ju-Fang Liu)、(Yu-Wen Huang)、(Chih-Yang Lin)、馮逸卿(Yi-Ching Fong)*、湯智昕(Chih-Hsin Tang)*,The mir-423-5p/MMP-2 Axis Regulates the Nerve Growth Factor-Induced Promotion of Chondrosarcoma Metastasis,Cancers,2021 Jul,13(13):3347 2021 . 07
22 陳冠儒(CHEN,KUAN-JU)、柯智淵(Chih-Yuan KO)、何宗祐(Tsung-Yu Ho)、陳賢德(Hsien-Te Chen)、許弘昌(Horng-Chaung Hsu)、洪誌鴻(Chi-Horng Horng)*,A combination of bimalleolar fracture and fracture on talar body and neck: A rare case report,MEDICINE,2020 May,(): 2020 . 05

研討會論文

研討會論文/Conference Papers
(發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目)
日期
1 多個空心螺絲和股骨頸系統(FNS)治療不同Pauwels types股骨頸骨折的研究比較Comparison of multiple cannulated screws and femoral neck system (FNS) in low or high grade Pauwels types femoral neck fracture: A cohort study,中華民國骨科醫學會【113年度第86次聯合學術研討會】,台北萬豪酒店,2024.10.26~2024.10.27, 2024 . 10
2 Metal-reinforced antibiotics cement articulating spacer for Prosthetic Knee Infection-a preliminary study,中華民國骨科醫學會113年度第86次聯合學術研討會,Taipei Marriott Hotel,2024.10.26~2024.10.27, 2024 . 10
3 Preventing Mechanical Complications of Knee Spacer Implantation: A Radiographic Analysis of 203 CADAS Articulating Spacers,中華民國骨科醫學會113年度第85次春季聯合學術研討會,彰化基督教醫院-國際培訓中心,2024.04.20~2024.04.20, 2024 . 04
4 Preliminary Exploration of Implementing Enhanced Recovery After Surgery (ERAS) Protocols in Total Knee and Hip Arthroplasy: A Single-center Retrospective Analysis,2024台灣疼痛醫學會年會暨國際學術研討會,張榮發基金會國際會議中心,2024.04.27~2024.04.28, 2024 . 04
5 The Preliminary Function Result of Mesenchymal Stem Cell Therapy in the Treatment of Knee Osteoarthritis: CMUH Experience 中國附醫使用自體骨髓幹細胞治療膝關節炎 的初步結果及經驗,中華民國骨科醫學會【111年第81次春季聯合學術研討會】,高雄萬豪酒店,2022.04.9 ~2022.04.9 , 2022 . 04
6 Trend of annular incidence and treatment of pelvic/acetabular fracture in the elderly ,the feature we face in an ageing society,中華民國骨科學會110 年度第80 次聯合學術研討會,台北萬豪酒店,2021.12.30~2021.12.31, 2021 . 12
7 Treatment Strategies in PIPJ Injuries,中華民國骨科醫學會105年度第71次聯合學術研討會,張榮發基金會國際會議中心,2016.10.22~2016.10.23, 2016 . 10
8 Application of Vascularized Bone Graft in Trauma Patients,中華民國骨科醫學會105年度第71次聯合學術研討會,張榮發基金會國際會議中心,2016.10.22~2016.10.23, 2016 . 10
9 Percutaneous Anterior Column Screw Fixation For Displaced Anterior Acetabulum And Pubic Bone Fractures,中華民國骨科醫學會105年度第71次聯合學術研討會,張榮發基金會國際會議中心,2016.10.22~2016.10.23, 2016 . 10
10 Wrist gouty arthritis presenting as scaphoid erosion with scapholunate ligament disruption,中華民國骨科醫學會104年度第68次春季聯合學術研討會,嘉義長庚醫院,2015.04.25~2015.04.25, 2015 . 04
11 Severe femoral deformity treated with extensive porous-coated stem in revision hip arthroplasty,中華民國骨科醫學會102年度第65次聯合學術研討會,國防醫學院,2013.10.26~2013.10.27, 2013 . 10
12 Posterolateral Approach without Fibular Osteotomy for High Energy Posterior Tibial Plateau Fractures,中華民國骨科醫學會101年度第63次聯合學術研討會,台北世貿,2012.10.27~2012.10.28, 2012 . 10
13 A new concept of surgical approach for posterior tibial plateau fractures-case series,中華民國骨科醫學會101年度第62次春季聯合學術研討會,新竹喜來登,2012.04.21~2012.04.21, 2012 . 04
14 an unusual recurrent elbow dislocation,中華民國骨科醫學會 100年度第61次聯合學術研討會,台北榮民總醫院,2011.10.29~2011.10.30, 2011 . 10
15 Treatment of Alendronate Related Atypical Femoral Shaft Fractures wth Strontium Ranelate : A Case Report,中華民國骨科醫學會100 年度第61 次聯合學術研討會,台北,2011.10.29~2011.10.30, 2011 . 10
16 Boerhaave’s syndrome after postoperative nausea and vomiting: A case report,中華民國骨科醫學會100年度第60次春季聯合學術研討會,高雄長庚,2011.04.23~2011.04.23, 2011 . 04
17 Case report : a 25-year-old female with artificial ACL ligament early failure,The Combined Conference of 15th Triennial Congress of Asia Pacific Orthopaedic Association and 59th,台北,2010.11.04~2010.11.07, 2010 . 11
18 A case report: Long term used Alendronate related atraumatic femoral shaft fracture,中華民國骨科醫學會99年度第58次春季聯合學術研討會 ,台中,2010.04.24~2010.04.24, 2010 . 04

專書

暫無資料

研究計畫

研究計畫/Research Grant
(研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,計畫期間)
日期
1 個別型,CMU113-ASIA-05,柯智淵(Chih-Yuan KO)、賴朝陽,本校(含附醫),骨腫瘤機轉研究平台,2024.8.1~2025.7.31 2024 . 08
2 個別型,CMU112-ASIA-10,柯智淵(Chih-Yuan KO)、黃元勵,本校(含附醫),骨腫瘤機轉研究平台,2023.8.1~2024.7.31 2023 . 08
3 整合型(召集人、總主持人),CMU111-ASIA-05,柯智淵(Chih-Yuan KO)、賴朝陽,本校(含附醫),骨腫瘤機轉研究平台,2022.8.1~2023.7.31 2022 . 08
4 個別型,CMU110-ASIA-08,柯智淵(Chih-Yuan KO)、賴朝陽,本校(含附醫),骨腫瘤機轉研究平台,2021.8.1~2022.7.31 2021 . 08

專利技術

暫無資料

獲獎事蹟

暫無資料

技術轉移

暫無資料
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