Drug component

Prophylactic administration

Contraindications and precautions

Doxycycline

100mg once a day (1 tablet)

Start taking it 1-2 days before reaching the high-risk area, and continue taking it for 28 days after leaving the high-risk area.

Contraindications: Pregnant women, children under 8 years old, breast-feeding women, patients with liver dysfunction.

Side effects: Skin photosensitivity (sun protection recommended), stomachache.

Hydroxy-chloroquine

400mg once a week (2 tablets)

Start taking it two weeks before reaching the high-risk area and for four weeks after leaving the high-risk area. Most areas are resistant to the drug.

Contraindications: Pregnant women, patients with retinopathy, lactating women, patients with psoriasis and G6PD deficiency, children.

Side effects: Blurred vision, skin rash, nausea and dysentery.

(Malarone^®)

1 tablet a day (atovaquone 250 / proquanil 100 mg)

Start taking it 1-2 days before reaching the high-risk area, and continue taking it for 7 days after leaving the high-risk area.

Contraindications: Pregnant and lactating women, patients with severe renal insufficiency, people under 40 kg.

Side effects: Headache, nausea, vomiting, stomachache, diarrhea, loss of appetite.

Mefloquine

250 mg once a week (1 tablet)

Start taking it 1-2 weeks before reaching the high-risk area, and continue taking it for 4 weeks after leaving the high-risk area.

Contraindications: Patients with mental illness, history of epilepsy, arrhythmia, and women in the first three months of pregnancy.

Side effects: Nausea, vomiting, dizziness, headache, insomnia.