醫師學術論文
Paper陳柏谷 Po-Ku Chen 博士後研究員
陳柏谷博士專長於細胞生物學、癌症生物學與自體發炎性疾病機制的探討。目前研究方向分為自體發炎性疾病致病機制與分子機轉的研究;另外,積極的參與間葉幹細胞於治療自體免疫疾病研究。
相關連結
學術機構典藏
論文
期刊論文
期刊論文/Journal Paper (作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄) |
日期 | |
1 | 張敬昆(Ching-Kun Chang)、李宜珍(Yi-Chen Li)、陳柏谷(Po-Ku Chen)、張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)*,Elevated remnant cholesterol as a potential predictor for cardiovascular events in rheumatoid arthritis patients,Frontiers in Cardiovascular Medicine,2024 Sep,11():1449219 | 2024 . 09 |
2 | 陳柏谷(Po-Ku Chen)、張詩欣(Shih-Hsin Chang)、陳一銘(Yi-Ming Chen)、陳信華(Hsin-Hua Chen)、黃柏豪(Po-Hao Huang)、黃建中(Huang, Chien-Chung)、楊凱介(YEO KAI-JIEH)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Prior herpes zoster occurrence and high-dose corticosteroids increase herpes zoster risk in rheumatoid arthritis patients receiving janus kinase inhibitors in a retrospective and observational study,CLINICAL RHEUMATOLOGY,2024 Aug,43(8):2503-2511 | 2024 . 08 |
3 | 陳一銘(Yi-Ming Chen)、陳柏谷(Po-Ku Chen)、張詩欣(Shih-Hsin Chang)、陳信華(Hsin-Hua Chen)、(Jun-Peng Chen)、譚國棟(Kuo-Tung Tang)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Baseline ANA and Anti-Ro60/SSA Antibody as Potential Predictors for Immunogenicity and Poor EULAR Response in Adalimumab-Treated RA Patients,JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS,2024 Aug,2024():9 | 2024 . 08 |
4 | 陳柏谷(PoKu Chen)、陳一銘(Yi-Ming Chen)、陳信華(Hsin-Hua Chen)、廖采苓(Tsai-Ling Liao)、張詩欣(Shih-Hsin Chang)、楊凱介(YEO KAI-JIEH)、黃柏豪(Po-Hao Huang)、陳得源(Der-Yuan Chen)*,Association of the Reduced Levels of Monocyte Chemoattractant Protein-1 with Herpes Zoster in Rheumatoid Arthritis Patients Treated with Janus Kinase Inhibitors in a Single-Center Cohort,Microorganisms,2024 May,12(5):974 | 2024 . 05 |
5 | 陳柏谷(PoKu Chen)、許偉帆(Hsu, Wei-Fan)、彭成元(Peng, Cheng-Yuan)、廖采苓(Tsai-Ling Liao)、張詩欣(Shih-Hsin Chang)、陳信華(Hsin-Hua Chen)、陳珠璜(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,Significant association of elevated serum galectin-9 levels with the development of non-alcoholic fatty liver disease in patients with rheumatoid arthritis,Frontiers in Medicine,2024 Feb,11():1347268 | 2024 . 02 |
6 | 陳柏谷(PoKu Chen)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)*,The NLRP3 Inflammasome as a Pathogenic Player Showing Therapeutic Potential in Rheumatoid Arthritis and Its Comorbidities: A Narrative Review,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2024 Jan,25(1):626 | 2024 . 01 |
7 | 何瑋立(Wei-Li Ho)、陳信華(Hsin-Hua Chen)、陳柏谷(PoKu Chen)、廖采苓(Tsai-Ling Liao)、張詩欣(Shih-Hsin Chang)、陳一銘(Yi-Ming Chen)、林敬恒(Ching-Heng Lin)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)*,Increased NAFLD risk in newly diagnosed patients with RA during the first 4 years of follow-up: a nationwide, population-based cohort study,BMJ Open,2024 Jan,14(1):e079296 | 2024 . 01 |
8 | 林昀嫻(Yun-Hsien Lin)、張詩欣(Shih-Hsin Chang)、許登傑(Teng-Chieh Hsu)、陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Elevated monocyte distribution width in patients with active adult-onset Still’s disease: a novel activity indicator,CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,2023 Jul,(): | 2023 . 07 |
9 | 張敬昆、蔣恩沛(En-Pei Isabel Chiang)、張光喜(Kuang-Hsi Chang)、譚國棟(Kuo-Tung Tang)、陳柏谷(PoKu Chen)、葉晞彤(YIP HEI-TUNG)、(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,The Sizes and Composition of HDL-Cholesterol Are Significantly Associated with Inflammation in Rheumatoid Arthritis Patients,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2023 Jun,24(13):10645 | 2023 . 06 |
10 | 張敬昆、張光喜(Kuang-Hsi Chang)、鄭維中(Cheng, Wei-Chung)、陳柏谷(PoKu Chen)、蔣恩沛(En-Pei Isabel Chiang)、張詩欣(Shih-Hsin Chang)、(Yi-Chen Li)、陳珠璜(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,Lipid metabolomic signature might predict subclinical atherosclerosis in patients with active rheumatoid arthritis,CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,2023 May,41(5):1120-1128 | 2023 . 05 |
11 | 陳柏谷(PoKu Chen)、楊凱介(Yeo Kai Jieh)、張詩欣(Shih-Hsin Chang)、廖采苓(Tsai-Ling Liao)、周家卉(Chia-Hui Chou)、藍忠亮(Joung-Liang Lan)、張敬昆、陳得源(Der-Yuan Chen)*,The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity,Virology Journal,2023 Feb,20(33): | 2023 . 02 |
12 | 陳柏谷(PoKu Chen)、廖采苓(Tsai-Ling Liao)、張詩欣(Shih-Hsin Chang)、楊凱介(Yeo Kai Jieh)、周家卉(Chia-Hui Chou)、陳得源(Der-Yuan Chen)*,High-titer anti-interferon-g neutralizing autoantibodies linked to opportunistic infections in patients with adult-onset still’s disease,Frontiers in Medicine,2023 Jan,9():1097514 | 2023 . 01 |
13 | 張詩欣(Shih-Hsin Chang)、許登傑(Teng-Chieh Hsu)、黃柏豪(Po-Hao Huang)、黃建中(Huang, Chien-Chung)、楊凱介(Yeo Kai Jieh)、洪偉哲(Wei-Jhe Hong)、陳柏谷(PoKu Chen)、林昀嫻(Yun-Hsien Lin)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,A Streamlined Diagnostic Process Improved the Outcomes of Patients with Adult-Onset Still’s Disease: A Single-Center Retrospective Observational Study,Rheumatology and Therapy,2022 Dec,(2022): | 2022 . 12 |
14 | 陳柏谷(PoKu Chen)、魏秀娟(Shiow-Jiuan Wey)、陳得源(Der-Yuan Chen)*,Interleukin-18: a biomarker with therapeutic potential in adult-onset Still's disease,Expert Review of Clinical Immunology,2022 Jul,():1-11 | 2022 . 07 |
15 | (Yi-Ming Chen)、(I-Chieh Chen)、(Ya-Hsuan Chao)、(Hsin-Hua Chen)、陳柏谷(PoKu Chen)、張詩欣(Shih-Hsin Chang)、楊凱介(Yeo Kai Jieh)、(Shiow-Jiuan Wey)、林季千(Chi-Chien Lin)*、陳得源(Der-Yuan Chen)*,Dextromethorphan Exhibits Anti-Inflammatory and Immunomodulatory Effects in a Murine Model: Therapeutic Implication in Psoriasis,Life-Basel,2022 May,12(5):696 | 2022 . 05 |
16 | 田霓(Ni Tien)、張煜昌(Yu-Chang Chang)、陳柏谷(PoKu Chen)、林惠茹(Hui-Ju Lin)、張詩欣(Shih-Hsin Chang)、藍忠亮(Joung-Liang Lan)、薛博仁(Hsueh, Po-Ren)、張敬昆、陳得源(Der-Yuan Chen)*,The Immunogenicity and Safety of Three Types of SARS-CoV-2 Vaccines in Adult Patients with Immune-Mediated Inflammatory Diseases: A Longitudinal Cohort Study,Biomedicines,2022 Apr,10(4):911 | 2022 . 04 |
17 | 張敬昆、鄭維中(Cheng, Wei-Chung)、馬文隆(Wen-Lung Ma)、陳柏谷(PoKu Chen)、(Chu-Huang Chen)、沈培鈞(Pei-Chun Shen)、(Chia-Ching Chen)、張詩欣(Shih-Hsin Chang)、賴怡樺(LAI YI-HUA)、陳得源(Der-Yuan Chen)*,The Potential Role of Electronegative High-Density Lipoprotein H5 Subfraction in RA-Related Atherosclerosis,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2021 Oct,22(21):11419 | 2021 . 10 |
18 | 陳柏谷(PoKu Chen)、楊凱介(Yeo Kai Jieh)、黃柏豪(Po-Hao Huang)、張詩欣(Shih-Hsin Chang)、張敬昆、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Increased Lipid Peroxidation May Be Linked to Ferritin Levels Elevation in Adult-Onset Still’s Disease,Biomedicines,2021 Oct,9(11):1508 | 2021 . 10 |
19 | 楊晶安(Yang, Chin-An)、陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、張敬昆、張建國(Jan-Gowth Chang)、張詩欣(Shih-Hsin Chang)、林季千(Chi-Chien Lin)、陳得源(Der-Yuan Chen)*,Expression signature of inflammation-associated long non-coding RNAs in adult-onset Still’s disease,CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,2021 Sep,39Suppl132(5):67-74 | 2021 . 09 |
20 | 張敬昆、陳柏谷(PoKu Chen)、(Chia-Ching Chen)、張詩欣(Shih-Hsin Chang)、(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,Increased Levels of Omega-3 Fatty Acids and DHA Are Linked to Pain Reduction in Rheumatoid Arthritis Patients Treated with Janus Kinase Inhibitors,Nutrients,2021 Aug,13(9):3050 | 2021 . 08 |
21 | 廖采苓(Tsai-Ling Liao)、陳一銘(Yi-Ming Chen)、譚國棟(Kuo-Tung Tang)、陳柏谷(PoKu Chen)、劉宏仁(Hung-Jen Liu)、陳得源(Der-Yuan Chen)*,MicroRNA-223 inhibits neutrophil extracellular traps formation through regulating calcium influx and small extracellular vesicles transmission,Scientific Reports,2021 Aug,11(1): | 2021 . 08 |
22 | 陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、黃柏豪(Po-Hao Huang)、徐婕琳(Hsu, Jye-Lin)、張敬昆、田霓(Ni Tien)、林惠茹(Hui-Ju Lin)、陳得源(Der-Yuan Chen)*,Interleukin-18 Is a Potential Biomarker to Discriminate Active Adult-Onset Still’s Disease From COVID-19,Frontiers in Immunology,2021 Jul,12(): | 2021 . 07 |
23 | 陳柏谷(PoKu Chen)、陳得源(Der-Yuan Chen)*,An Update on the Pathogenic Role of Macrophages in Adult-Onset Still’s Disease and Its Implication in Clinical Manifestations and Novel Therapeutics,Journal of Immunology Research,2021 Jun,2021(): | 2021 . 06 |
24 | 陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、陳一銘(Yi-Ming Chen)、陳信華(Hsin-Hua Chen)、張詩欣(Shih-Hsin Chang)、鍾加明(Chia-Min Chung)、(Nurul H. Rutt)、(Ti-Myen Tan)、(Raja Nurashirin Raja Mamat)、(Nur Diana Anuar)、(Jonathan M. Blackburn)、陳得源(Der-Yuan Chen)*,Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA,Journal of Immunology Research,2021 Mar,2021(): | 2021 . 03 |
25 | 陳一銘(Yi-Ming Chen)、陳柏谷(PoKu Chen)、張敬昆、林季千(Chi-Chien Lin)、陳信華(Hsin-Hua Chen)、藍忠亮(Joung-Liang Lan)、張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)*,Association of Apolipoprotein E Polymorphism with Adipokines and Cardiovascular Disease Risk in Rheumatoid Arthritis Patients,Life-Basel,2020 Dec,10(12):330 | 2020 . 12 |
26 | 張敬昆、陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、張詩欣(Shih-Hsin Chang)、謝祖怡(Tsu-Yi Hsieh)、廖佩娟(LIAO PEI-JYUAN)、陳珠璜(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,Association of Electronegative LDL with Macrophage Foam Cell Formation and CD11c Expression in Rheumatoid Arthritis Patients,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2020 Aug,21(16):E5883 | 2020 . 08 |
27 | 陳柏谷(PoKu Chen)、謝世良(Shie-Liang Hsieh)、藍忠亮(Joung-Liang Lan)、林季千(Chi-Chien Lin)、張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)*,Elevated Expression of C-Type Lectin Domain Family 5-Member A (CLEC5A) and Its Relation to Inflammatory Parameters and Disease Course in Adult-Onset Still's Disease.,Journal of Immunology Research,2020 Apr,2020():1-11 | 2020 . 04 |
28 | 陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、李如璧(Ju-Pi Li)、張敬昆、張詩欣(Shih-Hsin Chang)、黃柏豪(Po-Hao Huang)、楊凱介(Yeo Kai Jieh)、陳得源(Der-Yuan Chen)*,Elevated plasma galectin-3 levels and their correlation with disease activity in adult-onset Still’s disease,CLINICAL RHEUMATOLOGY,2020 Jan,():1-8 | 2020 . 01 |
29 | 陳柏谷(PoKu Chen)、花俊宏(Chun-Hung Hua)、(Hui-Ting Hsu)、(Tzer-Min Kuo)、鍾加明(Chia-Min Chung)、(Chi-Pin Lee)、蔡銘修(Ming-Hsui Tsai)、(Kun-Tu Yeh)、葛應欽(Ying-Chin Ko)*,ALPK1 expression is associated with lymph node metastasis and tumor growth in oral squamous cell carcinoma patients,AMERICAN JOURNAL OF PATHOLOGY,2018 Sep,(): | 2018 . 09 |
研討會論文
研討會論文/Conference Papers (發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目) |
日期 | |
1 | 微小RNA-223藉由調節鈣流入與外泌體傳遞來抑制成人型史笛兒氏症患者之嗜中性球細胞外網,2021年中華民國風濕病醫學會年會,線上會議,2021.10.29~2021.10.31, | 2021 . 10 |
2 | 結合血液檢測之長鏈非編碼核糖核酸與細胞激素的分類模式可用來診斷成人型史笛兒氏症及預測其疾病病程,2020社團法人中華民國風濕病學會會員大會暨學術研討會,台北新板希爾頓酒店,2020.10.30~2020.11.1 , | 2020 . 10 |
專書
暫無資料研究計畫
研究計畫/Research Grant (研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,計畫期間) |
日期 | |
1 | 個別型,DMR-113-119,陳得源(Der-Yuan Chen),本校(含附醫),骨髓來源的抑制細胞與風濕疾病患者疾病活動度指標及其感染之關聯性,2023.8.1~2024.7.31 | 2023 . 08 |
2 | 個別型,DMR-113-011,陳柏谷(PoKu Chen),附醫院內計畫,異體脂肪組織幹細胞治療對於結締組織疾病併發間質性肺病變患者免疫反應的影響,2023.8.1~2024.7.31 | 2023 . 08 |
3 | 整合型(召集人、總主持人),NSTC 112-2218-E-039-001,陳健尉、黃文男、張啟聖、許凱程(HSU KAI-CHENG)、黃建中(Huang, Chien-Chung)、陳柏谷(PoKu Chen)、陳一銘,科技部,利用全基因體定序、胜肽體、外泌體及微型核醣核酸剖繪之人工智慧分析,創新開發「智抗炎」晶片,選出類風濕性關節炎患者最適藥物之精準醫療(2/3),2023.8.1~2024.7.31 | 2023 . 08 |
4 | 整合型(召集人、總主持人),NSTC 111-2218-E-039-001,陳健尉、黃文男、張啟聖、許凱程(HSU KAI-CHENG)、黃建中(Huang, Chien-Chung)、陳柏谷(PoKu Chen)、陳一銘,科技部,利用全基因體定序、胜肽體、外泌體及微型核醣核酸剖繪之人工智慧分析,創新開發「智抗炎」晶片,選出類風濕性關節炎患者最適藥物之精準醫療(1/3),2022.8.1~2023.7.31 | 2022 . 08 |
5 | 個別型,MOST 111-2314-B-039-010,陳得源(Der-Yuan Chen)、彭成元(Peng, Cheng-Yuan),科技部,利用生物醫學模式探求風濕病患者發生非酒精性脂肪肝病變之新穎生物標誌與治療標靶,2022.8.1~2023.7.31 | 2022 . 08 |
6 | 個別型,DMR-110-021,黃柏豪(Po-Hao Huang)、陳柏谷(PoKu Chen),附醫院內計畫,風濕疾病患者高鐵蛋白血症之致病機制及新冠狀病毒感染之關聯性,2020.8.1~2021.7.31 | 2020 . 08 |
7 | 個別型,DMR-108-165,陳得源(Der-Yuan Chen),附醫院內計畫,半乳糖凝集素與C-型凝集素在自體發炎疾病之致病角色及與發炎小體關聯性,2018.8.1~2019.6.30 | 2018 . 08 |
專利技術
暫無資料獲獎事蹟
獲獎/Award (獲獎名稱,給獎單位,獲獎日期) |
日期 | |
1 | 中華民國風濕病學會第38屆學術研討會-陳正言教授最佳年會論文獎,社團法人中華民國風濕病學會,2021.10.31 | 2021 . 10 |
2 | 社團法人中華民國風濕病醫學會2021學術研討會優秀論文獎,社團法人中華民國風濕病醫學會,2021.10.31 | 2021 . 10 |