醫師介紹

Doctor Introduction

:::

醫師個人介紹

Der-Yuan Chen
Der-Yuan Chen

風濕免疫中心副院長、教授

陳得源 Der-Yuan Chen

風濕免疫中心副院長、教授
陳得源醫師為過敏科、免疫科及風濕科專科醫師,專業年資已逾40年,也榮獲臺灣風濕病學會(2023年)及亞太風濕病學會聯盟(2024年)大師獎,並曾任TCR理事長(2014-2016)。目前擔任中國附醫風濕免疫中心主任及副院長。研究領域包括自體免疫疾病(如SLE及RA)與自體發炎疾病(AOSD)免疫致病機轉、感染與免疫發炎關聯性,及標靶藥物安全性。由於SLE研究的傑出表現,獲我國免疫學會學術研究獎,參與亞太SLE診療建議(Lancet Rheumatology2022)。AOSD研究表現卓越,已發表35篇SCI論文且為風濕學教科書引用多次,於2020年獲全球前2%科學家之殊榮。截至2024年已發表262篇SCI期刊論文引用超過11,000次。
學術論文

期刊論文

期刊論文/Journal Paper
(作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄)
日期
1 陳柏谷(Po-Ku Chen)、魏秀娟(Shiow-Jiuan Wey)、陳得源(Der-Yuan Chen)*,Toward a personalized therapy of still’s disease based on immunologic endotypes: a narrative review,Expert Review of Clinical Immunology,2025 Feb,():1-12 2025 . 02
2 莫志超(Chi Chiu Mok)*、蘇晧(Ho So)、(Laniyati Hamijoyo)、(Nuntana Kasitanon)、陳得源(Der-Yuan Chen)、(Sang Cheol Bae)、(Meng Tao Li)、(Sandra Navarra)、葉逸軒(Desmond Yat Hin Yap)、(Yoshiya Tanaka),The 2024 APLAR Consensus on the Management of Lupus Nephritis,International Journal of Rheumatic Diseases,2025 Jan,28(1):e70021 2025 . 01
3 葉逸軒(Desmond Yat Hin Yap)、蘇晧(Ho So)、(Laniyati Hamijoyo)、(Nuntana Kasitanon)、陳得源(Der-Yuan Chen)、(Sang-Cheol Bae)、(Meng Tao Li)、(Sandra Navarra)、(Yoshiya Tanaka)、莫志超(Chi Chiu Mok)*,Executive Summary of the 2024 Asia-Pacific League of Associations for Rheumatology Consensus Statements on Lupus Nephritis Management,International Journal of Rheumatic Diseases,2025 Jan,28(1):e70022 2025 . 01
4 (Kuo-Tung Tang)、(Yu-Sin Chen)、(Tzu-Ting Chen)、(Ya-Hsuan Chao)、(Shu-Ping Kung)、陳得源(Der-Yuan Chen)*、林季千(Chi-Chien Lin)*,Inhibiting Tyrosine Kinase 2 Ameliorates Antiphospholipid Syndrome Nephropathy,MEDIATORS OF INFLAMMATION,2024 Dec,2024():568822, 2024 . 12
5 廖采苓(Tsai-Ling Liao)*、陳得源(Der-Yuan Chen)、謝世良(Shie-Liang Hsieh)、楊盈盈(Ying-Ying Yang)、陳一銘(Yi-Ming Chen)、譚國棟(Kuo-Tung Tang)、張崇信(Chung-Hsin Chang)、楊勝舜(Sheng-Shun Yang),Platelet-derived mitochondria regulate lipid metabolism in nonalcoholic steatohepatitis through extracellular vesicles,HEPATOLOGY,2024 Nov,00():000-000 2024 . 11
6 陳柏谷(Po-Ku Chen)、陳一銘(Yi-Ming Chen)、陳健尉(Jeremy J. W. Chen)、陳得源(Der-Yuan Chen)*,Anti-peptide antibodies, anti-SNRK and anti-HUWE1 antibodies as potential predictors of good response to tofacitinib therapy in rheumatoid arthritis patients,RHEUMATOLOGY,2024 Oct,00():1-10 2024 . 10
7 陳彥如(Yen-Ju Chen)、陳得源(Der-Yuan Chen)、藍顥章(Haw-Chang Lan)、黃安志(An-Chih Huang)、陳怡行(Yi-Hsing Chen)、黃文男(Wen-Nan Huang)、陳信華(Hsin-Hua Chen)*,An optimal deep learning model for the scoring of radiographic damage in patients with ankylosing spondylitis,Therapeutic Advances in Musculoskeletal Disease,2024 Sep,16():1-11 2024 . 09
8 曾博修(Bor-Show Tzang)、(Hao-Yang Chin)、(Chih-Chen Tzang)、莊佩樺(Pei-Hua Chuang)、陳得源(Der-Yuan Chen)*、徐再靜(Tsai-Ching Hsu)*,Parvovirus B19 Infection Is Associated with the Formation of Neutrophil Extracellular Traps and Thrombosis: A Possible Linkage of the VP1 Unique Region,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2024 Sep,25(18):9917 2024 . 09
9 張敬昆(Ching-Kun Chang)、李宜珍(Yi-Chen Li)、陳柏谷(Po-Ku Chen)、張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)*,Elevated remnant cholesterol as a potential predictor for cardiovascular events in rheumatoid arthritis patients,Frontiers in Cardiovascular Medicine,2024 Sep,11():1449219 2024 . 09
10 陳得源(Der-Yuan Chen)*,Reply to "Letter to the Editor": Exploring Multidimensional Factors of Herpes Zoster Risk in Rheumatoid Arthritis Patients Undergoing JAK Inhibitor Treatment,CLINICAL RHEUMATOLOGY,2024 Aug,43(9):3035 2024 . 08
11 陳柏谷(Po-Ku Chen)、張詩欣(Shih-Hsin Chang)、陳一銘(Yi-Ming Chen)、陳信華(Hsin-Hua Chen)、黃柏豪(Po-Hao Huang)、黃建中(Huang, Chien-Chung)、楊凱介(YEO KAI-JIEH)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Prior herpes zoster occurrence and high-dose corticosteroids increase herpes zoster risk in rheumatoid arthritis patients receiving janus kinase inhibitors in a retrospective and observational study,CLINICAL RHEUMATOLOGY,2024 Aug,43(8):2503-2511 2024 . 08
12 陳一銘(Yi-Ming Chen)、陳柏谷(Po-Ku Chen)、張詩欣(Shih-Hsin Chang)、陳信華(Hsin-Hua Chen)、(Jun-Peng Chen)、譚國棟(Kuo-Tung Tang)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Baseline ANA and Anti-Ro60/SSA Antibody as Potential Predictors for Immunogenicity and Poor EULAR Response in Adalimumab-Treated RA Patients,JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS,2024 Aug,2024():9 2024 . 08
13 (Yung Kai Lin)、林嘉德(Chia-Der Lin)、陳得源(Der-Yuan Chen)、林姸如(Blossom Yen-Ju Lin)*,Effects of grit on medical students’ wellbeing during clerkships: a longitudinal observational cohort study,Frontiers in Medicine,2024 May,11():1331402 2024 . 05
14 陳柏谷(PoKu Chen)、陳一銘(Yi-Ming Chen)、陳信華(Hsin-Hua Chen)、廖采苓(Tsai-Ling Liao)、張詩欣(Shih-Hsin Chang)、楊凱介(YEO KAI-JIEH)、黃柏豪(Po-Hao Huang)、陳得源(Der-Yuan Chen)*,Association of the Reduced Levels of Monocyte Chemoattractant Protein-1 with Herpes Zoster in Rheumatoid Arthritis Patients Treated with Janus Kinase Inhibitors in a Single-Center Cohort,Microorganisms,2024 May,12(5):974 2024 . 05
15 譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)、陳怡行(Yi-Hsing Chen)*,A study on irritable bowel syndrome, temporomandibular disorder, and restless leg syndrome in Chinese patients with fibromyalgia,International Journal of Rheumatic Diseases,2024 May,27(5):e15149 2024 . 05
16 陳得源(Der-Yuan Chen)、(Po-I Huang)、譚國棟(Kuo-Tung Tang)*,Characteristics of long COVID in patients with autoimmune rheumatic diseases: a systematic review and meta-analysis,Rheumatology Advances in Practice,2024 Mar,8(2):rkae027 2024 . 03
17 (Gihan Hamdy Elsisi)*、謝松洲(Song-Chou Hsieh)、陳得源(Der-Yuan Chen),The economic burden of systemic lupus erythematosus in Taiwan,JOURNAL OF MEDICAL ECONOMICS,2024 Feb,27(S1):56-66 2024 . 02
18 陳柏谷(PoKu Chen)、許偉帆(Hsu, Wei-Fan)、彭成元(Peng, Cheng-Yuan)、廖采苓(Tsai-Ling Liao)、張詩欣(Shih-Hsin Chang)、陳信華(Hsin-Hua Chen)、陳珠璜(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,Significant association of elevated serum galectin-9 levels with the development of non-alcoholic fatty liver disease in patients with rheumatoid arthritis,Frontiers in Medicine,2024 Feb,11():1347268 2024 . 02
19 何瑋立(Wei-Li Ho)、陳信華(Hsin-Hua Chen)、陳柏谷(PoKu Chen)、廖采苓(Tsai-Ling Liao)、張詩欣(Shih-Hsin Chang)、陳一銘(Yi-Ming Chen)、林敬恒(Ching-Heng Lin)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)*,Increased NAFLD risk in newly diagnosed patients with RA during the first 4 years of follow-up: a nationwide, population-based cohort study,BMJ Open,2024 Jan,14(1):e079296 2024 . 01
20 陳柏谷(PoKu Chen)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)*,The NLRP3 Inflammasome as a Pathogenic Player Showing Therapeutic Potential in Rheumatoid Arthritis and Its Comorbidities: A Narrative Review,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2024 Jan,25(1):626 2024 . 01
21 譚國棟(Kuo-Tung Tang)、簡涵如(Han-Ju Chien)、張雅涵(Ya-Han Chang)、廖采苓(Tsai-Ling Liao)、陳得源(Der-Yuan Chen)*、賴建成(Chien-Cheng Lai)*,Metabolic disturbances in systemic lupus erythematosus evaluated with UPLC-MS/MS,CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,2024 Jan,42(1):15-23 2024 . 01
22 邱瑩明(Ying-Ming Chiu)、陳得源(Der-Yuan Chen)*,Biological ageing: a promising target for prevention and management of rheumatoid arthritis,Lancet Healthy Longevity,2023 Dec,5(1):E6-E7 2023 . 12
23 (Chia-Chu Meng)、陳得源(Der-Yuan Chen)、陳怡行(Yi-Hsing Chen)、黃文男(Wen-Nan Huang)、陳信華(Hsin-Hua Chen)*,Antirheumatic drugs and the risk of nonalcoholic fatty liver disease in patients with rheumatoid arthritis: A nationwide, population-based cohort study,International Journal of Rheumatic Diseases,2023 Dec,00():1-13 2023 . 12
24 陳家慶(Chen, Chia-Ching)、陳得源(Der-Yuan Chen)*,The Clinical Utility of Musculoskeletal Ultrasound for Disease Activity Evaluation and Therapeutic Response Prediction in Rheumatoid Arthritis Patients: A Narrative Review,Journal of Medical Ultrasound,2023 Nov,31(4):275-281 2023 . 11
25 廖采苓(Tsai-Ling Liao)*、劉宏仁(Hung-Jen Liu)、陳得源(Der-Yuan Chen)、譚國棟(Kuo-Tung Tang)、陳一銘(Yi-Ming Chen)、劉伯瑜(Po-Yu Liu)*,SARS-CoV-2 primed platelets-derived microRNAs enhance NETs formation by extracellular vesicle transmission and TLR7/8 activation,Cell Communication and Signaling,2023 Oct,21(1):304 2023 . 10
26 鄭文建(Wen-Chien Cheng)、張詩欣(Shih-Hsin Chang)*、陳偉峻(Wei-Chun chen)、吳秉儒(Bing-Ru Wu)、陳家弘(Chia-Hung Chen)、林季千(Chi-Chien Lin)、徐武輝(Wu-Huei Hsu)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Application of impulse oscillometry to detect interstitial lung disease and airway disease in adults with rheumatoid arthritis,BMC Pulmonary Medicine,2023 Sep,23(2023):331 2023 . 09
27 藍忠亮(Joung-Liang Lan)、張詩欣(Shih-Hsin Chang)、蔡嘉哲(Gregory J. Tsay)、陳得源(Der-Yuan Chen)、趙玉華(Yu-Hua Chao)、李如璧(Ju-Pi Li)*,Immune cell profiles of idiopathic inflammatory myopathy patients expressed anti-aminoacyl tRNA synthetase or anti-melanoma differentiation-associated gene 5 autoantibodies,BMC IMMUNOLOGY,2023 Sep,24(1):33 2023 . 09
28 林靖才(Ching-Tsai Lin)、黃文男(Wen-Nan Huang)、(Jun-Peng Chen)、洪維廷(Wei-Ting Hung)、謝祖怡(Tsu-Yi Hsieh)、陳信華(Hsin-Hua Chen)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)、陳怡行(Yi-Hsing Chen)、陳一銘(Yi-Ming Chen)*,Association of Hydroxychloroquine Use with a Dose- Dependent Decrease in Mortality Risk in Patients with Elderly-Onset Rheumatoid Arthritis,Rheumatology and Therapy,2023 Aug,():1-14 2023 . 08
29 黃章倫(Chang-Lun Huang)、陳得源(Der-Yuan Chen)、(Chih-Chen Tzang)、(Jhen-Wei Lin)、曾博修(Bor-Show Tzang)、徐再靜(Tsai-Ching Hsu)*,Celastrol attenuates human parvovirus B19 NS1‑induced NLRP3 inflammasome activation in macrophages,Molecular Medicine Reports,2023 Aug,28(4):193 2023 . 08
30 林昀嫻(Yun-Hsien Lin)、張詩欣(Shih-Hsin Chang)、許登傑(Teng-Chieh Hsu)、陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Elevated monocyte distribution width in patients with active adult-onset Still’s disease: a novel activity indicator,CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,2023 Jul,(): 2023 . 07
31 許登傑(Teng-Chieh Hsu)、張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)*,Change in immunoglobulin A level in ankylosing spondylitis patients treated with different biologic DMARDs: a retrospective study in a medical center in Taiwan,中華民國風濕病雜誌,2023 Jul,2023(37):33-41 2023 . 07
32 譚國棟(Kuo-Tung Tang)、廖采苓(Tsai-Ling Liao)、陳怡行(Yi-Hsing Chen)、陳得源(Der-Yuan Chen)、賴國隆(Kou-Lung Lai)*,Subcutaneous Tocilizumab May Be Effective in Refractory Fibromyalgia Patients,Biomedicines,2023 Jun,11(7):1174 2023 . 06
33 張敬昆、蔣恩沛(En-Pei Isabel Chiang)、張光喜(Kuang-Hsi Chang)、譚國棟(Kuo-Tung Tang)、陳柏谷(PoKu Chen)、葉晞彤(YIP HEI-TUNG)、(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,The Sizes and Composition of HDL-Cholesterol Are Significantly Associated with Inflammation in Rheumatoid Arthritis Patients,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2023 Jun,24(13):10645 2023 . 06
34 (Simon Kraler)、(Florian A. Wenzl)、(Jody Vykoukal)、(Johannes F. Fahrmann)、沈明毅(Ming-Yi Shen)、陳得源(Der-Yuan Chen)、張坤正(Kuan-Cheng Chang)、張敬昆、(Arnold von Eckardstein)、(Lorenz Raber)、(Francois Mach)、(David Nanchen)、(Christian M. Matter)、(Luca Liberale)、(Giovanni G. Camici)、(Alexander Akhmedov)*、陳珠璜(Chu-Huang Chen)*、(Thomas F. Luscher)*,Low-density lipoprotein electronegativity and risk of death after acute coronary syndromes: A case-cohort analysis,ATHEROSCLEROSIS,2023 May,376(2023):43-52 2023 . 05
35 廖采苓(Tsai-Ling Liao)、陳一銘(Yi-Ming Chen)、譚國棟(Kuo-Tung Tang)、楊盈盈(Ying-Ying Yang)、陳得源(Der-Yuan Chen)、(Tsung-Hsien Chan)、(Hui-Ju Tsai)、謝世良(Shie-Liang Hsieh)*,CLEC18A Impairs Phagocytosis by Reducing FcγRIIA Expression and Arresting Autophagosome-Lysosome Fusion,Microbiology Spectrum,2023 May,():e0290322 2023 . 05
36 張敬昆、張光喜(Kuang-Hsi Chang)、鄭維中(Cheng, Wei-Chung)、陳柏谷(PoKu Chen)、蔣恩沛(En-Pei Isabel Chiang)、張詩欣(Shih-Hsin Chang)、(Yi-Chen Li)、陳珠璜(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,Lipid metabolomic signature might predict subclinical atherosclerosis in patients with active rheumatoid arthritis,CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,2023 May,41(5):1120-1128 2023 . 05
37 曾浩翔(CHEN HAO XIANG)、張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)、藍忠亮(Joung-Liang Lan)、楊凱介(Yeo Kai Jieh)、黃柏豪(Po-Hao Huang)、黃春明(Chung-Ming Huang)、黃志平(Chi-Ping Huang)、鄒頡龍(Chieh-Lung Chou)*、吳柏樟(Wu, Po-Chang)*,Mirabegron is better tolerated than solifenacin in Sjogren's syndrome patients with overactive bladder symptoms—A randomized controlled trial,LUTS-Lower Urinary Tract Symptoms,2023 Apr,10(1111): 2023 . 04
38 陳柏谷(PoKu Chen)、楊凱介(Yeo Kai Jieh)、張詩欣(Shih-Hsin Chang)、廖采苓(Tsai-Ling Liao)、周家卉(Chia-Hui Chou)、藍忠亮(Joung-Liang Lan)、張敬昆、陳得源(Der-Yuan Chen)*,The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity,Virology Journal,2023 Feb,20(33): 2023 . 02
39 陳柏谷(PoKu Chen)、廖采苓(Tsai-Ling Liao)、張詩欣(Shih-Hsin Chang)、楊凱介(Yeo Kai Jieh)、周家卉(Chia-Hui Chou)、陳得源(Der-Yuan Chen)*,High-titer anti-interferon-g neutralizing autoantibodies linked to opportunistic infections in patients with adult-onset still’s disease,Frontiers in Medicine,2023 Jan,9():1097514 2023 . 01
40 陳得源(Der-Yuan Chen)、陳信華(Hsin-Hua Chen)、張詩欣(Shih-Hsin Chang)、陳一銘(Yi-Ming Chen)、黃柏豪(Po-Hao Huang)、謝佳偉(Chia-Wei Hsieh)、藍忠亮(Joung-Liang Lan)、譚國棟(Kuo-Tung Tang)*,The Impact of b/tsDMARD Dose Reduction on Chronic Hepatitis B in Rheumatoid Arthritis Patients: A Two-Center Long-Term Safety Analysis,Journal of Clinical Medicine,2023 Jan,12(1):86 2023 . 01
41 張詩欣(Shih-Hsin Chang)、許登傑(Teng-Chieh Hsu)、黃柏豪(Po-Hao Huang)、黃建中(Huang, Chien-Chung)、楊凱介(Yeo Kai Jieh)、洪偉哲(Wei-Jhe Hong)、陳柏谷(PoKu Chen)、林昀嫻(Yun-Hsien Lin)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,A Streamlined Diagnostic Process Improved the Outcomes of Patients with Adult-Onset Still’s Disease: A Single-Center Retrospective Observational Study,Rheumatology and Therapy,2022 Dec,(2022): 2022 . 12
42 譚國棟(Kuo-Tung Tang)、林靖淳(Ching-Chun Lin)、陳怡行(Yi-Hsing Chen)、廖采苓(Tsai-Ling Liao)、陳得源(Der-Yuan Chen)、楊勝舜(Sheng-Shun Yang)、陳家昌(Chia-Chang Chen)*,Direct‐Acting Antiviral Drugs Reduce Fibromyalgia Symptoms in Patients with Chronic Hepatitis C,Journal of Clinical Medicine,2022 Sep,11(18):5327 2022 . 09
43 張凱發(TEO KAI FA)、陳得源(Der-Yuan Chen)、徐婕婷(Jeh-Ting Hsu)、賴怡樺(LAI YI-HUA)、張敬昆、薛博仁(Hsueh, Po-Ren)、藍忠亮(Joung-Liang Lan)*、徐婕琳(Hsu, Jye-Lin)*,Screening and characterization of myositis-related autoantibodies in COVID-19 patients,CTS-Clinical and Translational Science,2022 Sep,00():1-11 2022 . 09
44 (Kooi-Heng Ng)、陳得源(Der-Yuan Chen)、林敬恒(Ching-Heng Lin)、趙文震(Wen-Cheng Chao)、陳信華(Hsin-Hua Chen)*,Analysis of risk factors of mortality in rheumatoid arthritis patients with interstitial lung disease: a nationwide, population-based cohort study in Taiwan,RMD Open,2022 Jul,8(2):e002343 2022 . 07
45 陳柏谷(PoKu Chen)、魏秀娟(Shiow-Jiuan Wey)、陳得源(Der-Yuan Chen)*,Interleukin-18: a biomarker with therapeutic potential in adult-onset Still's disease,Expert Review of Clinical Immunology,2022 Jul,():1-11 2022 . 07
46 (Yi-Ming Chen)、(I-Chieh Chen)、(Ya-Hsuan Chao)、(Hsin-Hua Chen)、陳柏谷(PoKu Chen)、張詩欣(Shih-Hsin Chang)、楊凱介(Yeo Kai Jieh)、(Shiow-Jiuan Wey)、林季千(Chi-Chien Lin)*、陳得源(Der-Yuan Chen)*,Dextromethorphan Exhibits Anti-Inflammatory and Immunomodulatory Effects in a Murine Model: Therapeutic Implication in Psoriasis,Life-Basel,2022 May,12(5):696 2022 . 05
47 譚國棟(Kuo-Tung Tang)、許伯爵(Bo-Chueh Hsu)、陳得源(Der-Yuan Chen)*,Immunogenicity, Effectiveness, and Safety of COVID-19 Vaccines in Rheumatic Patients: An Updated Systematic Review and Meta-Analysis,Biomedicines,2022 Apr,10(4):834 2022 . 04
48 田霓(Ni Tien)、張煜昌(Yu-Chang Chang)、陳柏谷(PoKu Chen)、林惠茹(Hui-Ju Lin)、張詩欣(Shih-Hsin Chang)、藍忠亮(Joung-Liang Lan)、薛博仁(Hsueh, Po-Ren)、張敬昆、陳得源(Der-Yuan Chen)*,The Immunogenicity and Safety of Three Types of SARS-CoV-2 Vaccines in Adult Patients with Immune-Mediated Inflammatory Diseases: A Longitudinal Cohort Study,Biomedicines,2022 Apr,10(4):911 2022 . 04
49 黃祿崴(Lu-Wei Huang)、魏正宗(Wei,Cheng-Chung)、陳得源(Der-Yuan Chen)、陳彥如(Yen-Ju Chen)、譚國棟(Kuo-Tung Tang)、柯泰名(Tai-Ming Ko)、陳信華(Hsin-Hua Chen)*,Bidirectional association between systemic lupus erythematosus and macrophage activation syndrome: a nationwide population-based study,RHEUMATOLOGY,2022 Mar,61(3):1123-1132 2022 . 03
50 詹毓哲(Yu-Tse Tsan)、陳得源(Der-Yuan Chen)、劉伯瑜(Po-Yu Liu)、(Endah Kristiani)、(Kieu Lan Phuong Nguyen)、楊朝棟(Chao-Tung Yang)*,The Prediction of Influenza-like Illness and Respiratory Disease Using LSTM and ARIMA,International Journal of Environmental Research and Public Health,2022 Feb,19(3):1858 2022 . 02
51 陳得源(Der-Yuan Chen)、林敬恒(Ching-Heng Lin)、陳信華(Hsin-Hua Chen)、譚國棟(Kuo-Tung Tang)*,Association of tumor necrosis factor-α inhibitors and liver cirrhosis in patients with rheumatoid arthritis: A nationwide population-based nested case-control study,International Journal of Rheumatic Diseases,2021 Dec,00():1-8 2021 . 12
52 余光輝(Yu, Kuang-Hui)、陳信華(Chen, Hsin-Hua)、鄭添財(Cheng, Tien-Tsai)、詹永嬌(Jan, Yeong-Jian)、翁孟玉(Weng, Meng-Yu)、林永章(Lin, Yeong-Jang)、陳宏安(Chen, Hung-An)、曾瑞成(Cheng, Jui-Tseng)、黃光永(Huang, Kuang-Yung)、李克仁(Li, Ko-Jen)、蘇昱日(Su, Yu-Jih)、梁培英(Leong, Pui-Ying)、蔡文展(Tsai, Wen-Chan)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Consensus recommendations on managing the selected comorbidities including cardiovascular disease, osteoporosis, and interstitial lung disease in rheumatoid arthritis,MEDICINE,2021 Dec,101(1):e28501 2021 . 12
53 黃柏豪(Po-Hao Huang)、陳得源(Der-Yuan Chen)*,【Educational Forum】Diagnostic Value of the Salivary Gland Ultrasonography Scoring System in Patients with Primary Sjogren’s Syndrome,Journal of Medical Ultrasound,2021 Dec,19(4):235-236 2021 . 12
54 廖采苓(Tsai-Ling Liao)*、陳一銘(Yi-Ming Chen)、謝世良(Shie-Liang Hsieh)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)、楊盈盈(Ying-Ying Yang)、劉宏仁(Hung-Jen Liu)、楊勝舜(Sheng-Shun Yang),Hepatitis C Virus-Induced Exosomal MicroRNAs and Toll-Like Receptor 7 Polymorphism Regulate B-Cell Activating Factor,mBio,2021 Nov,12(6):e02764-21 2021 . 11
55 張敬昆、鄭維中(Cheng, Wei-Chung)、馬文隆(Wen-Lung Ma)、陳柏谷(PoKu Chen)、(Chu-Huang Chen)、沈培鈞(Pei-Chun Shen)、(Chia-Ching Chen)、張詩欣(Shih-Hsin Chang)、賴怡樺(LAI YI-HUA)、陳得源(Der-Yuan Chen)*,The Potential Role of Electronegative High-Density Lipoprotein H5 Subfraction in RA-Related Atherosclerosis,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2021 Oct,22(21):11419 2021 . 10
56 陳柏谷(PoKu Chen)、楊凱介(Yeo Kai Jieh)、黃柏豪(Po-Hao Huang)、張詩欣(Shih-Hsin Chang)、張敬昆、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Increased Lipid Peroxidation May Be Linked to Ferritin Levels Elevation in Adult-Onset Still’s Disease,Biomedicines,2021 Oct,9(11):1508 2021 . 10
57 陳得源(Der-Yuan Chen)、黃彥翔(Yen-Hsiang Huang)、陳一銘(Yi-Ming Chen)、陳健尉(Jeremy J W Chen)、楊宗穎(Tsung-Ying Yang)、張基晟(Gee-Chen Chang)、譚國棟(Kuo-Tung Tang)*,ANA positivity and complement level in pleural fluid are potential diagnostic markers in discriminating lupus pleuritis from pleural effusion of other aetiologies,Lupus Science & Medicine,2021 Oct,8(1):e000562 2021 . 10
58 林雍凱(Yung Kai Lin)、林妍如(Blossom Yen-Ju Lin)*、林嘉德(Chia-Der Lin)、陳得源(Der-Yuan Chen),Relationship between medical students’ negative perceptions of colleagues’ work–life and burn-out during clerkships: a longitudinal observational cohort study,BMJ Open,2021 Sep,11(): 2021 . 09
59 楊晶安(Yang, Chin-An)、陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、張敬昆、張建國(Jan-Gowth Chang)、張詩欣(Shih-Hsin Chang)、林季千(Chi-Chien Lin)、陳得源(Der-Yuan Chen)*,Expression signature of inflammation-associated long non-coding RNAs in adult-onset Still’s disease,CLINICAL AND EXPERIMENTAL RHEUMATOLOGY,2021 Sep,39Suppl132(5):67-74 2021 . 09
60 譚國棟(Kuo?Tung Tang)、謝佳偉(Chia?Wei Hsieh)、陳信華(Hsin?Hua Chen)、陳一銘(Yi?Ming Chen)、張詩欣(Shih-Hsin Chang)、黃柏豪(Po-Hao Huang)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,The effectiveness of tocilizumab in treating refractory adult-onset Still's disease with dichotomous phenotypes: IL-18 is a potential predictor of therapeutic response,CLINICAL RHEUMATOLOGY,2021 Sep,2021(): 2021 . 09
61 廖采苓(Tsai-Ling Liao)、陳一銘(Yi-Ming Chen)、譚國棟(Kuo-Tung Tang)、陳柏谷(PoKu Chen)、劉宏仁(Hung-Jen Liu)、陳得源(Der-Yuan Chen)*,MicroRNA-223 inhibits neutrophil extracellular traps formation through regulating calcium influx and small extracellular vesicles transmission,Scientific Reports,2021 Aug,11(1): 2021 . 08
62 張敬昆、陳柏谷(PoKu Chen)、(Chia-Ching Chen)、張詩欣(Shih-Hsin Chang)、(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,Increased Levels of Omega-3 Fatty Acids and DHA Are Linked to Pain Reduction in Rheumatoid Arthritis Patients Treated with Janus Kinase Inhibitors,Nutrients,2021 Aug,13(9):3050 2021 . 08
63 陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、黃柏豪(Po-Hao Huang)、徐婕琳(Hsu, Jye-Lin)、張敬昆、田霓(Ni Tien)、林惠茹(Hui-Ju Lin)、陳得源(Der-Yuan Chen)*,Interleukin-18 Is a Potential Biomarker to Discriminate Active Adult-Onset Still’s Disease From COVID-19,Frontiers in Immunology,2021 Jul,12(): 2021 . 07
64 陳信華(Hsin-Hua Chen)、陳享民(Hsian-Min Chen)、林敬恒(Ching-Heng Lin)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)、魏正宗(Wei,Cheng-Chung)、趙文震(Wen-Cheng Chao)*,Association of the Risk of Primary Sjögren's Syndrome With Fibrocystic Breast Disease: A Nationwide, Population-Based Study,Frontiers in Medicine,2021 Jul,8(): 2021 . 07
65 陳柏谷(PoKu Chen)、陳得源(Der-Yuan Chen)*,An Update on the Pathogenic Role of Macrophages in Adult-Onset Still’s Disease and Its Implication in Clinical Manifestations and Novel Therapeutics,Journal of Immunology Research,2021 Jun,2021(): 2021 . 06
66 (Wei-Ting Hung)、洪舜郁(Shuen-Iu Hung)、陳一銘(Yi-Ming Chen)、謝佳偉(Chia-Wei Hsieh)、陳信華(Hsin-Hua Chen)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)*、藍祚鴻(Tsuo-Hung Lan)*,The Association of ATG16L1 Variations with Clinical Phenotypes of Adult-Onset Still’s Disease,Genes,2021 Jun,12(6):904 2021 . 06
67 (Yi-Sheng Yang)、劉珮瑾(Pei-Chin Liu)、林雍凱(Yung Kai Lin)、林嘉德(Chia-Der Lin)、陳得源(Der-Yuan Chen)、林姸如(Blossom Yen-Ju Lin)*,Medical students' preclinical service-learning experience and its effects on empathy in clinical training,BMC Medical Education,2021 May,21(1):301 2021 . 05
68 (Ying--Ming Chiu)*、(Yi--Peng Lu)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)、(Jung--Der Wang),Lifetime Risks, Life Expectancy, and Health Care Expenditures for Rheumatoid Arthritis: A Nationwide Cohort Followed Up From 2003 to 2016,Arthritis & Rheumatology,2021 May,73(5):750-758 2021 . 05
69 陳得源(Der-Yuan Chen)、(Tatsuya Sawamura)、(Richard A. F. Dixon)、(Jose Luis Sanchez-Quesada)、(Chu-Huang Chen)*,Autoimmune Rheumatic Diseases: An Update on the Role of Atherogenic Electronegative LDL and Potential Therapeutic Strategies,Journal of Clinical Medicine,2021 May,10(9):1992 2021 . 05
70 洪維廷(Wei-Ting Hung)、陳一銘(Yi-Ming Chen)、洪舜郁(Shuen-Iu Hung)、陳信華(Hsin-Hua Chen)、龔寗容、謝佳偉(Chia-Wei Hsieh)、譚國棟(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)*,CARD8 SNP rs11672725 Identified as a Potential Genetic Variant for Adult-Onset Still’s Disease,Life-Basel,2021 Apr,11(5):382 2021 . 04
71 (Chi Chiu Mok)*、(Laniyati Hamijoyo)、(Nuntana Kasitanon)、陳得源(Der-Yuan Chen)、(Sheng Chen)、(Kunihiro Yamaoka)、(Kenji Oku)、(Meng Tao Li)、(Leonid Zamora)、(Sang-Cheol Bae)、(Sandra Navarra)、(Eric F Morand)、(Yoshiya Tanaka),The Asia-Pacific League of Associations for Rheumatology consensus statements on the management of systemic lupus erythematosus,Lancet Rheumatology,2021 Mar,3(7):e517-e531 2021 . 03
72 譚國棟(Kuo-Tung Tang)、徐伯爵(Bo-Chueh Hsu)、陳得源(Der-Yuan Chen)*,Autoimmune and Rheumatic Manifestations Associated With COVID-19 in Adults: An Updated Systematic Review,Frontiers in Immunology,2021 Mar,12():645013 2021 . 03
73 陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、陳一銘(Yi-Ming Chen)、陳信華(Hsin-Hua Chen)、張詩欣(Shih-Hsin Chang)、鍾加明(Chia-Min Chung)、(Nurul H. Rutt)、(Ti-Myen Tan)、(Raja Nurashirin Raja Mamat)、(Nur Diana Anuar)、(Jonathan M. Blackburn)、陳得源(Der-Yuan Chen)*,Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA,Journal of Immunology Research,2021 Mar,2021(): 2021 . 03
74 陳信華(Hsin-Hua Chen)、林敬恒(Ching-Heng Lin)、謝祖怡(Tsu-Yi Hsieh)、陳得源(Der-Yuan Chen)、英家慶(Jia-Ching Ying)、趙文震(Wen-Cheng Chao)*,Factors Associated with Incident Severe Pulmonary Arterial Hypertension in Systemic Autoimmune Rheumatic Diseases: a Nationwide Study,RHEUMATOLOGY,2021 Feb,60(11):5351-5361 2021 . 02
75 蘇雅麗(Nga-Lai Sou)、(Yu-Hsuan Huang)、陳得源(Der-Yuan Chen)、陳一銘(Yi-Ming Chen)、唐烽堯、(Hsin-An Ko)、(Yi-Hsuan Fan)、林宜瑩(Yi-Ying Lin)、(Yi-Cheng Wang)、(Hui-Ming Chih)、(Barry Shane)、黃文男(Wen-Nan Huang)、蔣恩沛(En-Pei Isabel Chiang)*,Folinate Supplementation Ameliorates Methotrexate Induced Mitochondrial Formate Depletion In Vitro and In Vivo,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2021 Jan,22(3):1350 2021 . 01
76 陳一銘(Yi-Ming Chen)、陳柏谷(PoKu Chen)、張敬昆、林季千(Chi-Chien Lin)、陳信華(Hsin-Hua Chen)、藍忠亮(Joung-Liang Lan)、張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)*,Association of Apolipoprotein E Polymorphism with Adipokines and Cardiovascular Disease Risk in Rheumatoid Arthritis Patients,Life-Basel,2020 Dec,10(12):330 2020 . 12
77 陳信華(Hsin-Hua Chen)、雍有明(You-Ming Yong)、(Ching-Heng Lin)、陳怡行(Yi-Hsing Chen)、陳得源(Der-Yuan Chen)、英家慶(Jia-Ching Ying)、趙文震(Wen-Cheng Chao)*,Air pollutants and development of interstitial lung disease in patients with connective tissue disease: a population-based case-control study in Taiwan,BMJ Open,2020 Dec,10(12):e041405 2020 . 12
78 陳彥如(Yen-Ju Chen)、陳一銘(Yi-Ming Chen)、黃文男(Wen-Nan Huang)、陳信華(Hsin-Hua Chen)、廖采苓(Tsai-Ling Liao)、(Jun-Peng Chen)、謝祖怡(Tsu-Yi Hsieh)、陳怡行(Yi-Hsing Chen)、陳得源(Der-Yuan Chen)*,Herpes Zoster in rheumatoid arthritis patients receiving tofacitinib, a single center experience from Taiwan,MEDICINE,2020 Oct,99(41):e22504 2020 . 10
79 張敬昆、陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、張詩欣(Shih-Hsin Chang)、‪謝祖怡(Tsu-Yi Hsieh)、廖佩娟(LIAO PEI-JYUAN)、陳珠璜(Chu-Huang Chen)、陳得源(Der-Yuan Chen)*,Association of Electronegative LDL with Macrophage Foam Cell Formation and CD11c Expression in Rheumatoid Arthritis Patients,INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2020 Aug,21(16):E5883 2020 . 08
80 (Kooi-Heng Ng)、陳得源(Der-Yuan Chen)、(Ching-Heng Lin)、(Wen-Cheng Chao)、陳一銘(Yi-Ming Chen)、陳怡行(Yi-Hsing Chen)、黃文男(Wen-Nan Huang)、謝祖怡(Tsu-Yi Hsieh)、賴國隆(Kuo-Lung Lai)、譚國棟(Kuo-Tung Tang)、陳信華(Hsin-Hua Chen)*,Risk of interstitial lung disease in patients with newly diagnosed systemic autoimmune rheumatic disease: A nationwide, population-based cohort study,SEMINARS IN ARTHRITIS AND RHEUMATISM,2020 Jul,50(5):840-845 2020 . 07
81 陳柏谷(PoKu Chen)、謝世良(Shie-Liang Hsieh)、藍忠亮(Joung-Liang Lan)、林季千(Chi-Chien Lin)、張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)*,Elevated Expression of C-Type Lectin Domain Family 5-Member A (CLEC5A) and Its Relation to Inflammatory Parameters and Disease Course in Adult-Onset Still's Disease.,Journal of Immunology Research,2020 Apr,2020():1-11 2020 . 04
82 (Ee-Ling Lai)、黃文男(Wen-Nan Huang)、陳信華(Hsin-Hua Chen)、(Jun-Peng Chen)、陳得源(Der-Yuan Chen)、謝祖怡(Tsu-Yi Hsieh)、洪維廷(Wei-Ting Hung)、賴國隆(Kuo-Lung Lai)、林靖才(Ching-Tsai Lin)、譚國棟(Kuo-Tung Tang)、陳一銘(Yi-Ming Chen)*、陳怡行(Yi-Hsing Chen)*,Degraded microarchitecture by low trabecular bone score is associated with prevalent vertebral fractures in patients with systemic lupus erythematosus,Archives of Osteoporosis,2020 Mar,15(1):54 2020 . 03
83 邱瑩明、陳得源(Der-Yuan Chen)*,Infection risk in patients undergoing treatment for inflammatory arthritides: non-biologics versus biologics,Expert Review of Clinical Immunology,2020 Feb,16(2):207-228 2020 . 02
84 楊凱介(Yeo Kai Jieh)、陳信華(Hsin-Hua Chen)、陳一銘(Yi-Ming Chen)、林敬恆(Ching-Heng Lin)、陳得源(Der-Yuan Chen)、(Chih-Ming Lai)、(Wen-Cheng Chao)*,Hydroxychloroquine may reduce risk of Pneumocystis pneumonia in lupus patients: a Nationwide, population-based casecontrol study,BMC INFECTIOUS DISEASES,2020 Feb,20(1):1-8 2020 . 02
85 陳信華(Hsin Hua Chen)*、陳得源(Der-Yuan Chen)、黃良吉(Liang Gie Huang)、陳一銘(Yi-Ming Chen)、謝佳偉(Chia Wei Hsieh)、洪維廷(Wei Ting Hung)、譚國棟(Kuo Tung Tang)、陳錦(Gin Chen),Association between Periodontitis and the Risk of Inadequate Disease Control in Patients with Rheumatoid Arthritis Under Biological Treatment,JOURNAL OF CLINICAL PERIODONTOLOGY,2020 Feb,47(2):148-159 2020 . 02
86 陳一銘(Yi-Ming Chen)、洪維廷(Wei-Ting Hung)、(Wan-Chun Chang)、謝佳偉(Chia-Wei Hsieh)、鐘文宏(Wen-Hung Chung)、藍忠亮(Joung-Liang Lan)、龔寗容、(Yun-Shien Lee)、陳得源(Der-Yuan Chen)*、洪舜郁(Shuen-Iu Hung)*,Genetic Association and Expression Correlation between Colony-Stimulating Factor 1 Gene Encoding M-CSF and Adult-Onset Still’s Disease,Journal of Immunology Research,2020 Feb,2020():1-11 2020 . 02
87 陳柏谷(PoKu Chen)、藍忠亮(Joung-Liang Lan)、李如璧(Ju-Pi Li)、張敬昆、張詩欣(Shih-Hsin Chang)、黃柏豪(Po-Hao Huang)、楊凱介(Yeo Kai Jieh)、陳得源(Der-Yuan Chen)*,Elevated plasma galectin-3 levels and their correlation with disease activity in adult-onset Still’s disease,CLINICAL RHEUMATOLOGY,2020 Jan,():1-8 2020 . 01
88 林雍凱(Yung Kai Lin)、林?如(Blossom Yen-Ju Lin)*、陳得源(Der-Yuan Chen),Do teaching strategies matter? Relationships between various teaching strategies and medical students’ wellbeing during clinical workplace training,MEDICAL TEACHER,2020 Jan,42(1):39-45 2020 . 01
89 陳得源(Der-Yuan Chen)、陳一銘(Yi-Ming Chen)、(Chin-Fu Lin)、駱哲民、劉宏仁(Hung-Jen Liu)、廖采苓(Tsai-Ling Liao)*,MicroRNA-889 Inhibits Autophagy To Maintain Mycobacterial Survival in Patients with Latent Tuberculosis Infection by Targeting TWEAK,mBio,2020 Jan,11(1):1-17 2020 . 01
90 李盈萱(Ying-Hsuan Li)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)、吳柏樟(Po-Chang Wu)*,Clinical characteristics of rheumatic patients with anti-Ku antibodies: A retrospective study in a medical center in Taiwan,中華民國風濕病雜誌,2019 Dec,33(2):56-64 2019 . 12
91 林雍凱(Yung Kai Lin)、林嘉德(Chia-Der Lin)、林姸如(Blossom Yen-Ju Lin)*、陳得源(Der-Yuan Chen),Medical students' resilience: a protective role on stress and quality of life in clerkship,BMC Medical Education,2019 Dec,19(1):1-9 2019 . 12
92 石硯如(Yen-ju Shih)*、邱瑩明、陳得源(Der-Yuan Chen),The emergence of eosinophilia in patients with rheumatoid arthritis receiving therapy with biological agents or JAK inhibitor 類風濕關節炎患者接受生物製劑及口服小分子標靶藥物後產生 之嗜酸性球增多症,中華民國風濕病雜誌,2019 Nov,33(2):48-55 2019 . 11
93 石硯如(Yen-ju Shih)*、張詩欣(Shih-Hsin Chang)、黃柏豪(Po-Hao Huang)、陳得源(Der-Yuan Chen),狼瘡性腎炎末期腎病變患者之尿毒性動脈鈣化病變,中華民國風濕病雜誌,2019 Nov,33(2):68-68 2019 . 11
94 江信毅(Hsin-I Chiang)、李建融(Jian-Rong Li)、劉俊吉(Chun-Chi Liu)、劉伯瑜(Po-Yu Liu)、陳信華(Hsin-Hua Chen)、陳一銘(Yi-Ming Chen)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,An Association of Gut Microbiota with Different Phenotypes in Chinese Patients with Rheumatoid Arthritis,Journal of Clinical Medicine,2019 Oct,8(11):1770-1788 2019 . 10
95 陳得源(Der-Yuan Chen)、(Fun Yu)、(Li-Wen Tuan)、湯澡薰(Chao-Hsiun Tang)*,Comparison of Healthcare Utilization and Costs Between RA Patients Receiving Biological and Conventional Synthetic DMARDs: A Nationwide Population-Based Cohort Study in Taiwan,Frontiers in Pharmacology,2019 Oct,10():1214-1221 2019 . 10
96 陳信華(Hsin-Hua Chen)、林敬恒(Ching-Heng Lin)、陳得源(Der-Yuan Chen)、趙文震(Wen-Cheng Chao)、陳怡行(Yi-Hsing Chen)、洪維廷(Wei-Ting Hung)、周吟怡(Yin-Yi Chou)、吳沂達(Yi-Da Wu)、陳建志(Chien-Chih Chen)*,Risk of major autoimmune diseases in female breast cancer patients: A nationwide, population-based cohort study,PLoS One,2019 Sep,14(9):e0222860 2019 . 09
97 譚國棟(Kuo-Tung Tang)、莊秉潔(Ben-Jei Tsuang)、(Kai-Chen Ku)、(Yi-Hsing Chen)、林敬恒(Ching-Heng Lin)*、陳得源(Der-Yuan Chen)*,Letter: Relationship between exposure to air pollutants and development of systemic autoimmune rheumatic diseases: a nationwide population-based case-control study,ANNALS OF THE RHEUMATIC DISEASES,2019 Sep,78(9):1288-1291 2019 . 09
98 洪偉哲(Wei-Jhe Hong)、(W. Chen)、楊凱介(Yeo Kai Jieh)、(P.-H. Huang)、陳得源(Der-Yuan Chen)*、藍忠亮(Joung-Liang Lan),Increased risk of osteoporotic vertebral fracture in rheumatoid arthritis patients with new-onset cardiovascular diseases: a retrospective nationwide cohort study in Taiwan.,OSTEOPOROSIS INTERNATIONAL,2019 Aug,30(8):1617-1625 2019 . 08
99 湯澡薰(Chao?Hsiun Tang)、(Fun Yu)、(Ching?Ya Huang)、陳得源(Der-Yuan Chen)*,Potential benefits of biologics on stroke and mortality in patients with rheumatoid arthritis: a nationwide population-based cohort study in Taiwan.,International Journal of Rheumatic Diseases,2019 Aug,22(8):1544-1552 2019 . 08
100 (E-L Lai)、黃文男(W-N Huang)、(H-H Chen)、(C-Y Hsu)、陳得源(Der-Yuan Chen)、(T-Y Hsieh)、(W-T Hung)、(C-T Lin)、賴國隆(K-L Lai)、譚國棟(K-T Tang)、陳一銘(Y-M Chen)*、陳怡行(Y-H Chen),Ten-year fracture risk by FRAX and osteoporotic fractures in patients with systemic autoimmune diseases.,LUPUS,2019 Jul,28(8):945-953 2019 . 07
101 陳一銘(Yi?Ming Chen)、(Hsin?Hua Chen)、黃文男(Wen?Nan Huang)、陳怡行(Yi?Hsing Chen)、(Tsu?Yi Hsieh)、楊勝舜(Sheng?Shun Yang)、藍忠亮(Joung-Liang Lan)*、陳得源(Der-Yuan Chen)*,Reactivation of hepatitis B virus infection following rituximab treatment in HBsAg-negative, HBcAb-positive rheumatoid arthritis patients: a long-term, real-world observation.,International Journal of Rheumatic Diseases,2019 Jun,22(6):1145-1151 2019 . 06
102 (Chuang CH)、(Cheng YC)、(Lin SC)、(Lehman CW)、(Wang SP)、陳得源(Der-Yuan Chen)、(Tsai SW)、林季千(Chi-Chien Lin)*,Atractylodin Suppresses Dendritic Cell Maturation and Ameliorates Collagen-Induced Arthritis in a Mouse Model.,JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2019 Jun,67(24):6773-6784 2019 . 06
103 (Shyh-Ren Chiang)、(Chia-Yun Lin)、陳得源(Der-Yuan Chen)、(Hui-Fang Tsai)、(Xin-Ci Lin)、(Tsai-Ching Hsu)、(Bor-Show Tzang)*,The effects of human parvovirus VP1 unique region in a mouse model of allergic asthma,PLoS One,2019 May,14(5):1-20 2019 . 05
104 陳得源(Der-Yuan Chen)、許秉寧(Ping-Ning Hsu)*、湯澡薰(Chao-Hsiun Tang)、(Lindsay Claxton)、(Satish Valluri)、(Robert A. Gerber),Tofacitinib in the treatment of moderate-to-severe rheumatoid arthritis: a cost-effectiveness analysis compared with adalimumab in Taiwan,JOURNAL OF MEDICAL ECONOMICS,2019 May,22(8):777-787 2019 . 05
105 (Yi-Ming Chen)、(, Ching-Heng Lin)、(Hsin-Hua Chen)、(Wen-Cheng Chao)、陳得源(Der-Yuan Chen)、(Che-Chen Lin)、(Tsai-Ling Liao)*,Risk of mycobacterial disease among cancer patients: A population-based cohort study in a TB endemic area,Cancer Epidemiology,2019 Apr,59():64-70 2019 . 04
106 (Chun-Yu Chang)、(Chu-Huang Chen)、(Yi-Ming Chen)、(Tsu-Yi Hsieh)、(Ju-Pi Li)、沈明毅(Ming-Yi Shen)、藍忠亮(Joung-Liang Lan)*、陳得源(Der-Yuan Chen)*,Association between Negatively Charged Low-Density Lipoprotein L5 and Subclinical Atherosclerosis in Rheumatoid Arthritis Patients.,Journal of Clinical Medicine,2019 Feb,8(2):1-14 2019 . 02
107 (Tang KT)、(Hsieh TY)、(Chao YH)、(Li JP)、藍忠亮(Joung-Liang Lan)、林季千(Chi-Chien Lin)*、陳得源(Der-Yuan Chen)*,Apoptosis in patients with primary antiphospholipid antibody syndrome,International Journal of Rheumatic Diseases,2019 Feb,2(): 2019 . 02
108 林靖才(Ching-Tsai Lin)、黃文男(Wen-Nan Huang)、謝佳偉(Chia-Wei Hsieh)、陳一銘(Yi-Ming Chen)、陳得源(Der-Yuan Chen)、謝祖怡(Tsu-Yi Hsieh)、陳怡行(Yi-Hsing Chen)*,Safety and effectiveness of tocilizumab in treating patients with rheumatoid arthritis - A three-year study in Taiwan,JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION,2019 Feb,52(1):141-150 2019 . 02
109 (Yi-Ming Chen)、(Wen-Nan Huang)、(Tsai-Ling Liao)、(Jun-Pen Chen)、(Sheng-Shun Yang)、(Hsin-Hua Chen)、(Tsu-Yi Hsieh)、(Wei-Ting Hung)、(Yi-Hsing Chen)*、陳得源(Der-Yuan Chen)*,Comparisons of hepatitis C viral replication in patients with rheumatoid arthritis receiving tocilizumab, abatacept and tofacitinib therapy,ANNALS OF THE RHEUMATIC DISEASES,2019 Jan,0(0):1-2 2019 . 01
110 (Wan-Chun Chang)、(Mu-Tzu Chu)、(Chih-Yuan Hsu)、(Yeong-Jian Jan Wu)、(Jing-Yi Lee)、(Ting-Jui Chen)、(Wen-Hung Chung)、陳得源(Der-Yuan Chen)、(Shuen-Iu Hung)*,Rhein, An Anthraquinone Drug, Suppresses the NLRP3 Inflammasome and Macrophage Activation in Urate Crystal-Induced Gouty Inflammation,AMERICAN JOURNAL OF CHINESE MEDICINE,2019 Jan,47(1):135-151 2019 . 01
111 (Yi-Cheng Wang)、(Ming-Tsung Wu)、唐烽堯、陳得源(Der-Yuan Chen)、(Hsin-An Ko)、(Barry Shane)、(Wen-Nan Huang)、(En-Pei Isabel Chiang)*,MTHFR C677T polymorphism Increases MTX Sensitivity via the Inhibition of S-adenosylmethionine and De Novo Purine Synthesis,CLINICAL SCIENCE,2019 Jan,133(2):253-267 2019 . 01
112 陳一銘(Yi-Ming Chen)、楊孟純(Meng-Chun Yang)、陳得源(Der-Yuan Chen)*,Association between autophagy and inflammation in patients with rheumatoid arthritis receiving biologic therapy,ARTHRITIS RESEARCH & THERAPY,2018 Dec,20(1):268-279 2018 . 12
113 張詩欣(Shih-Hsin Chang)、陳得源(Der-Yuan Chen)*、陳韋成(Wei-Cheng Chen)、藍忠亮(Joung-Liang Lan)*,Clinical Characteristics of Rheumatoid Arthritis-Associated Lung Disease: A Retrospective Study in a Tertiary Referral Center in Taiwan,中華民國風濕病雜誌,2018 Dec,32(2):36-43 2018 . 12
114 廖采苓(Tsai-Ling Liao)、陳得源(Der-Yuan Chen)*、(Hsieh, Shie-Liang)*,Association of C-type lectin 18 levels with extrahepatic manifestations in chronic HCV infection,Scientific Reports,2018 Nov,8(1):1-11 2018 . 11
115 陳一銘(Yi-Ming Chen)、廖采苓(Tsai-Ling Liao)、陳信華(Hsin-Hua Chen)、陳得源(Der-Yuan Chen)*,Three months of once-weekly isoniazid plus rifapentine (3HP) in treating latent tuberculosis infection is feasible in patients with rheumatoid arthritis,ANNALS OF THE RHEUMATIC DISEASES,2018 Nov,77(11):1688-1689 2018 . 11
116 譚國棟(Kuo-Tung Tang)、張仕妮(Shih-Ni Chang)、陳得源(Der-Yuan Chen)*,Psoriatic patients with chronic viral hepatitis do not have an increased risk of liver cirrhosis despite long-term methotrexate use: Real-world data from a nationwide cohort study in Taiwan.,JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY,2018 Oct,79(4):652-658 2018 . 10
117 (Prasan Deep Rath)*、陳得源(Der-Yuan Chen),Anti-tumor necrosis factor biosimilars and intended copies in rheumatology: Perspective from the Asia Pacific region.,International Journal of Rheumatic Diseases,2018 Oct,0(0):1-16 2018 . 10
118 廖采苓(Tsai-Ling Liao)、陳得源(Der-Yuan Chen)*,Rituximab May Cause Increased Hepatitis C Virus Viremia in Rheumatoid Arthritis Patients Through Declining Exosomal MicroRNA-155,Arthritis & Rheumatology,2018 Aug,70(8):1209-1219 2018 . 08
119 (Hsin-Hua Chen)、(Wen-Cheng Chao)、(Tsai-Ling Liao)、(Ching-Heng Lin)*、陳得源(Der-Yuan Chen)*,Risk of autoimmune rheumatic diseases in patients with palindromic rheumatism: A nationwide, population-based, cohort study,PLoS One,2018 Jul,13(7):1-12 2018 . 07
120 黃德光(De-Kuang Hwang)、黃奕修(Yih-Shiou Hwang)、蔡明霖(Ming-Ling Tsai)、林純如(Chun-Ju Lin)、詹維鈞(Wei-Chun Chan)、張祐誠(Yo-Chen Chang)、陳得源(Der-Yuan Chen)、謝祖怡(Tsu-Yi Hsieh)、許淑娟(Shwu-Jiuan Sheu)*、林昌平(Chang-Ping Lin)*,Recommendation of using systemic anti-tumor necrosis factor-alpha for the treatment of noninfectious uveitis in Taiwan,Taiwan Journal of Ophthalmology,2018 Jul,8(3):117-120 2018 . 07
121 譚國棟(Kuo-Tung TANG)、陳得源(Der-Yuan Chen)*,Induction therapy for membranous lupus nephritis: a systematic review and network meta-analysis,International Journal of Rheumatic Diseases,2018 Jun,21(6):1163-1172 2018 . 06
122 (Chao YH)、陳得源、藍忠亮(Lan, Joung-Liang)、(Tan KT)*、林季千(Chi-Chien Lin)*,Tolerogenic β2-glycoprotein I DNA vaccine and FK506 as an adjuvant attenuates experimental obstetric antiphospholipid syndrome.,PLoS One,2018 Jun,13(6):e0198821 2018 . 06
123 林鍾泓(Chong Hong Lim)、陳得源(Der-Yuan Chen)*,The clinical application of tumor markers in the screening of malignancies and interstitial lung disease of dermatomyositis/polymyositis patients: A retrospective study,SAGE open medicine,2018 Jun,18(6):1-8 2018 . 06
124 周伯翰(Po-Han Chou)、(Kuo-TungTang)、(Yi-HsingChen)*、(Chia-WeiSun)、(Chih-MaoHuang)、陳得源(Der-Yuan Chen),Reduced frontal activity during a verbal fluency test in fibromyalgia: A near-infrared spectroscopy study.,JOURNAL OF CLINICAL NEUROSCIENCE,2018 Apr,50():35-40 2018 . 04
125 (I-Te Lee)*、(Wayne Huey-Herng Sheu)、(Wen-Jane Lee)、陳得源(Der-Yuan Chen),Serum brain-derived neurotrophic factor predicting reduction in pulse pressure after a one-hour rest in nurses working night shifts,Scientific Reports,2018 Apr,8():5485 2018 . 04
126 (Kuo-Lung Lai)、陳得源(Der-Yuan Chen)、(Mei-Chin Wen)、(Yi-Ming Chen)、(Wei-Ting Hung)、(Yi-Hsin Chen)、(Hsin-Hua Chen)*,What does power Doppler signal indicate in rheumatoid synovitis? A point of view from synovial histopathology,Journal of the Chinese Medical Association,2018 Apr,81(4):383-386 2018 . 04
127 陳得源(Der-Yuan Chen)、(YI?MING CHEN)、(HSIN?HUA CHEN)、(CHIA?WEI HSIEH)、(NING?RONG GUNG)、(WEI?TING HUNG)、(BOR?SHOW TZANG)*、(TSAI?CHING HSU),Human parvovirus B19 nonstructural protein NS1 activates NLRP3 inflammasome signaling in adult‑onset Still's disease,Molecular Medicine Reports,2018 Feb,17(2):3364-3371 2018 . 02
128 (Chia-Wei Hsieh)、(Chun-Yu Chang)、(Yi-Ming Chen)、(Hsin-Hua Chen)、(Wei-Ting Hung)、(Ning-Rong Gung)、(Shiow-Jiuan Wey)*、陳得源(Der-Yuan Chen)*,Impaired autophagic flux and its related inflammation in patients with adult-onset Still's disease.,Oncotarget,2018 Jan,9(1):110-121 2018 . 01
129 (Kuang-Hui YU)、陳得源(Der-Yuan Chen)、(Jiunn-Horng CHEN)、(Shih-Yang CHEN)、(Shyh-Ming CHEN)、(Tien-Tsai CHENG)、(Song-Chou HSIEH)、(Tsu-Yi HSIEH)、(Pai-Feng HSU)、(Chang-Fu KUO)、(Mei-Chuan KUO)、(Hing-Chung LAM)、(I-Te LEE)、(Toong-Hua LIANG)、(Hsiao-Yi LIN)、(Shih-Chang LIN)、(Wen-Pin TSAI)、蔡嘉哲(Jia-Zer Tsay)、魏正宗(Wei,Cheng-Chung)、(Chung-Han YANG)、(Wen-Chan TSAI)*,Management of gout and hyperuricemia: Multidisciplinary consensus in Taiwan,International Journal of Rheumatic Diseases,2018 Jan,21(4):772-787 2018 . 01
130 (Wen-Cheng Chao)、(Ching-Heng Lin)、(Tsai-Ling Liao)、(Yi-Ming Chen)、(Chiann-Yi Hsu)、(Jun-Peng Chen)、陳得源(Der-Yuan Chen)、(Hsin-Hua Chen)*,The risk of nontuberculous mycobacterial infection in patients with Sjögren's syndrome: a nationwide, population-based cohort study.,BMC INFECTIOUS DISEASES,2017 Dec,17(1):796-804 2017 . 12
131 (Yi-Ming Chen)、(Sheng-Shun Yang)、陳得源(Der-Yuan Chen)*,Risk-stratified management strategies for HBV reactivation in RA patients receiving biological and targeted therapy: A narrative review,JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION,2017 Nov,S1684-1182(17):30234-30237 2017 . 11
132 (Lin, Y.K.)、陳得源*、林妍如(Lin, Blossom Yen-Ju)*,Determinants and effects of medical students' core self-evaluation tendencies on clinical competence and workplace well-being in clerkship,PLoS One,2017 Nov,12(11):e0188651 2017 . 11
133 (Yi-Ming Chen)、(Hsin-Hua Chen)、(Wen-Nan Huang)、(Tsai-Ling Liao2)、(Jun-Peng Chen)、(Wen-Cheng Chao)、(Ching-Tsai Lin)、(Wei-Ting Hung)、(Chia-Wei Hsieh)、(Tsu-Yi Hsieh)、(, Yi-Hsing Chen)、陳得源(Der-Yuan Chen)*,Tocilizumab potentially prevents bone loss in patients with anticitrullinated protein antibody-positive rheumatoid arthritis.,PLoS One,2017 Nov,12(17):1-13 2017 . 11
134 (Wei-Chiao Chen)、(Wen-Chang Wang)、(Hsing-Fang Lu)、(Yukinori Okada)、(Wei-Pin Chang)、(Yii-Her Chou)、(Hui-Hua Chang)、(Jin-Ding Huang)、陳得源(Der-Yuan Chen)*、(Wei-Chiao Chang)*,rs2841277 (PLD4) is associated with susceptibility and rs4672495 is associated with disease activity in rheumatoid arthritis,Oncotarget,2017 Sep,8(64):64180-64190 2017 . 09
135 陳得源(Der-Yuan Chen)、林季千(Chi-Chien Lin)、(Chen YM)、(Chao Yh)、(Yang DH)*,Dextromethorphan Exhibits Anti-inflammatory and Immunomodulatory Effects in a Murine Model of Collagen-Induced Arthritis and in Human Rheumatoid Arthritis,Scientific Reports,2017 Sep,12(7):11353 2017 . 09
136 林季千(Chi-Chien Lin)、陳得源(Der-Yuan Chen)、(Tan KT)、(Chao YH)、(Shen CH)、(Lui PW)*,Inhibitory effects of propofol on Th17 cell differentiation,IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY,2017 Aug,39(4):211-218 2017 . 08
137 (Tsai-Ling Liao)、(Ching-Heng Lin)、(Hsin-Hua Chen)、(Yi-Ming Chen)、(Che-Chen Lin)、陳得源(Der-Yuan Chen)*,Significant Associations of Neurological Complications of Herpes Zoster With Stroke in Rheumatoid Arthritis Patients,Journal of the American Heart Association,2017 Jul,6(7):1-17 2017 . 07
138 (Tsai-Ling Liao)、(Yi-Ming Chen)、(Hung-Jen Liu)、陳得源(Der-Yuan Chen)*,Risk and severity of herpes zoster in patients with rheumatoid arthritis receiving different immunosuppressive medications: a case–control study in Asia,BMJ Open,2017 Jun,7(1):1-10 2017 . 06
139 (Tsai-Ling Liao)、(Yi-Ming Chen)、(Chia-Wei Hsieh)、(Hsin-Hua Chen)、(Hsiu-Chin Lee)、(Wei-Ting Hung)、(Kuo-Tung Tang)、陳得源(Der-Yuan Chen)*,Upregulation of circulating microRNA-134 in adult-onset Still’s disease and its use as potential biomarker,Scientific Reports,2017 Jun,7(1):4214-4226 2017 . 06
140 (Kuo-Tung Tang)、(Tsu-Yi Hsieh)、(Ya-Hsuan Chao)、(Meng-Xian Lin)、(Yi-Hsing Chen)、陳得源(Der-Yuan Chen)*、(Chi-Chen Lin)*,Plasma levels of high-mobility group box 1 and soluble receptor for advanced glycation end products in primary antiphospholipid antibody syndrome patients,PLoS One,2017 May,12(5):1-13 2017 . 05
141 (Wen-Cheng Chao)、(Ching-Heng Lin)、(Tsai-Ling Liao)、(Yi-Ming Chen)、陳得源(Der-Yuan Chen)*、(Hsin-Hua Chen)*,Association between a history of mycobacterial infection and the risk of newly diagnosed SjoÈgren's syndrome: A nationwide, population-based case-control study,PLoS One,2017 May,12(5):1-11 2017 . 05
142 (Chia-Wei Hsieh)、(Yi-Ming Chen)、(Chi-Chen Lin)、(Kuo-Tung Tang)、(Hsin-Hua Chen)、(Wei-Ting Hung)、(Kuo-Lung Lai)、陳得源(Der-Yuan Chen)*,Elevated Expression of the NLRP3 Inflammasome and Its Correlation with Disease Activity in Adult-onset Still Disease,JOURNAL OF RHEUMATOLOGY,2017 Apr,44(8):1142-1150 2017 . 04
143 陳得源(Der-Yuan Chen)、(Yi-Ming Chen)、(Han-Ju Chien)、(Chi-Chen Lin)、(ChiaWei Hsieh)、(Hsin-Hua Chen)、(Wei-Ting Hung)、(Chien-Chen Lai)*,Metabolic Disturbances in Adult-Onset Still’s Disease Evaluated Using Liquid Chromatography/Mass Spectrometry-Based Metabolomic Analysis,PLoS One,2016 Dec,11(12): 2016 . 12
144 陳得源(Der-Yuan Chen)、李如璧(Ju-Pi Li)、(Y.-M. Chen)、(T.-L. Liao)、(H.-H. Chen)、(C.-W. Hsieh)、(W.-Y. Yeh)、藍忠亮(Joung-Liang Lan)*,Elevated Neopterin Levels Are Associated with Increased Tuberculosis Risk in Rheumatoid Arthritis Patients with QuantiFERON Conversion during Biologic Therapy,PLoS One,2016 Nov,11(11):e0166301 2016 . 11
145 陳得源(Der-Yuan Chen)、(Ching-Heng Lin)、(Yi-Ming Chen)、(HsinHua Chen)*,Risk of Atrial Fibrillation or Flutter Associated with Periodontitis: A Nationwide, Population-Based, Cohort Study.,PLoS One,2016 Oct,11(10): 2016 . 10
146 (T.-L. Liao)、(Y.-M. Chen)、陳得源(Der-Yuan Chen)*,Risk factors for cryptococcal infection among patients with rheumatoid arthritis receiving different immunosuppressive medications.,CLINICAL MICROBIOLOGY AND INFECTION,2016 Sep,22(9): 2016 . 09
147 (Huai-Chia Chuang)、(Yi-Ming Chen)、(Wei-Ting Hung)、李如璧(Ju-Pi Li)、陳得源(Der-Yuan Chen)、藍忠亮(Joung-Liang Lan)*、(Tse-Hua Tan)*,Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis,Oncotarget,2016 Aug,5():11419 2016 . 08
148 (Tsai-Ling Liao)、(Chin-Fu Lin)、陳一銘(Yi-Ming Chen)、(Hung-Jen Liu)、陳得源(Der-Yuan Chen)*,Risk Factors and Outcomes of Nontuberculous Mycobacterial Disease among Rheumatoid Arthritis Patients: A Case-Control study in a TB Endemic Area.,Scientific Reports,2016 Jul,11(6):29443 2016 . 07
149 陳得源(Der-Yuan Chen)*、陳一銘(Yi-Ming Chen)、(Tsu-Yi Hsieh)、(Wei-Ting Hung)、(Chia-Wei Hsieh)、(Hsin-Hua Chen)、(Kuo-Tung Tang)、藍忠亮(Joung-Liang Lan),Drug trough levels predict therapeutic responses to dose reduction of adalimumab for rheumatoid arthritis patients during 24 weeks of follow-up.,RHEUMATOLOGY,2016 Jun,55(1):143-148 2016 . 06
150 (Tsai-Ling Liao)、(Ching-Heng Lin)、(Yi-Ming Chen)、(Chia-Li Chang)、(HsinHua Chen)、陳得源(Der-Yuan Chen)*,Different Risk of Tuberculosis and Efficacy of Isoniazid Prophylaxis in Rheumatoid Arthritis Patients with Biologic Therapy: A Nationwide Retrospective Cohort Study in Taiwan,PLoS One,2016 Apr,11(4): 2016 . 04
151 (Kuo-Tung Tang)、(Wei-Ting Hung)、(Yi-Hsing Chen)、(Ching-Heng Lin)*、陳得源(Der-Yuan Chen)*,Methotrexate is not associated with increased liver cirrhosis in a population-based cohort of rheumatoid arthritis patients with chronic hepatitis B,Scientific Reports,2016 Mar,(6):22387 2016 . 03
152 (Kuo-Tung Tang)、(Ching-Heng Lin)、(HH Chen)、(Yi-Hsing Chen)、陳得源(Der-Yuan Chen)*,Suicidal drug overdose in patients with systemic lupus erythematosus, a nationwide population-based case-control study,LUPUS,2016 Feb,25(2):199-203 2016 . 02
153 陳得源(Der-Yuan Chen)*、(Yi-Ming Chen)、(Wei-Ting Hung)、(Hsin-Hua Chen)、(Chia-Wei Hsieh)、(Yi-Hsing Chen)、(Wen-Nan Huang)、(Tsu-Yi Hsieh),Immunogenicity, drug trough levels and therapeutic response in patients with rheumatoid arthritis or ankylosing spondylitis after 24-week golimumab treatment.,ANNALS OF THE RHEUMATIC DISEASES,2015 Dec,74(12):2261-2264 2015 . 12
154 (Hsin-Hua Chen)、(Yi-Ming Chen)、(Kuo-Lung Lai)、(Ching-Heng Lin)、(Chao-Hsiung Tang)、陳得源(Der-Yuan Chen)*,Factors affecting discontinuation of adalimumab and etanercept therapy in anti-TNF-naïve patients with ankylosing spondylitis: Nationwide population-based cohort study,Modern Rheumatology,2015 Nov,25(6):903-907 2015 . 11
155 (Tsai-Ling Liao)、(Ching-Heng Lin)、(Gwan-Han Shen)、(Chia-Li Chang)、(Chin-Fu Lin)、陳得源(Der-Yuan Chen)*,Risk for Mycobacterial Disease among Patients with Rheumatoid Arthritis, Taiwan, 2001-2011.,EMERGING INFECTIOUS DISEASES,2015 Aug,21(8):1387-1395 2015 . 08
156 陳得源(Der-Yuan Chen)*、(Yi-Ming Chen),Response to: 'Towards optimal cut-off trough levels of adalimumab and etanercept for a good therapeutic response in rheumatoid arthritis. Results of the INMUNOREMAR study' by Sanmarti et al.,ANNALS OF THE RHEUMATIC DISEASES,2015 Aug,74(8): 2015 . 08
157 (H.-H. Chen)、(Tsai LJ)、(Lee KR)、(Chen YM)、(Hung WT)、陳得源(Der-Yuan Chen)*,Genetic association of complement component 2 polymorphism with systemic lupus erythematosus,TISSUE ANTIGENS,2015 Aug,86(2):122-133 2015 . 08
158 (Yi-Ming Chen)、(Ching-Heng Lin)、(Tsuo-Hung Lan)、(Hsin-Hua Chen)、張仕妮(Shih-Ni Chang)、(Yi-Hsing Chen)、(Jun-Sing Wang)、(Wei-Ting Hung)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)*,Hydroxychloroquine reduces risk of incident diabetes mellitus in lupus patients in a dose-dependent manner: a population-based cohort study,RHEUMATOLOGY,2015 Jul,54(7):1244-1249 2015 . 07
159 陳得源(Der-Yuan Chen)*、(Yi-Ming Chen)、(Chi-Chen Lin)、(Chia-Wei Hsieh)、(Yen-Ching Wu)、(Wei-Ting Hung)、(Hsin-Hua Chen)、藍忠亮(Joung-Liang Lan),The potential role of advanced glycation end products (AGEs) and soluble receptors for AGEs (sRAGE) in the pathogenesis of adult-onset still’s disease,BMC MUSCULOSKELETAL DISORDERS,2015 May,16(111):1-9 2015 . 05
160 陳得源(Der-Yuan Chen)*、(Yi-Ming Chen)、(Tsu-Yi Hsieh)、Chia-Wei Hsi、(Chi-Chen Lin)、藍忠亮(Joung-Liang Lan),Significant effects of biologic therapy on lipid profiles and insulin resistance in patients with rheumatoid arthritis,ARTHRITIS RESEARCH & THERAPY,2015 Mar,17(): 2015 . 03
161 吳丞斌(Cheng-Pin Wu)、(Chia-Wei Hsieh)*、陳得源、(Bor-Jen Lee)、(Chii-Shuenn Yang),Tocilizumab-associated cutaneous reactive endotheliomatosis in a patient with rheumatoid arthritis,JOINT BONE SPINE,2015 ,82():132-134 2015 .
162 陳一銘(Yi-Ming Chen)、莊懷佳(Huai-Chia Chuang)、(Wen-Chun Lin)、(Ching-Yi Tsai)、(Chia-Wei Wu)、(Ning-Rong Gong)、(Wei-Ting Hung)、(Tsuo-Hung Lan)、藍忠亮(Joung-Liang Lan)*、譚澤華*、陳得源(Der-Yuan Chen)*,Germinal Center Kinase–like Kinase Overexpression in T Cells as a Novel Biomarker in Rheumatoid Arthritis,ARTHRITIS AND RHEUMATISM,2013 Oct,65(10):2573-2582 2013 . 10
163 陳得源(Der-Yuan Chen)、(Pei-Shan Song)、(Jau-Shyong Hong)、(Ching-Liang Chu)、(I-Horng Pan)、(Yi-Ming Chen)、(Ching-Hsiung Lin)、(Sheng-Hao Lin)、(Chi-Chen Lin)*,Dextromethorphan Inhibits Activations and Functions in Dendritic Cells,Clinical & Developmental Immunology,2013 May,2013(2013):125643 2013 . 05
164 (Huai-Chia Chuang)、藍忠亮(Joung-Liang Lan)、陳得源(Der-Yuan Chen)、(Chia-Yu Yang)、(Yi-Ming Chen)、(Ju-Pi Li)、(Ching-Yu Huang)、(Pao-En Liu)、(Xiaohong Wang)、(Tse-Hua Tan)*,The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells,NATURE IMMUNOLOGY,2011 Nov,12(11):1113-1118 2011 . 11
165 陳得源(Der-Yuan Chen)、(Hui-Min Chih)、藍忠亮(Joung-Liang Lan)、(Hsin-Yueh Chang)、(Wei-Wen Chen)、(En-Pei Isabel Chiang)*,Blood lipid profiles and peripheral blood mononuclear cell cholesterol metabolism gene expression in patients with and without methotrexate treatment,BMC Medicine,2011 Jan,9(4): 2011 . 01

研討會論文

研討會論文/Conference Papers
(發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目)
日期
1 Anti-SNRK and anti-HUWE1 antibodies as the potential biomarkers for predicting good response to tofacitinib therapy in rheumatoid arthritis patients,2024年中華民國風濕病醫學會會員大會暨學術研討會,新竹喜來登大飯店3樓海報區,2024.12.14~2024.12.15, 2024 . 12
2 Serial Anti-MDA5 Antibody Levels correlates with disease activity and outcome in Dermatomyositis-Associated Interstitial Lung Disease,2024年中華民國風濕病醫學會會員大會暨學術研討會,新竹喜來登大飯店3樓海報區,2024.12.14~2024.12.15, 2024 . 12
3 Anti-Ro52/SSA antibody and disease duration as predictive markers for the development of pulmonary arterial hypertension in connective tissue disease patients with interstitial lung disease,2024年中華民國風濕病醫學會會員大會暨學術研討會,新竹喜來登大飯店3樓海報區,2024.12.14~2024.12.15, 2024 . 12
4 ,中華民國風濕病醫學會2024年會員大會暨學術研討會,新竹喜來登大飯店3樓宴會廳,2024.12.14~2024.12.15,The potential markers for predicting therapeutic response to b/tsDMARDs in rheumatic diseases Smart Anti-Inflammation: Personalized Precision Treatment Testing for Rheumatoid Arthritis 2024 . 12
5 即刻診斷與補體抑制劑治療:在懷孕誘發的非典型溶血性尿毒症候群併多重器官衰竭中的救援策略Rapid Diagnosis and Eculizumab: A Lifesaving Strategy in Pregnancy-Associated aHUS with Multi-Organ Failure,台灣內科醫學會113年會員大會暨學術演講會,台大醫院國際會議中心,2024.11.30~2024.12.01, 2024 . 11
6 Elevated triglyceride-glucose (TyG) index level in non-diabetic rheumatoid arthritis patients: as a potential predictor of the 10-year probability of cardiovascular disease,社團法人中華民國風濕病醫學會-112年年會,台南香格里拉飯店,2023.11.25~2023.11.26, 2023 . 11
7 Automatic scoring of ultrasound synovial hypertrophy in rheumatoid arthritis through integrating multiple convolutional neural network models,EULAR 2023 European Congress of Rheumatology,MiCo Center, Milan, Italy,2023.05.31~2023.06.03, 2023 . 05
8 Mirabegron is more tolerable than solifenacin in Sjogren’s syndrome patients with OAB,38th Annual European Association of Urology Congress,米蘭,2023.03.10~2023.03.13, 2023 . 03
9 Baseline ANA and anti-Ro/SSA antibody as potential predictive markers for drug immunogenicity and poor EULAR response in adalimumab-treated rheumatoid arthritis patients,中華民國風濕病醫學會 2022 年會,臺北萬豪酒店5樓,2022.10.15~2022.10.16, 2022 . 10
10 結節性多動脈炎以自發性肝內動脈出血、雙側腎梗塞以及缺血性腸炎併發腸穿孔為表現,中華民國風濕病醫學會2022年學術研討會,台北萬豪酒店,2022.10.15~2022.10.15, 2022 . 10
11 非以乾燥症狀初發之修格蘭氏症候群相關間質性肺病,社團法人中華民國風濕病醫學會40周年會員大會暨學術研討會,台北萬豪酒店,2022.10.15~2022.10.16, 2022 . 10
12 The Side Effects of Hydroxychloroquine: From the Mechanism to the Perspective of Chinese Medicine,Ethnopharmacology 2022,中國醫藥大學水湳總校區國際會議廳,2022.05.28~2022.05.31, 2022 . 05
13 ,中華民國風濕病醫學會 中區月會,全國大飯店B1樓貴賓廳,2022.03.25~2022.03.25,Immunogenicity of SARS-CoV-2 vaccines in rheumatic diseases. 2022 . 03
14 肥大細胞增生症合併乾癬之特殊表現於一位56歲女性,2021年風濕病醫學會年會,因疫情改成線上舉辦,2021.10.30~2021.10.31, 2021 . 10
15 Anti-Isoleucyl-tRNA synthetase (OJ) autoantibodies in Taiwanese Patients with Inflammatory Myopathies and Interstitial Lung disease: underdetected but not rare,2021年中華民國風濕病醫學會年會,線上會議,2021.10.29~2021.10.31, 2021 . 10
16 微小RNA-223藉由調節鈣流入與外泌體傳遞來抑制成人型史笛兒氏症患者之嗜中性球細胞外網,2021年中華民國風濕病醫學會年會,線上會議,2021.10.29~2021.10.31, 2021 . 10
17 The effectiveness of tocilizumab in treating refractory adult-onset Still’s disease with dichotomous phenotypes: IL-18 is a potential predictor of therapeutic response,2021年中華民國風濕病醫學會年會,線上會議,2021.10.29~2021.10.31, 2021 . 10
18 ,2020社團法人中華民國風濕病學會會員大會暨學術研討會,台北新板希爾頓酒店,2020.10.31~2020.11.1 , 2020 . 10
19 Life expectancy, loss of life expectancy and healthcare expenditures for rheumatoid arthritis in the era of biologics-A nationwide cohort followed for 14 years,中華民國風濕病醫學會第38周年會員大會暨學術研討會,新北市,2020.10.30~2020.11.1 , 2020 . 10
20 動脈血管鈣化病變發生在一位帶有抗磷脂質自體抗體和反覆腳多處潰瘍的病人,2020社團法人中華民國風濕病醫學會會員大會暨學術研討會,台北新板希爾頓酒店,2020.10.31~2020.11.1 , 2020 . 10
21 潛伏結核感染病人之分枝桿菌活存係由微小RNA-889針對TWEAK分子而抑制細胞自我吞噬,109年度會員大會暨學術研討會,台大醫院國際會議中心,2020.10.24~2020.10.25, 2020 . 10
22 結合血液檢測之長鏈非編碼核糖核酸與細胞激素的分類模式可用來診斷成人型史笛兒氏症及預測其疾病病程,2020社團法人中華民國風濕病學會會員大會暨學術研討會,台北新板希爾頓酒店,2020.10.30~2020.11.1 , 2020 . 10
23 Hydroxychloroquine enhances efferocytosis and inhibits IL-6 and TNF-α productions through upregulating both Gas6/Axl and MFG-E8/TG2 Signaling pathways in Pristine-induced lupus mice,The American Association of Immunologists,線上會議,2020.05.8 ~2020.05.12, 2020 . 05
24 A case of deformed arthritis, limited type cutaneous sclerosis and UIP lung,中華⺠國風濕病醫學會第37週年年會,台南大員皇冠假日酒店,2019.12.14~2019.12.15, 2019 . 12
25 Periungual bullae in a case of pemphigus,中華⺠國風濕病醫學會第37週年年會,台南大員皇冠假日酒店,2019.12.14~2019.12.15, 2019 . 12
26 TIF1 gamma抗體陽性的成人皮肌炎患者之皮膚鈣化,2019年中華民國風濕病醫學會年會,台南大員皇冠酒店,2019.12.13~2019.12.15, 2019 . 12
27 ,2019 社團法人中華民國風濕病醫學會會員大會暨學術研討會,台南大員皇冠假日酒店,2019.12.13~2019.12.15,Clinical Research in a Rheumatologist: from bedside to bench 2019 . 12
28 An association of gut microbiota with different phenotypes in rheumatoid arthritis patients in Taiwan,中華民國風濕病醫學會第37 週年年會,台南大員皇冠酒店3 樓I+II+III 會議室,2019.12.13~2019.12.15, 2019 . 12
29 Calciphylaxis in End Stage Lupus Nephritis,中華民國風濕病醫學會2019年會,台南大員皇冠假日酒店,2019.12.14~2019.12.15, 2019 . 12
30 Anti-MDA5 antibody-positive dermatomyositis with interstitial lung disease and pneumomediastinum treated with multi-target therapy including anti-fibrotic agent – case report and literature review,中華⺠國風濕病醫學會第37週年年會,台南大員皇冠假日酒店,2019.12.13~2019.12.15, 2019 . 12
31 Clinical Images: Efficacy and safety of tofacitinib in the treatment of alopecia totalis with chronic hepatitis B virus infection,中華民國風濕病醫學會2019年會,台南大員皇冠酒店2樓宴會廳,2019.12.13~2019.12.15, 2019 . 12
32 抗RNA聚合酶III抗體陽性硬皮症腎危象經附加血漿置換治療:一病例報告,台灣內科醫學會會員大會暨學術演講會,台大醫院國際會議中心 (台北市徐州路2號),2019.11.30~2019.12.01, 2019 . 11
33 Identification of the novel biomarkers for connective tissue disease-related interstitial lung diseases,JCR International School 2019,Asama International Conference Hall, Karuizawa Prince Hotel West, Nagano, Japan,2019.07.25~2019.07.27, 2019 . 07
34 Significant Response to Immunomodulatory Combination Therapy for Recurrent Kimura’s Disease: A Case Report.,21th Asia Pacific League of Associations for Rheumatology Congress,BRISBANE CONVENTION & EXHIBITION CENTRE,2019.04.08~2019.04.11, 2019 . 04
35 ,中華民國風濕病醫學會中區月會,全國飯店 B1 貴賓廳,2018.12.22~2018.12.28,Case Sharing-Idiopathic Angioedema in a 46-year-old Woman. 2018 . 12
36 莫須瘤藉由降低外分泌體之微小核醣核酸-155來引起類風濕關節炎病人C型肝炎病毒量之增加,中華民國免疫學會2018年會員大會暨學術研討會,張榮發基金會國際會議中心,2018.10.28~2018.10.28, 2018 . 10
37 Cytomegalovirus Induced Hemophagocytic Lymphohistiocytosis Mimicking Systemic Lupus Erythematosus: A Case Report.,20th Asia Pacific League of Associations for Rheumatology Congress,高雄展覽館,2018.09.06~2018.09.09, 2018 . 09
38 ,20th Asia Pacific League of Associations for Rheumatology Congress,Kaohsiung Exhibition Centre,2018.09.06~2018.09.09, 2018 . 09
39 ,20th Asia Pacific League of Associations for Rheumatology Congress (APLAR 2018),Kaohsiung Exhibition Centre,2018.09.06~2018.09.09,New insights into immunopathogenesis in adult-onset Still’s disease, an autoinflammatory disease 2018 . 09
40 Screening natural products and drugs for the therapy of autoimmune diseases by efferocytosis,Asia Pacific League of Associations for Rheumatology,Kaohsiung,2018.09.06~2018.09.09, 2018 . 09
41 Canakinumab for the treatment of refractory systemic juvenile idiopathic arthritis: a case sharing and review.,中華民國風濕病醫學會 中區月會,台中金典酒店13樓玫瑰一廳,2018.03.24~2018.03.24, 2018 . 03

專書

暫無資料

研究計畫

研究計畫/Research Grant
(研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,計畫期間)
日期
1 整合型(召集人、總主持人),NSTC 113-2218-E-039-001,陳健尉、黃文男、張啟聖、許凱程、黃建中(Huang, Chien-Chung)、陳柏谷(Po-Ku Chen)、陳一銘,科技部,利用全基因體定序、胜肽體、外泌體及微型核醣核酸剖繪之人工智慧分析,創新開發「智抗炎」晶片,選出類風濕性關節炎患者最適藥物之精準醫療(3/3),2024.8.1~2025.7.31 2024 . 08
2 臨床試驗與研究計畫,CMUH110-REC1-042,藍忠亮(Joung-Liang Lan),,以異體脂肪組織幹細胞治療結締組織疾病患者併發間質性肺病變之第I/IIa期臨床試驗,2024.1.1~2024.12.31 2024 . 01
3 個別型,CMUHCH-DMR-113-013,陳得源(Der-Yuan Chen),附醫院內計畫,以多組學分析探討纖維肌痛症之病理機轉及免疫標記,2023.9.1~2024.8.31 2023 . 09
4 個別型,NSTC 112-2314-B-039-067,林季千、蔣恩沛,科技部,利用脂質體學分析平台與生物醫學模式探求類風濕關節炎發生早發性動脈硬化之新穎生物標誌與治療標靶(3/3),2023.8.1~2024.7.31 2023 . 08
5 個別型,DMR-113-119,陳得源(Der-Yuan Chen),本校(含附醫),骨髓來源的抑制細胞與風濕疾病患者疾病活動度指標及其感染之關聯性,2023.8.1~2024.7.31 2023 . 08
6 整合型(召集人、總主持人),NSTC 112-2218-E-039-001,陳健尉、黃文男、張啟聖、許凱程(HSU KAI-CHENG)、黃建中(Huang, Chien-Chung)、陳柏谷(PoKu Chen)、陳一銘,科技部,利用全基因體定序、胜肽體、外泌體及微型核醣核酸剖繪之人工智慧分析,創新開發「智抗炎」晶片,選出類風濕性關節炎患者最適藥物之精準醫療(2/3),2023.8.1~2024.7.31 2023 . 08
7 個別型,DMR-113-011,陳柏谷(PoKu Chen),附醫院內計畫,異體脂肪組織幹細胞治療對於結締組織疾病併發間質性肺病變患者免疫反應的影響,2023.8.1~2024.7.31 2023 . 08
8 整合型(召集人、總主持人),NSTC 111-2218-E-039-001,陳健尉、黃文男、張啟聖、許凱程(HSU KAI-CHENG)、黃建中(Huang, Chien-Chung)、陳柏谷(PoKu Chen)、陳一銘,科技部,利用全基因體定序、胜肽體、外泌體及微型核醣核酸剖繪之人工智慧分析,創新開發「智抗炎」晶片,選出類風濕性關節炎患者最適藥物之精準醫療(1/3),2022.8.1~2023.7.31 2022 . 08
9 個別型,MOST 111-2314-B-039-010,陳得源(Der-Yuan Chen)、彭成元(Peng, Cheng-Yuan),科技部,利用生物醫學模式探求風濕病患者發生非酒精性脂肪肝病變之新穎生物標誌與治療標靶,2022.8.1~2023.7.31 2022 . 08
10 個別型,MOST 111-2314-B-039-011,林季千、蔣恩沛,科技部,利用脂質體學分析平台與生物醫學模式探求類風濕關節炎發生早發性動脈硬化之新穎生物標誌與治療標靶(2/3),2022.8.1~2023.7.31 2022 . 08
11 個別型,MOST 110-2314-B-039-051,林季千、蔣恩沛,科技部,利用脂質體學分析平台與生物醫學模式探求類風濕關節炎發生早發性動脈硬化之新穎生物標誌與治療標靶(1/3),2021.8.1~2022.7.31 2021 . 08
12 個別型,DMR-110-021,黃柏豪(Po-Hao Huang)、陳柏谷(PoKu Chen),附醫院內計畫,風濕疾病患者高鐵蛋白血症之致病機制及新冠狀病毒感染之關聯性,2020.8.1~2021.7.31 2020 . 08
13 個別型,DMR-109-171,陳得源(Der-Yuan Chen),附醫院內計畫,類風濕關節炎併發間質性肺病變之機制探討及其生物標誌,2019.8.1~2020.6.30 2019 . 08
14 個別型,DMR-109-172,陳得源(Der-Yuan Chen),附醫院內計畫,類風溼性關節炎病人使用Abatacept後對於homocysteine和adipokine的影響,2019.8.1~2020.6.30 2019 . 08
15 個別型,DMR-108-165,陳得源(Der-Yuan Chen),附醫院內計畫,半乳糖凝集素與C-型凝集素在自體發炎疾病之致病角色及與發炎小體關聯性,2018.8.1~2019.6.30 2018 . 08
16 個別型,MOST 107-2314-B-039-053-MY3,廖采苓、陳一銘,科技部,嗜中性白血球細胞外網在自體發炎病-成人型史笛兒氏症致病角色及其轉譯應用,2018.8.1~2019.7.31 2018 . 08
17 個別型,微型核糖核酸在類風濕性關節炎患者結核病感染之致病角色(III),陳得源(Der-Yuan Chen)、陳一銘,科技部,微型核糖核酸在類風濕性關節炎患者結核病感染之致病角色(III),2018.8.1~2019.7.31 2018 . 08
18 個別型,MOST 104-2314-B-039-060-MY3,徐再靜(Hsu TC)、林季千(Lin CC)、陳一銘(Yi-Ming Chen),科技部,細胞自體吞噬在自體發炎疾病-成人型史笛兒氏症之致病角色及其免疫調控,2017.8.1~2018.7.31 2017 . 08

專利技術

專利/Patent
(專利名稱,專利類別,專利國別,專利號碼,專利期間)
日期
1 診斷及分型成人發作行史迪兒症之方法,發明專利,台灣,I755750,2022.2.21~2040.6.9 2022 . 02
2 檢測成人發作型史笛兒氏症之罹病風險及預後之方法,發明專利,台灣,I679279,2019.12.11~2038.5.8 2019 . 12
3 新穎結核病生物標誌物、以之評估結核病發生風險、治療效果及其預後之方法,發明專利,台灣,I674409,2019.10.11~2038.5.15 2019 . 10
4 Method for Detecting the Risk and Prognosis of Adult-Onset Still’s Disease,發明專利,美國,US 11,047,012 B2,2018.6.29~2038.6.20 2018 . 06
5 牛樟芝萃取物用於製備調節Th17細胞之藥物的用途 USE OF AN ANTRODIA CINNAMOMEA (ANTRODIA CAMPHORATA OR TAIWANOFUNGUS CAMPHORATUS) EXTRACT FOR PREPARING A DRUG FOR MODULATING Th17 CELLS,發明專利,台灣,I527586,2016.4.1~2033.8.12 2016 . 04

獲獎事蹟

獲獎/Award
(獲獎名稱,給獎單位,獲獎日期)
日期
1 APLAR MASTER AWARD 2024,Asia-Pacific League of Associations for Rheumatology (APLAR),2024.8.22 2024 . 08
2 中華民國風濕病學會第38屆學術研討會-陳正言教授最佳年會論文獎,社團法人中華民國風濕病學會,2021.10.31 2021 . 10
3 社團法人中華民國風濕病醫學會2021學術研討會優秀論文獎,社團法人中華民國風濕病醫學會,2021.10.31 2021 . 10
4 中華民國風濕病醫學會第38屆學術研討會青年論文優秀論文獎第一名,中華民國風濕病醫學會,2021.10.31 2021 . 10
5 109年度財團法人沈水德翁文教基金會優秀論文獎,中華民國免疫學會,2020.10.25 2020 . 10
6 中華民國風濕病醫學會第37屆會員大會暨學術研討會-優秀論文獎第一名,社團法人中華民國風濕病醫學會,2019.12.15 2019 . 12
7 台灣人工智慧學校台中分校第三期專業經理人專題競賽,台灣人工智慧學校,2019.9.28 2019 . 09
8 107年財團法人沈水德翁文教基金會優秀論文獎,中華民國免疫學會,2018.10.28 2018 . 10

技術轉移

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