鍾正明 Cheng-Ming Chuong 資深科學顧問
鍾正明教授為我中央研究院院士，美國科學促進會院士，美國南加州大學病理系教授、中國醫藥大學整合幹細胞中心資深科學顧問。鍾院士引領世界外胚層器官如皮膚及其附屬器官羽毛、毛囊的發育、再生及幹細胞組織工程等研究，為細胞粘結、組織器官形態發生、組態形成等研究做出了開拓性的貢獻。在包括國際頂尖雜誌Nature, Science和Cell等共發表論文200餘篇，他引次數超過萬次。其研究成果獲選Science雜誌2014年度十大科學突破。
相關連結
學術機構典藏
論文
期刊論文
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期刊論文／Journal Paper (作者群，論文題目，期刊名稱，出版年月，卷號(期別):頁次起迄) |
日期 | |
| 1 | (Erin Lynn Weber)、賴勇志(Yung-Chih Lai)、雷明星(Mingxing Lei)、(Ting-Xin Jiang)、鍾正明(Cheng-Ming Chuong)*，Human fetal scalp dermal papilla enriched genes and the role of R-spondin-1 in the restoration of hair neogenesis in adult mouse cells，Frontiers in Cell and Developmental Biology，2020 Nov，8(583434):1-11 | 2020 . 11 |
| 2 | 嚴玉婷、簡崇美(May Chien)、賴勇志(Yung-Chih Lai)、(DP-Chen)、鍾正明(Cheng-Ming Chuong)、洪明奇、洪士杰(Shih-Chieh Hung)*，PP2A deficiency enhances carcinogenesis of Lgr5+ intestinal stem cells both in organoids and in vivo.，Cells，2020 Jan，9(1):90 | 2020 . 01 |
| 3 | (Xiao-shan Wu)、(Chao-yuan Yeh)、(Hans I-Chen Harn)、(Ting-Xing Jiang)、(Ping Wu)、(Randall B. Widelitz)、(Ruth E. Baker)、鍾正明(Cheng-Ming Chuong)*，Self-assembly of biological networks via adaptive patterning revealed by avian intradermal muscle network formation，PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA，2019 May，116(22): | 2019 . 05 |
| 4 | (Masafumi Inaba)、(Ting-Xin Jiang)、梁雅珍(Ya-Chen Liang)、蔡迪姍(Stephanie Tsai)、賴勇志(Yung-Chih Lai)、(Randall Bruce Widelitz)、鍾正明(Cheng-Ming Chuong)*，Instructive role of melanocytes during pigment pattern formation of the avian skin，PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA，2019 Apr，116(14):6884-6890 | 2019 . 04 |
| 5 | (Tin-Xin Jiang)、(Hans I-Chen Harn)、(Kuang-Ling Ou)、雷明星(Ming-Xing Lei)、鍾正明(Cheng-Ming Chuong)*，Comparative regenerative biology of spiny (Acomys cahirinus) and laboratory (Mus musculus) mouse skin，EXPERIMENTAL DERMATOLOGY，2019 Apr，28(4):442-449 | 2019 . 04 |
| 6 | (Weiming Qiu)、鍾正明(Cheng-Ming Chuong)、雷明星(Ming-Xing Lei)*，Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials，EXPERIMENTAL DERMATOLOGY，2019 Apr，28(4):395-405 | 2019 . 04 |
| 7 | 李雲先(LEE YUN-SHAIN)、梁雅珍(Ya-Chen Liang)、(Ping Wu)、(David A. Kulber)、(Kylie Tanabe)、鍾正明(Cheng-Ming Chuong)、(Randall Widelitz)、(Tai?Lan Tuan)*，STAT3 Signaling Pathway is Implicated in Keloid Pathogenesis by Preliminary Transcriptome and Open Chromatin Analyses，EXPERIMENTAL DERMATOLOGY，2019 Mar，(): | 2019 . 03 |
| 8 | (Wen-Ching Shen)、賴勇志(Yung-Chih Lai)、(Ling-Hui Li)、(Kolin Liao)、(Hung-Chang Lai)、(Shou-Yen Kao)、王約翰(John Wang)、鍾正明(Cheng-Ming Chuong)、洪士杰(Shih-Chieh Hung)*，Methylation and PTEN activation in dental pulp mesenchymal stem cells promotes osteogenesis and reduces oncogenesis，Nature Communications，2019 Mar，10(): | 2019 . 03 |
| 9 | (Erin L. Weber)、(Thomas E. Woolley)、(Chao?Yuan Yeh)、(Kuang?Ling Ou)、(Philip K. Maini)、鍾正明(Cheng-Ming Chuong)*，Self‐organizing hair peg‐like structures from dissociated skin progenitor cells: New insights for human hair follicle organoid engineering and Turing patterning in an asymmetric morphogenetic field，EXPERIMENTAL DERMATOLOGY，2019 Jan，28(4):355-366 | 2019 . 01 |
| 10 | (Randall B. Widelitz)、林季瑋(Gee-Way Lin)、賴勇志(Yung-Chih Lai)、(Julie A. Mayer)、(Pin-Chi Tang)、(Hsu-Chen Cheng)、(Ting-Xin Jiang)、(Chih-Feng Chen)、鍾正明(Cheng-Ming Chuong)*，Morpho-regulation in diverse chicken feather formation: Integrating branching modules and sex hormone-dependent morpho-regulatory modules，DEVELOPMENT GROWTH & DIFFERENTIATION，2019 Jan，61(1):124-138 | 2019 . 01 |
| 11 | Ang Li、(Jung-Hwa Cho)、(Brian Reid)、(Chun-Chih Tseng)、(Lian He)、(Peng Tan)、葉肇元(Chao-Yuan Yeh)、(Ping Wu)、(Yuwei Li)、(Randall B. Widelitz)、(Yubin Zhou)、(Min Zhao)、(Robert H. Chow)、鍾正明(Cheng-Ming Chuong)*，Calcium oscillations coordinate feather mesenchymal cell movement by SHH dependent modulation of gap junction networks，Nature Communications，2018 Dec，9():5377 | 2018 . 12 |
| 12 | (Ping Wu)、賴勇志(Yung-Chih Lai)、(Randall Widelitz)、鍾正明(Cheng-Ming Chuong)*，Comprehensive molecular and cellular studies suggest avian scutate scales are secondarily derived from feathers, and more distant from reptilian scales，Scientific Reports，2018 Nov，8():13 | 2018 . 11 |
| 13 | 雷明星(Ming-Xing Lei)、鍾正明(Cheng-Ming Chuong)*，【Editorial Material】Epidermal Darwinism and Competitive Equilibrium within the Epidermis，Cell Stem Cell，2018 Nov，23(5):627-629 | 2018 . 11 |
| 14 | 賴勇志(Yung-Chih Lai)、梁雅珍(Ya-Chen Liang)、(Ting-Xin Jiang)、(Randall B. Widelitz)、(Ping Wu)、鍾正明(Cheng-Ming Chuong)*，Transcriptome analyses of reprogrammed feather / scale chimeric explants revealed co-expressed epithelial gene networks during organ specification，BMC GENOMICS，2018 Oct，19(1):780 | 2018 . 10 |
| 15 | (Michael W.Hughes)、(Ting-XinJiang)、(Maksim V.Plikus)、(FernandoGuerrero-Juare)、(Chien-HongLin)、(ChristopherSchafer)、(RobertMaxson)、(Randall B.Widelitz)、鍾正明(Cheng-Ming Chuong)*，Msx2 supports epidermal competency during wound induced hair follicle neogenesis，JOURNAL OF INVESTIGATIVE DERMATOLOGY，2018 May，31736(6): | 2018 . 05 |
| 16 | 吳平(Ping Wu)、嚴洁(Jie Yan)、賴勇志(Lai, Yung-Chih)、(Chen Siang Ng)、(Ang Li)、(Xueyuang JIang)、(Ruth M. Elsey)、(Randall Widelitz)、(Ruchi Bajpai)、李文雄(Wen-Hsiung Li)、鍾正明(Cheng-Ming Chuong)*，Multiple regulatory modules are required for scale-to-feather conversion，MOLECULAR BIOLOGY AND EVOLUTION，2018 Feb，35(2):417-430 | 2018 . 02 |
| 17 | (Cooke TF)、(Fischer CR)、(Wu P)、(Jiang TX)、(Xie KT)、(Kuo J)、(Doctorov E)、(Zehnder A)、(Khosla C)、鍾正明(Cheng-Ming Chuong)、(Bustamante CD)*，Genetic Mapping and Biochemical Basis of Yellow Feather Pigmentation in Budgerigars，CELL，2017 Oct，171(2):427-439 | 2017 . 10 |
| 18 | (Jung-Hwa Cho)、(Carter J. Swanson)、(Jeannie Chen)、(Ang Li)、(Lisa G. Lippert)、(Shannon E. Boye)、(Kasey Rose)、(Sivaraj Sivaramakrishnan)、鍾正明(Cheng-Ming Chuong)、(Robert H. Chow)*，The GCaMP‐R Family of Genetically Encoded Ratiometric Calcium Indicators，ACS Chemical Biology，2017 Apr，12(4):1066-1074 | 2017 . 04 |
| 19 | 李昂(Ang Li)、(Seth Figueroa)、(Ting-Xin Jiang)、(Ping Wu)、(Randall Widelitz)、(Qing Nie)、鍾正明(Cheng-Ming Chuong)*，Diverse feather shape evolution enabled by coupling anisotropic signallig modules with self-organizing branching programme，Nature Communications，2017 Jan，8():14139 | 2017 . 01 |
| 20 | (S. Tsai)、(A. Abdelhamid)、(M.K. Khan)、(A. Elkarargy)、(R.B. Widelitz)、鍾正明(Cheng-Ming Chuong)、(P. Wu)*，The Molecular Circuit Regulating Tooth Development in Crocodilians，JOURNAL OF DENTAL RESEARCH，2016 Dec，95(13):1501-1510 | 2016 . 12 |
| 21 | (Randall Widelitz)*、鍾正明(Cheng-Ming Chuong)*，Quorum sensing and other collective regenerative behavior in organ populations，CURRENT OPINION IN GENETICS & DEVELOPMENT，2016 Oct，40():183-143 | 2016 . 10 |
| 22 | 陳志強(Chih-Chiang Chen)、(Maksim V. Plikus)、唐品琦(Pin-Chi Tang)、(Randall B. Widelitz)、鍾正明(Cheng-Ming Chuong)*，The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration，JOURNAL OF MOLECULAR BIOLOGY，2016 Apr，428():1423-1440 | 2016 . 04 |
| 23 | 黃禎祥(Chen Siang Ng)、陳志冠(Chih-Kuan Chen)、(Wen-Lang Fan)、(Ping Wu)、(Siao-Man Wu)、(Jiun-Jie Chen)、(Yu-Ting Lai)、(Chi-Tang Mao)、(Mei-Yeh Jade Lu)、(Di-Rong Chen)、(Ze-Shiang Lin)、(Kai-Jung Yang)、(Yuan-An Sha)、(Tsung-Che Tu)、(Chih-Feng Chen)、鍾正明(Cheng-Ming Chuong)、李文雄*，Transcriptomic analyses of regenerating adult feathers in chicken，BMC GENOMICS，2015 Oct，16(): | 2015 . 10 |
研討會論文
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研討會論文／Conference Papers (發表主題或論文名稱，研討會名稱，演講地點，研討會期間，受邀演講題目) |
日期 | |
| 1 | The Making of a Flight Feather:Temporal-spatial WNT/β-catenin gradient within the dermal papilla regulates region-specific barb branch organization，2020 Taiwan Society of Developmental biology International Conference，國立中興大學，2020.08.07~2020.08.08， | 2020 . 08 |
| 2 | Temporo-spatial chromatin organization of multiplex keratin clusters orchestrates skin regional specification，Chromatin Architecture and Chromosome Organization，Whistler, Canada，2018.03.23~2018.03.27， | 2018 . 03 |
| 3 | Epigenetic Basis of Region-Specific Skin Formation，The 20th Annual Pathology Conference of USC，Crown Plaza Redondo Beach & Marina, Redondo Beach, California, USA，2017.03.03~2017.03.04， | 2017 . 03 |
專書
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專書／Books (作者，書名，出版商，出版日期) |
日期 | |
| 1 | 梁雅珍(Ya-Chen Liang)、(Randall B. Widelitz)、鍾正明(Cheng-Ming Chuong)，表觀遺傳學與皮膚發育及再生，Humana Press, Cham，2018.9 | 2018 . 09 |
| 2 | 蔡迪姍(Stephanie Tsai)、(Randal B. Widelitz)、(Alaa Abdelhamid)、鍾正明(Cheng-Ming Chuong)*，局部訊號決定器官成型，，2017.9 | 2017 . 09 |
