醫師學術論文
Paper蔡嘉哲 Gregory J Tsay 顧問主治醫師
蔡嘉哲醫師專長診斷各種不同表現之關節炎,關節炎包括類風濕性關節、僵直性脊椎炎、乾癬症、血管炎、痛風、退化性關節炎、硬皮症等等,這些疾病需早期診斷及治療,延誤治療將導致疾病之關節變形甚至殘障。
學術機構典藏
論文
期刊論文
期刊論文/Journal Paper (作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄) |
日期 | |
1 | 唐健綸(Chien-Lun Tang)、(Chen-Feng Chiu)、(Shan-hui Hsu)、(Song-Yi Yan)、(Chun-Yu Yueh)、蔡嘉哲(Gregory J. Tsay)、(Wen-Ching Chiu)、(Yi-Chin Yang)、(Alex Yang-Hao Yu)*、洪慧珊(Huey-Shan Hung)*,Cytotoxicity and Cellular Uptake Capacity of a Berberine-Loaded Nanogold/Collagen Drug Delivery System in Lung Cancer,COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2024 Jul,702():134961 | 2024 . 07 |
2 | 蔡嘉哲(Gregory J. Tsay)、(Moncef Zouali)*,Cellular pathways and molecular events that shape autoantibody production in COVID-19,JOURNAL OF AUTOIMMUNITY,2024 Jul,147(103276): | 2024 . 07 |
3 | (Kausalya Neelavara Makkithaya)、(Nirmal Mazumder)、王韋勳(Wang,Wei-Hsun)、(Wei-Liang Chen)、陳明琪(CHEN, MING-CHI)、李明心(Lee, Ming-Xin)、(Chin-Yu Lin)、葉詠薷(Yung-Ju Yeh)、蔡嘉哲(Gregory J. Tsay)、(Sitaram Chopperla)、(Krishna Kishore Mahato)、(Fu-Jen Kao)、卓冠宇(Zhuo, Guan-Yu)*,Investigating cartilage-related diseases by polarization-resolved second harmonic generation (P-SHG) imaging,APL Bioengineering,2024 Jun,8(2):1-12 | 2024 . 06 |
4 | 藍忠亮(Joung-Liang Lan)、張詩欣(Shih-Hsin Chang)、蔡嘉哲(Gregory J. Tsay)、陳得源(Der-Yuan Chen)、趙玉華(Yu-Hua Chao)、李如璧(Ju-Pi Li)*,Immune cell profiles of idiopathic inflammatory myopathy patients expressed anti-aminoacyl tRNA synthetase or anti-melanoma differentiation-associated gene 5 autoantibodies,BMC IMMUNOLOGY,2023 Sep,24(1):33 | 2023 . 09 |
5 | 侯甫葦(Pu-Wei Hou)、劉軒誌(Shan-Chi Liu)、蔡嘉哲(Gregory J. Tsay)、張永勳(Yuan-Shiun Chang)、黃慧琪(Hui-Chi Huang)、湯智昕(Chih-Hsin Tang)*、張恒鴻(Hen-Hong Chang)*,High-dose Tiger-Gian formula protects the knee joint from surgically induced osteoarthritis in rats,International Journal of Rheumatic Diseases,2023 Feb,26(2):316-326 | 2023 . 02 |
6 | 顏加豪(Jia-hau Yen)、黃暐㨗(Wei-Chieh Huang)、林淑卿(Shu-Ching Lin)、黃怡紋(Yi-Wen Huang)、邱琬婷、蔡嘉哲(Gregory J. Tsay)、洪明奇(Mien-Chie Hung)*、黃升騰(Sheng-Teng Huang)*,Metabolic remodeling in tumor-associated macrophages contributing to antitumor activity of cryptotanshinone by regulating TRAF6-ASK1 axis,Molecular Therapy-Oncolytics,2022 Jun,22(26):158-174 | 2022 . 06 |
7 | 侯甫葦(Pu-Wei Hou)、劉軒誌(Shan-Chi Liu)、蔡嘉哲(Gregory J. Tsay)、湯智昕(Chih-Hsin Tang)*、張恒鴻(Hen-Hong Chang)*,The Traditional Chinese Medicine “Hu-Qian-Wan” Attenuates Osteoarthritis-Induced Signs and Symptoms in an Experimental Rat Model of Knee Osteoarthritis,Evidence-based Complementary and Alternative Medicine,2022 Jan,2022(5367494):1-10 | 2022 . 01 |
8 | (Li-Wei Hsiao)、蔡嘉哲(Jia-Zer Tsay)、(Mei-Chin Mong)、(Wen-Hu Liu)、殷湄晶(Mei-chin Yin)*,Aqueous extract prepared from steamed red Amaranth (Amaranthus gangeticus L.) leaves protected human lens cells against high glucose induced glycative and oxidative stress,JOURNAL OF FOOD SCIENCE,2021 Aug,86(8):3686-3697 | 2021 . 08 |
9 | 蔡嘉哲(Jia-Zer Tsay)、(Shin-Yi Lin)、李雅珍(Chien-Yu Li)、毛正倫(Jeng-Leun Mau)、蔡淑瑤(Shu-Yao Tsai)*,Comparison of Single and Combined Use of Ergothioneine, Ferulic Acid, and Glutathione as Antioxidants for the Prevention of Ultraviolet B Radiation-Induced Photoaging Damage in Human Skin Fibroblasts,Processes,2021 Jul,9(7):1204 | 2021 . 07 |
10 | 蔡嘉哲(Jia-Zer Tsay)、(Yu-Ta Lin)、徐嘉宏(Chia-Hong Hsu)、唐烽堯、郭悅雄(Yueh-Hsiung Kuo)、趙哲毅(Che-Yi Chao)*,Adlay hull extracts attenuate β-amyloid-induced neurotoxicity and oxidative stress in PC12 cells through antioxidative, anti-inflammatory, and antiapoptotic activities.,Biochemistry and Biophysics Reports,2021 May,18(26): | 2021 . 05 |
11 | (Ivan T. Lee)、(Tsuguhisa Nakayama)、(Chien-Ting Wu5)、(Yury Goltsev)、(Sizun Jiang)、(Phillip A. Gall)、(Chun-Kang Liao)、施亮均(Liang-Chun Shih)、(Christian M. Schurch)、(David R. McIlwain)、(Pauline Chu)、(Nicole A. Borchard)、(David Zarabanda)、(Sachi S. Dholakia)、(Angela Yang)、(Dayoung Kim)、(Han Chen)、(Tomoharu Kanie)、林嘉德(Chia-Der Lin)、蔡銘修(Ming-Hsui Tsai)、(Katie M. Phillips)、(Raymond Kim)、(Jonathan B. Overdevest)、(Matthew A. Tyler)、(Carol H. Yan)、林志峰(Chih-Feng Lin)、(Yi-Tsen Lin)、包大靝(Da-Tian Bau)、蔡嘉哲(Jia-Zer Tsay)、(Zara M. Pate)、鄒永恩(Yung-An Tsou)、(Alexandar Tzankov)、(Matthias S. Matter)、戴志展(Chih-Jaan Tai)、(Te-Huei Yeh)、(Peter H. Hwang)、(Garry P. Nolan)*、(Jayakar V. Nayak)、(Peter K. Jackson),ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs,Nature Communications,2020 Oct,11(1): | 2020 . 10 |
12 | 施亮均(Liang-Chun Shih)、謝華欣(Hsieh Hua Hsin)、蔡嘉哲(Jia-Zer Tsay)、(Ivan T. Lee)、鄒永恩(Yung-An Tsou)、林橙莉(Cheng-Li Lin)、沈德群(Shen, Te-Chun)*、包大靝(Da-Tian Bau)、戴志展(Chih-Jaan Tai)、林嘉德(Chia-Der Lin)、蔡銘修(Ming-Hsui Tsai),Chronic Rhinosinusitis and Premorbid Autoimmune Diseases: A Population-based Case-control Study,Scientific Reports,2020 Oct,10(1):18635 | 2020 . 10 |
13 | 彭心儀(Hsin Yi-Peng)、陳世堯(Shih-Yao Chen)、蕭士鴻(Shih-Hong SIAO)、蔡菁華(Jinghua Tsai CHANG)、薛婷尹(Xue, Ting-Yin)、李怡萱(Yi-Hsuan LEE)、詹明修(Ming-Shiou JAN)、蔡嘉哲(Jia-Zer Tsay)*、ZOUALI MOHAM(ZOUALI MOHAMED MONCEF)*,Targeting a cysteine protease from a pathobiont alleviates experimental arthritis,ARTHRITIS RESEARCH & THERAPY,2020 May,22(1):114 | 2020 . 05 |
14 | 蔡淑瑤(Shu-Yao Tsai)、蔡嘉哲(Jia-Zer Tsay)、林駿憑(Chung-Ping Lin)*,Assessment of Melting Kinetics of Sugar-Reduced Silver Ear Mushroom Ice Cream under Various Additive Models,Applied Sciences-Basel,2020 Feb,10(8): | 2020 . 02 |
15 | 吳怡瑩*、(CHIN-TUNG HSIEH)、蔡嘉哲(Jia-Zer Tsay)、高榮達(Jung-Ta Kao)、(Ying?Ming Chiu)*、(Dong?Chen Shieh)、(Yi?Ju Lee),Recruitment of CCR6+ Foxp3+ regulatory gastric infiltrating lymphocytes in Helicobacter pylori gastritis.,HELICOBACTER,2019 Feb,24(1): | 2019 . 02 |
16 | (Huey-En Tzeng)、黃柏豪(Po-Hao Huang)、蔡俊灝(Chun-Hao Tsai)、蔡嘉哲(Jia-Zer Tsay)、(Yi-Ju Lee)、黄琮竣(HUANG,TSURNG-JUHN)、(Tzu-Hung Lin)、(Ying-Ming Chiu)、吳怡瑩*,Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis,Scientific Reports,2018 Jul,8(1):11190 | 2018 . 07 |
17 | 蔡俊灝(Tsai, Chun-Hao)、(Ming-Hua Hsu)、黃柏豪(Huang, Po-Hao)、(Chin-Tung Hsieh)、(Chiu YM)、(Shieh DC)、(Lee YJ)、蔡嘉哲(Tsay, Gregory J)、吳怡瑩(Wu, Yi-Ying)*,A Paeonol derivative, YPH-PA3 promotes the differentiation of monocyte/macrophage lineage precursor cells into osteoblasts and enhances their autophagy.,European Journal of Pharmacology,2018 May,S0014-2999(18):30286-3 | 2018 . 05 |
18 | 蔡嘉哲(Jia-Zer Tsay)、(Moncef Zouali)*,The Interplay Between Innate-Like B Cells and Other Cell Types in Autoimmunity,Frontiers in Immunology,2018 May,9():1064 | 2018 . 05 |
19 | Huey-En Tzen、蔡俊灝(Tsai, Chun-Hao)、侯庭鏞(Ho, Tin-Yun)、(Chin-Tung Hsieh)、周聖杰(Chou, Shen-Chieh)、(Yi-Ju Lee)、蔡嘉哲(Tsay, Gregory J)、黃柏豪(Huang, Po-Hao)、吳怡瑩(Wu, Yi-Ying)*,Radix Paeoniae Rubra stimulates osteoclast differentiation by activation of the NF-κB and mitogen-activated protein kinase pathways,BMC Complementary and Alternative Medicine,2018 Apr,18(132): | 2018 . 04 |
20 | (YING-MING CHIU)、(CHUNG-LIN TSAI)、高榮達(Kao, Jung-Ta)、(CHIN-TUNG HSIEH)、(DONG-CHEN SHIEH)、(YI-JU LEE)、蔡嘉哲(Tsay, Gregory J)、鄭庚申(Cheng, Ken-Sheng)、吳怡瑩(Wu, Yi-Ying)*,PD-1 and PD-L1 Up-regulation Promotes T-cell Apoptosis in Gastric Adenocarcinoma,ANTICANCER RESEARCH,2018 Apr,38(4):2069-2078 | 2018 . 04 |
21 | (CHUNG-LIN TSAI)、(YING-MING CHIU)、侯庭鏞(Ho, Tin-Yun)、(CHIN-TUNG HSIEH)、(DONG-CHEN SHIEH)、(YI-JU LEE)、蔡嘉哲(Tsay, Gregory J)、吳怡瑩(Wu, Yi-Ying)*,Gallic Acid Induces Apoptosis in Human Gastric Adenocarcinoma Cells,ANTICANCER RESEARCH,2018 Apr,38(4):2057-2067 | 2018 . 04 |
22 | (Chung-Lin Tsai)、(Ying-Ming Chiu)、(Yi-Ju Lee)、(Chin-Tung Hsieh)、(Dong-Chen Shieh)、蔡嘉哲(Tsay, Gregory J)、包大靝(Bau, Da-Tian)、吳怡瑩(Wu, Yi-Ying)*,Interleukin 32 plays an essential role in human calcified aortic valve cells,EUROPEAN CYTOKINE NETWORK,2018 Mar,29(1):36-47 | 2018 . 03 |
23 | (Kuang-Hui YU)、陳得源(Der-Yuan Chen)、(Jiunn-Horng CHEN)、(Shih-Yang CHEN)、(Shyh-Ming CHEN)、(Tien-Tsai CHENG)、(Song-Chou HSIEH)、(Tsu-Yi HSIEH)、(Pai-Feng HSU)、(Chang-Fu KUO)、(Mei-Chuan KUO)、(Hing-Chung LAM)、(I-Te LEE)、(Toong-Hua LIANG)、(Hsiao-Yi LIN)、(Shih-Chang LIN)、(Wen-Pin TSAI)、蔡嘉哲(Jia-Zer Tsay)、魏正宗(Wei,Cheng-Chung)、(Chung-Han YANG)、(Wen-Chan TSAI)*,Management of gout and hyperuricemia: Multidisciplinary consensus in Taiwan,International Journal of Rheumatic Diseases,2018 Jan,21(4):772-787 | 2018 . 01 |
24 | 黃春明(Huang, Chung-Ming)、陳宣如(Hsuan-Ju Chen)、黃柏豪(Huang, Po-Hao)、蔡嘉哲(Tsay, Gregory J)、藍忠亮(Lan, Joung-Liang)、宋鴻樟(Sung, Fung-Chang)*,Retrospective Cohort Study on Risk of Hearing Loss in Patients with Rheumatoid Arthritis Using Claims Data,BMJ Open,2018 Jan,8(1):e018134.-e018134. | 2018 . 01 |
25 | 楊凱介(Yeo Kai Jieh)、張詩欣(Shih-Hsin Chang)、黃柏豪(Po-Hao Huang)、蔡嘉哲(Jia-Zer Tsay)、黃春明(Chung-Ming Huang)、陳俊宏(Jiunn-Horng Chen)、洪偉哲(Wei-Jhe Hong)、吳柏樟(Po-Chang Wu)、藍忠亮(Joung-Liang Lan)*,Clinical Image: Diencephalon and isolated unilateral abducen nerve palsy in neuro-Behçet's disease- a rare manifestation,中華民國風濕病雜誌,2017 Dec,31(2):31-32 | 2017 . 12 |
26 | (Zsuzsa Szondy)*、(Ilma Korponay-Szabo)、(Robert Kiraly)、(Zsolt Sarang)、蔡嘉哲(Tsay, Gregory J),Transglutaminase 2 in human diseases,BioMedicine,2017 Sep,7(3):1-13 | 2017 . 09 |
27 | 藍忠亮(Joung-Liang Lan)、曾鈞宏(Chun-Hung Tseng)、陳俊宏(Jiunn-Horng Chen)*、鄭奇浲(Cheng, Chi-Fung)、梁文敏(Wen-Miin Liang)、蔡嘉哲(Gregory J Tsay),Reduced risk of all-cancer and solid cancer in Taiwanese patients with rheumatoid arthritis treated with etanercept, t TNF-alfa inhibitor,MEDICINE,2017 Feb,96(7): | 2017 . 02 |
28 | (Ching-Chyuan SU)、(Tzu-Rong SU)、(Ji-Ching LAI)、蔡嘉哲(Gregory J Tsay)*、(Hung-Ke LIN)*,Elevated transglataminase-2 expression in the epidermis of psoriatic skin and its role in the skin lesion development,JOURNAL OF DERMATOLOGY,2017 Feb,():2016年接受 | 2017 . 02 |
29 | 黃建中(Chien-Chung Huang)、藍忠亮(Joung-Liang Lan)、蔡嘉哲(Gregory J Tsay)、黃春明(Chung-Ming Huang)、陳俊宏(Jiunn-Horng Chen)、黃柏豪(Po-Hao Huang)、吳柏樟(Po-Chang Wu)、洪偉哲(Wei-Jhe Hong),Clinical Images: recurrent spontaneous intramuscular hematoma by acquired coagulation factor XIII deficiency in an elder patient with systemic lupus erythematosus,中華民國風濕病雜誌,2016 Dec,30(2):80-81 | 2016 . 12 |
30 | 藍振嘉(Chen-Chia Lan)、曾鈞宏(Chun-Hung Tseng)、陳俊宏(Jiunn-Horng Chen)*、藍忠亮(Joung-Liang Lan)、王昱喬(Yu-Chiao Wang)、蔡嘉哲(Gregory J Tsay)、許重義(Chung Y. Hsu),Increased risk of a suicide event in patients with primary fibromyalgia and fibromyalgia patients with concomitant comorbidities. A nationwide population-based cohort study,MEDICINE,2016 Nov,(): | 2016 . 11 |
31 | (Chi Chiu Mok)、(Hoon Suk Cha)、(Rudy Hidayat)、(Lan Thi Ngoc Nguyen)、(Emmanuel C. Perez)、(veendran Ramachandran)、蔡嘉哲(Gregory J Tsay)、(Dae Hyun Yoo)*,The importance of assessment and management of morning stiffness in Asian patients with rheumatoid arthritis: Recommendations from an expert panel,International Journal of Rheumatic Diseases,2016 Jan,(19):30-37 | 2016 . 01 |
32 | (Wen-Nan Huang)、(Tim K. Tso)、蔡嘉哲(Gregory J Tsay)*,Impaired transglutaminase 2 expression in patients with systemic lupus erythematosus.,中華民國風濕病雜誌,2016 ,(30):41-47 | 2016 . |
33 | (Moncef Zouali)*、蔡嘉哲(Gregory J Tsay),Developing Connections among B Lymphocytes and Deregulated Pathways in Autoimmunity,MOLECULAR MEDICINE,2016 ,(): | 2016 . |
34 | 黃文男(Wen-Nan Huang)、左克強(Tim K. TSO)、HsiaoChih Wu(Hsiao-Chih WU)、Hsiu-Fen YAN(Hsiu-Fen YANG)、蔡嘉哲(Gregory J Tsay)*,Impaired phagocytosis of apoptotic cell material in serologically active clinically quiescent patients with systemic lupus erythematosis.,International Journal of Rheumatic Diseases,2015 Dec,(): | 2015 . 12 |
35 | 黃建中(Chien-Chung Huang)、黃柏豪(Po-Hao Huang)、陳俊宏(Jiunn-Horng Chen)*、藍忠亮(Joung-Liang Lan)、蔡嘉哲(Gregory J Tsay)、林孝義、曾鈞宏(Chun-Hung Tseng)、林橙莉、許重義(Chung Y. Hsu),An indepentent risk of gout on the development of deep vein thrombosis and pulmonary embolism : a nationwide, population-based cohort study,MEDICINE,2015 Dec,94(51):e2140 | 2015 . 12 |
36 | 洪偉哲(Wei-Jhe Hong)、藍忠亮(Joung-Liang Lan)*、蔡嘉哲(Jia-Zer Tsay)、黃春明(Chung-Ming Huang)、陳俊宏(Jiunn-Horng Chen)、黃柏豪(Po-Hao Huang)、黃建中(Chien-Chung Huang)、吳柏樟(Po-Chang Wu),Behcet's disease complicated with intracardiac thrombus,中華民國風濕病雜誌,2015 Dec,29(2):44-45 | 2015 . 12 |
37 | 陳俊宏(Jiunn-Horng Chen)*、藍忠亮(Joung-Liang Lan)、鄭奇浲(Chi-Fung Cheng)、梁文敏(Wen-Miin Liang)、林孝義(Hsiao Yi Lin)、蔡嘉哲(Gregory J Tsay)、葉文婷(Wen Ting Yeh)、潘文涵(Wen-Harn Pan),Effect of Urate-Lowering Therapy ob All-Cause and Cardiovascular Mortality in Hyperuricemic Patients without Gout : A Case-Matched Cohort Study,PLoS One,2015 Dec,10(12):e0145193 | 2015 . 12 |
38 | 何茂旺(Mao-Wang Ho)、曾鈞宏(Chun-Hung Tseng)、陳俊宏(Jiunn-Horng Chen)*、藍忠亮(Joung-Liang Lan)、黃建中(Chien-Chung Huang)、莫之欣、許重義(Chung Y. Hsu)、蔡嘉哲(Gregory J Tsay),Chronic osteomyelitis as a risk factor for development of rheumatoid arthritis : a nationwide, population-based, cohort study,CLINICAL RHEUMATOLOGY,2015 Jul,(): | 2015 . 07 |
39 | 顏家豪(Jia-Hao Yen)、(Ling-Chung Lin)、(Meng-Chi Chen)、(Zsolt Sarang)、(Put-Ying Leung)、(I-Chang Chang)、(Jung-Dong Hsu)、陳俊宏(Jiunn-Horng Chen)、(You-Fan Hsien)、(Anna Pallai)、(Krisztina Koroskenyi)、(Zsuzsa Szondy)、蔡嘉哲(Gregory J Tsay)*,The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in self-limitation of monosodium urate crystal-induced inflammation by upregulating TGF-beta1,ARTHRITIS RESEARCH & THERAPY,2015 Mar,16(65): | 2015 . 03 |
40 | 顏嘉豪(Yen, Jia-Hau)、楊登傑(Yang, Deng-Jye)、(Chen, Meng-Chi;)、(Hsieh, Yu-Fan)、(Sun, Yu-Shu;)、蔡嘉哲(Gregory J Tsay)*,Glycine tomentella Hayata inhibits IL-1beta and IL-6 production, inhibits MMP-9 activity, and enhances RAW264.7 macrophage clearance of apoptotic cells,JOURNAL OF BIOMEDICAL SCIENCE,2010 Oct,17():83-9 | 2010 . 10 |
41 | 林昭田(Lin, Jau-Tien;)、劉世詮(Liu, Shih-Chuan)、蔡嘉哲(Gregory J Tsay)、楊登傑(Yang, Deng-Jye)*,Composition of flavonoids and phenolic acids in Glycin tomentella Hayata cultivated in various soils,Food Chemistry,2010 Aug,121(3):659-665 | 2010 . 08 |
研討會論文
研討會論文/Conference Papers (發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目) |
日期 | |
1 | ,臺灣皮膚科醫學會 一百一十三年度第四次中區聯合討論會,中山醫學大學 正心樓 3 樓0321 教室,2024.12.22~2024.12.22,The Journey from Darkness to Light: My Experience with Melanoma | 2024 . 12 |
2 | Crucial Role of MERTK-Mediated Efferocytosis in Hydroxychloroquine's Anti-Inflammatory Effects in Pristane-Induced Lupus Mice,2024年中華民國風濕病醫學會年會,新竹喜來登大飯店3F,2024.12.13~2024.12.15, | 2024 . 12 |
3 | ,The 9th Federation of Immunological Societies of Asia-Oceania Congress (FIMSA 2024),Taipei International Convention Center (TICC),2024.10.23~2024.10.27,The Journey from Darkness to Light: My Experience with Melanoma | 2024 . 10 |
4 | Hydroxychloroquine and its derivative enhance efferocytosis and modulate the gut microbiome in pristane-induced lupus mice,IMMUNOLOGY 2024 TM,CHICAGO, ILLINOIS,2024.05.03~2024.05.07, | 2024 . 05 |
5 | ,2024 生技研發成果媒合會,台大醫院國際會議中心 402AB,2024.04.16~2024.04.16,精準診斷類風濕性關節炎 | 2024 . 04 |
6 | ,臺灣皮膚科醫學會第49屆年會 暨歐亞皮膚性病學(EAAD) 第8屆研討會,高雄展覽館,2023.12.08~2023.12.10, | 2023 . 12 |
7 | 研發一種新型單株抗體治療類風濕性關節炎,2023 NBRP Pitch Day 國家生技研究園區─全國 生醫轉譯選拔媒合會暨園區服務推廣說明會,國家生技研究園區,2023.12.14~2023.12.15, | 2023 . 12 |
8 | Modulating Efferocytosis via Mertk and Axl Expression Using CRISPR/Cas9,中華民國免疫學會2023年第45次會員大會暨學術研討會,中國醫藥大學 水湳校區,2023.10.21~2023.10.22, | 2023 . 10 |
9 | Amelioration of Collagen-Induced Arthritis in Rats by a Monoclonal Antibody against the Novel Epitope of Cysteine Protease from P. gingivalis,IMMUNOLOGY 2023 TM,Washington,2023.05.11~2023.05.15, | 2023 . 05 |
10 | Autoantibodies Against a Specific 25-mer Peptide from P. Gingivalis Are Present in Sera of Patients with Rheumatoid Arthritis and Early Arthritis,2022 ACR CONVERGENCE,NJ USA,2022.11.10~2022.11.14, | 2022 . 11 |
11 | 以一種新穎的單株抗體治療類風濕性關節炎動物模式,2022年中華民國風濕病醫學會年會,台北萬豪酒店,2022.10.14~2022.10.16, | 2022 . 10 |
12 | A specific 25-mer peptide from the cysteine protease of P. gingivalis is the epitope of humoral immune response in rheumatoid arthritis,IMMUNOLOGY 2022TM,Oregon Convention Center Portland, Oregon,USA,2022.05.06~2022.05.10, | 2022 . 05 |
13 | A cysteine protease of P. gingivalis is the target of autoantibody in rheumatoid arthritis,2021社團法人中華民國風濕病醫學會會員大會暨學術研討會,採全線上會議,2021.10.30~2021.10.31, | 2021 . 10 |
14 | 動脈血管鈣化病變發生在一位帶有抗磷脂質自體抗體和反覆腳多處潰瘍的病人,2020社團法人中華民國風濕病醫學會會員大會暨學術研討會,台北新板希爾頓酒店,2020.10.31~2020.11.1 , | 2020 . 10 |
15 | Hydroxychloroquine enhances efferocytosis and inhibits IL-6 and TNF-α productions through upregulating both Gas6/Axl and MFG-E8/TG2 Signaling pathways in Pristine-induced lupus mice,The American Association of Immunologists,線上會議,2020.05.8 ~2020.05.12, | 2020 . 05 |
16 | 探討乾癬致病機轉Explore the pathogenesis of psoriasis,2020年中國醫藥大學暨亞洲大學生物科技研討會,中國醫藥大學,2020.05.12~2020.05.12, | 2020 . 05 |
17 | Clinical Images: Efficacy and safety of tofacitinib in the treatment of alopecia totalis with chronic hepatitis B virus infection,中華民國風濕病醫學會2019年會,台南大員皇冠酒店2樓宴會廳,2019.12.13~2019.12.15, | 2019 . 12 |
18 | 36H 抑制蝕骨細胞與動物實驗,2019年中亞聯大生物科技研討會,亞洲大學,2019.05.24~2019.05.24, | 2019 . 05 |
19 | Transglutaminase-2 在人體主動脈瓣膜細胞鈣化中所扮演的角色,2019年中亞聯大生物科技研討會,亞洲大學,2019.05.24~2019.05.24, | 2019 . 05 |
20 | ACTIN-K抑制蝕骨細胞促進造骨細胞與動物實驗,2019年中亞聯大生物科技研討會,亞洲大學,2019.05.24~2019.05.24, | 2019 . 05 |
21 | Hydroxychloroquine Increases Efferocytosis via Modulating both Mertk-GAS6/PROS and Integrin-TG2-Mfge8 Pathway,21st Asia Pacific League of Associations for Rheumatology Congress in conjunction with the Australian Rheumatology Association (APLAR-ARA 2019),Brisbane, Australia,2019.04.08~2019.04.11, | 2019 . 04 |
22 | THE PROTECTIVE EFFECTS OF VACCINATION WITH PORPHYROMONAS GINGIVALIS AND RGPA DOMAINS IN RATS WITH COLLAGEN-INDUCED ARTHRITIS,The Federation of Immunological Societies of Asia-Oceania Congress,Bangkok,2018.11.10~2018.11.13, | 2018 . 11 |
23 | Screening natural products and drugs for the therapy of autoimmune diseases by efferocytosis,Asia Pacific League of Associations for Rheumatology,Kaohsiung,2018.09.06~2018.09.09, | 2018 . 09 |
24 | 槲皮素對巨噬細胞清除凋亡細胞之能力及相關機制探討,第 44 屆營養年會暨學術研討會,輔仁大學國璽樓一樓國際會議廳,2018.05.25~2018.05.26, | 2018 . 05 |
25 | Resveratrol increases efferocytosis via both Mertk-GAS6/PROS and Integrin-TG2-Mfge8 pathway,IMMUNOLOGY 2018TM,Austin,2018.03.04~2018.03.08, | 2018 . 03 |
26 | Hearing loss associated with rheumatoid arthritis: a nationwide retrospective cohort study,中華民國風濕病醫學會第35 週年年會,台中林酒店,2017.09.08~2017.09.10, | 2017 . 09 |
27 | Anti-FHL1 Autoantibody in Patients with Idiopathic Inflammatory Myopathy,2017年中華民國風濕病醫學會會員大會暨學術研討會,台中林酒店,2017.09.08~2017.09.10, | 2017 . 09 |
28 | Hypothyroidism association with Rheumatoid arthritis : a nationwide cohort study,中華民國風濕病醫學會第35 週年年會,台中林酒店,2017.09.08~2017.09.10, | 2017 . 09 |
29 | Hospitalized patients with fractures and risk for incident rheumatoid arthritis:a nationwide population-based cohort study,中華民國風濕病醫學會第35週年年會,台中林酒店,2017.09.08~2017.09.10, | 2017 . 09 |
30 | Antibody to HA4 of gingipain of Porphyromonas gingivalis is a possible biomarker for rheumatoid arthritis,Immunology 2017,Washington, D.C.,2017.05.12~2017.05.16, | 2017 . 05 |
31 | Anti-mitochondrial antibody negative primary biliary cirrhosis and autoimmune hepatitis overlap syndrome in a patient with systemic lupus erythematosus: a case report,中華民國風濕病醫學會第34週年年會,新竹喜來登飯店,2016.10.21~2016.10.23, | 2016 . 10 |
32 | Salivary Gland Ultrasonography : Compare Sjogren’s Syndrome with Other Diseases That Involved Salivary Gland,中華民國風濕病醫學會第34週年年會,新竹喜來登飯店,2016.10.21~2016.10.23, | 2016 . 10 |
33 | Infectious Agents and Autoimmunity,International Advanced Immunology Summer School,中國醫藥大學、南投雲品酒店,2016.08.13~2016.08.14, | 2016 . 08 |
34 | Tg2 Restraints Monosodium Urate Crystal-Mediated Inflammation Via Elevated Induction of TGF-Beta1,6th Congress of FIMSA - FIMSA 2015,Sands Expo and Convention Centre, Singapore,2015.06.30~2015.07.03, | 2015 . 06 |
專書
專書/Books (作者,書名,出版商,出版日期) |
日期 | |
1 | Pei-Lun Chou(Pei-Lun Chou)、蔡嘉哲(Gregory J Tsay),Encyclopedia of Cancer,,2015.1 | 2015 . 01 |
研究計畫
研究計畫/Research Grant (研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,計畫期間) |
日期 | |
1 | 個別型,NSTC 113-2314-B-039-006,,科技部,以CRISPR-Cas9增強巨噬細胞MerTK表現及其臨床應用(2/3),2024.8.1~2025.7.31 | 2024 . 08 |
2 | 個別型,NSTC 113-2622-B-039-002,,科技部,開發類風濕性關節炎的一種新穎性單株抗體(Il),2024.5.1~2024.9.30 | 2024 . 05 |
3 | 個別型,NSTC 112-2622-B-039-007,,科技部,開發類風濕性關節炎的一種新穎性單株抗體(I),2023.10.1~2024.4.30 | 2023 . 10 |
4 | 個別型,NSTC 112-2314-B-039-023,,科技部,以CRISPR-Cas9增強巨噬細胞MerTK表現及其臨床應用(1/3),2023.8.1~2024.7.31 | 2023 . 08 |
5 | 個別型,NSTC 112-2314-B-039-008,戴志展(Chih-Jaan Tai)、蔡嘉哲(Gregory J. Tsay)、黃得韻(NG TEIK YING),科技部,探討轉麩醯胺酶-2在慢性鼻竇炎合併鼻息肉與不合併鼻息肉的角色(2/3),2023.8.1~2024.7.31 | 2023 . 08 |
6 | 個別型,MOST 111-2314-B-039-065,戴志展(Chih-Jaan Tai)、蔡嘉哲(Gregory J. Tsay)、黃得韻(NG TEIK YING),科技部,探討轉麩醯胺酶-2在慢性鼻竇炎合併鼻息肉與不合併鼻息肉的角色(1/3),2022.8.1~2023.7.31 | 2022 . 08 |
7 | 學生參與計畫,CMU111-SR-122,,本校(含附醫),探討諾卡酮於細胞激素誘導滑膜細胞發炎反應之調控角色,2022.8.1~2023.2.28 | 2022 . 08 |
8 | 個別型,MOST 111-2314-B-039-037,,科技部,研究hydroxychloroquine(羥氯奎寧)治療風濕病之作用機轉、引起視網膜病變機轉及其新衍生物之研究,2022.8.1~2023.7.31 | 2022 . 08 |
9 | 個別型,MOST 110-2622-B-039-002,邵耀華,科技部,精準性檢驗類風濕性關節炎之診斷套組(II),2021.8.1~2022.3.31 | 2021 . 08 |
10 | 個別型,MOST 110-2314-B-039-055,,科技部,研究嘌呤P2X7接受器、轉麩醯胺酶-2與鈣離子在乾癬之角色(3/3),2021.8.1~2022.7.31 | 2021 . 08 |
11 | 個別型,MOST 109-2622-B-039-003,邵耀華,科技部,精準性檢驗類風濕性關節炎之診斷套組(I),2020.10.1~2021.7.31 | 2020 . 10 |
12 | 個別型,DMR-110-010,張恒鴻(Hen-Hong Chang)、蔡嘉哲(Jia-Zer Tsay)、黃春明(Chung-Ming Huang)、蔡俊灝(Chun-Hao Tsai)、洪誌鴻(Chi-Horng Horng),附醫院內計畫,退化性膝關節炎患者服用中藥複方TGF之良導絡變化,2020.8.1~2021.7.31 | 2020 . 08 |
13 | 個別型,DMR-110-056,蔡嘉哲(Jia-Zer Tsay)、戴志展(Chih-Jaan Tai)、黃得韻(Ng Teik Ying),附醫院內計畫,探討轉麩醯氨酶-2在慢性鼻竇炎合併鼻息肉與不合併鼻息肉的角色,2020.8.1~2021.7.31 | 2020 . 08 |
14 | 個別型,MOST 109-2314-B-039-052,,科技部,研究嘌呤P2X7接受器、轉麩醯胺酶-2與鈣離子在乾癬之角色(2/3),2020.8.1~2021.7.31 | 2020 . 08 |
15 | 個別型,MOST 108-2320-B-039-007-,張恒鴻(Hen-Hong Chang)、蔡嘉哲(Jia-Zer Tsay)、李德彥(Lee, Der-Yen),科技部,中藥複方TGF治療退化性膝關節炎之隨機雙盲臨床試驗,2019.8.1~2020.7.31 | 2019 . 08 |
16 | 個別型,MOST 108-2314-B-039-019-,,科技部,研究嘌呤P2X7接受器、轉麩醯胺酶-2與鈣離子在乾癬之角色(1/3),2019.8.1~2020.7.31 | 2019 . 08 |
17 | 個別型,MOST 108-2314-B-039-019-,,科技部,研究嘌呤P2X7接受器、轉麩醯胺酶-2與鈣離子在乾癬之角色(1/3),2019.8.1~2020.7.31 | 2019 . 08 |
18 | 個別型,DMR-109-041,蔡嘉哲(Jia-Zer Tsay)、黃得韻(Ng Teik Ying)、施亮均(Liang-Chun Shih),附醫院內計畫,Transglutaminase 2在過敏型慢性鼻竇炎與非過敏型慢性鼻竇炎之角色,2019.8.1~2020.7.31 | 2019 . 08 |
19 | 個別型,DMR-109-041,蔡嘉哲(Jia-Zer Tsay)、施亮均(Liang-Chun Shih)、黃得韻(Ng Teik Ying),附醫院內計畫,Transglutaminase 2 在過敏型慢性鼻竇炎與非過敏型慢性鼻竇炎之角色,2019.8.1~2020.7.31 | 2019 . 08 |
20 | 個別型,CMU107-TU-02,,本校(含附醫),牙周病與類風濕性關節炎之關係及開發診斷之生物標誌,2019.6.1~2020.7.31 | 2019 . 06 |
21 | 個別型,MOST 107-2314-B-039-050-,,科技部,以吞噬凋亡細胞能力研發抗發炎藥物、肥胖、及乾癬,2018.8.1~2019.7.31 | 2018 . 08 |
22 | 個別型,DMR-108-036,蔡嘉哲(Jia-Zer Tsay)、戴志展(Chih-Jaan Tai)、黃得韻(Ng Teik Ying),附醫院內計畫,不同內因型鼻竇炎合併有無鼻息肉與功能性鼻竇內視鏡手術之預後相關性,2018.8.1~2019.7.31 | 2018 . 08 |
23 | 個別型,MOST 106-2314-B-039-040-,,科技部,研究類風濕性關節炎及牙周病病人血清中P.gingivalis抗體之抗原接會點及研究P.gingivalis之hemagglutinin區域在動物模式之免疫應用,2017.8.1~2018.7.31 | 2017 . 08 |
24 | 臨床試驗與研究計畫,CMUH105-REC3-133,蔡嘉哲(Tsay, Gregory J)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong),附醫廠商計畫,一項隨機分配、雙盲、安慰劑和活性藥物對照、多中心、第三期試驗,在罹患中至重度活動性類風濕性關節炎,且未曾接受Methotrexate (MTX) 療法的受試者中,評估單獨使用Filgotinib 與併用MTX 52 週的療效及安全性,2017.1.1~2017.12.31 | 2017 . 01 |
25 | 臨床試驗與研究計畫,CMUH105-REC1-149,蔡嘉哲(Tsay, Gregory J)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong),附醫廠商計畫,一項隨機分配、雙盲、安慰劑和活性藥物對照、多中心、第三期試驗,在罹患中至重度活動性類風濕性關節炎,且對 Methotrexate 療效反應不足的受試者中,評估 Filgotinib 與 Methotrexate 併用 52 週的療效及安全性,2017.1.1~2017.12.31 | 2017 . 01 |
26 | 個別型,MOST 106-2911-I-039-501,,科技部,探討未正常清除之凋亡細胞與肥胖及慢性發炎相關疾病之關連 (2/2),2017.1.1~2017.12.31 | 2017 . 01 |
27 | 臨床試驗與研究計畫,CMUH105-REC2-025,黃春明(Huang, Chung-Ming)、陳俊宏(Chen, Jiunn-Horng)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong)、蔡嘉哲(Tsay, Gregory J),附醫廠商計畫,Ixekizumab (LY2439821)使用於未曾接受bDMARD之放射線影像異常軸心型脊椎關節炎病患的一項多中心、隨機分配、雙盲、活性藥物與安慰劑對照16週試驗與安全性與療效的長期評估追蹤,2017.1.1~2017.12.31 | 2017 . 01 |
28 | 臨床試驗與研究計畫,CMUH106-REC3-111,黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong)、蔡嘉哲(Tsay, Gregory J),附醫廠商計畫,一項隨機、雙盲、安慰劑對照、多中心的第 2 期劑量範圍試驗,評估皮下施打 VAY736 多次劑量,用於中度至重度原發性修格連氏症候群患者的安全性和療效,2017.1.1~2017.12.31 | 2017 . 01 |
29 | 臨床試驗與研究計畫,CMUH106-REC1-029,黃建中(Chien-Chung Huang)、黃柏豪(Bo-Hau Huang)、蔡嘉哲(Tsay, Gregory J)、洪偉哲(Wei-Jhe Hong),附醫廠商計畫,一項隨機分配、對照雙盲試驗,探討 Orelvo (voclosporin) (23.7 mg,每日兩次) 用於治療活動型狼瘡性腎炎受試者,相較於安慰劑,在達到腎臟反應方面的療效及安全性,2017.1.1~2017.12.31 | 2017 . 01 |
30 | 臨床試驗與研究計畫,CMUH105-REC2-138,黃春明(Huang, Chung-Ming)、陳俊宏(Chen, Jiunn-Horng)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong)、蔡嘉哲(Tsay, Gregory J),附醫廠商計畫,以軸心型脊椎關節炎病患評估Ixekizumab (LY2439821) 療效維持情況之一項104週多中心、長期延伸試驗(包括一個雙盲、安慰劑對照40週隨機分配退出-再度治療期),2017.1.1~2017.12.31 | 2017 . 01 |
31 | 臨床試驗與研究計畫,CMUH106-REC1-058,蔡嘉哲(Tsay, Gregory J)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong),附醫廠商計畫,一項為期 12 個月的非介入性、前瞻性研究,探討 SecukInumab 和目前的標準醫療照護,對亞太及中東地區適合接受全身性治療之慢性斑塊性乾癬患者的實際療效和治療模式 (REALIA),2017.1.1~2017.12.31 | 2017 . 01 |
32 | 臨床試驗與研究計畫,CMUH105-REC3-026,黃春明(Huang, Chung-Ming)、陳俊宏(Chen, Jiunn-Horng)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong)、蔡嘉哲(Tsay, Gregory J),附醫廠商計畫,針對Baricitinib在全身紅斑性狼瘡(Systemic Lupus Erythematosus,SLE)病患的隨機分配、雙盲、安慰劑對照、平行分組、第2期試驗,2017.1.1~2017.12.31 | 2017 . 01 |
33 | 個別型,MOST 105-2314-B-039-047-,,科技部,研究牙周病致病菌Porphyromonas gingivalis之血球凝集區(Hemagglutinin domain, HA)之免疫反應在關節炎動物模式之角色,2016.8.1~2017.7.31 | 2016 . 08 |
34 | 臨床試驗與研究計畫,CMUH105-REC3-026,黃春明(Chung-Ming Huang)、陳俊宏(Jiunn-Horng Chen)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong)、蔡嘉哲(Gregory J Tsay),附醫廠商計畫,針對Baricitinib在全身紅斑性狼瘡(Systemic Lupus Erythematosus,SLE)病患的隨機分配、雙盲、安慰劑對照、平行分組、第2期試驗,2016.1.1~2016.12.31 | 2016 . 01 |
35 | 臨床試驗與研究計畫,CMUH105-REC1-043,蔡嘉哲(Gregory J Tsay)、黃春明(Chung-Ming Huang)、陳俊宏(Jiunn-Horng Chen)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong),附醫廠商計畫,一項第三期、隨機分配、雙盲之臨床試驗,比較ABT-494、Adalimumab與安慰劑於接受穩定劑量之Methotrexate(MTX)治療未獲良好控制之中重度活動性類風濕性關節炎患者之安全性與療效,2016.1.1~2016.12.31 | 2016 . 01 |
36 | 臨床試驗與研究計畫,CMUH105-REC1-061,蔡嘉哲(Gregory J Tsay)、黃春明(Chung-Ming Huang)、陳俊宏(Jiunn-Horng Chen)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong),附醫廠商計畫,一項針對具有抗腫瘤壞死因子(TNFα)藥物頑抗性之活動性放射影像軸心型脊椎關節炎受試者,評估Ustekinumab療效和安全性的第三期、多中心、隨機分配、雙盲、安慰劑對照試驗,2016.1.1~2016.12.31 | 2016 . 01 |
37 | 臨床試驗與研究計畫,CMUH105-REC2-025,黃春明(Chung-Ming Huang)、陳俊宏(Jiunn-Horng Chen)、黃柏豪(Bo-Hau Huang)、黃建中(Chien-Chung Huang)、洪偉哲(Wei-Jhe Hong)、蔡嘉哲(Gregory J Tsay),附醫廠商計畫,Ixekizumab (LY2439821)使用於未曾接受bDMARD之放射線影像異常軸心型脊椎關節炎病患的一項多中心、隨機分配、雙盲、活性藥物與安慰劑對照16週試驗與安全性與療效的長期評估追蹤,2016.1.1~2016.12.31 | 2016 . 01 |
38 | 個別型,MOST 105-2911-I-039-504,,科技部,探討未正常清除之凋亡細胞與肥胖及慢性發炎相關疾病之關連 (1/2),2016.1.1~2016.12.31 | 2016 . 01 |
39 | 臨床試驗與研究計畫,CMUH105-REC2-056,黃春明(Chung-Ming Huang)、黃柏豪(Bo-Hau Huang)、陳俊宏(Jiunn-Horng Chen)、蔡嘉哲(Gregory J Tsay)、洪偉哲(Wei-Jhe Hong)、黃建中(Chien-Chung Huang),附醫廠商計畫,一項第三期、隨機分配、雙盲之臨床試驗,針對未接受過Methotrexate (MTX)治療之中度至重度活性類風濕性關節炎患者,比較ABT-494每日一次單一療法及MTX單一療法的安全性與療效,2016.1.1~2016.12.31 | 2016 . 01 |
40 | 個別型,MOST 104-2314-B-039-057 -,藍忠亮(Joung-Liang Lan)、蔡嘉哲(Gregory J Tsay),科技部,研究MDA5在特發性炎症肌炎的免疫病理之角色,2015.12.1~2016.10.31 | 2015 . 12 |
41 | 個別型,MOST104-2314-B-039-057,蔡嘉哲(Gregory J Tsay),科技部,研究MDA5在特發性炎症肌炎的免疫病理之角色,2014.12.1~2015.10.31 | 2014 . 12 |
專利技術
專利/Patent (專利名稱,專利類別,專利國別,專利號碼,專利期間) |
日期 | |
1 | 一種類風濕關節炎自體抗體結合的胜肽及其應用,發明專利,台灣,I744777,2021.11.1~2040.1.19 | 2021 . 11 |
獲獎事蹟
獲獎/Award (獲獎名稱,給獎單位,獲獎日期) |
日期 | |
1 | 2022未來科技獎,科技部,2022.10.15 | 2022 . 10 |
2 | 2021年國家新創獎 精進續獎,財團法人生技醫療科技政策研究中心,2021.12.17 | 2021 . 12 |
3 | 中華民國風濕病醫學會第39屆學術研討會-優秀論文獎,中華民國風濕病醫學會,2021.10.31 | 2021 . 10 |
4 | 第十六屆國家新創獎,財團法人生技醫療科技政策研究中心,2019.12.6 | 2019 . 12 |