醫師介紹
醫師學術論文
Paper
蔡銘駿 Ming-Jun Tsai 主治醫師
蔡銘駿醫師於高雄醫學大學附設醫院接受完整的神經內科訓練,並取得神經內科專科醫師執照,之後續擔任高醫與本院神經內科主治醫師。期間陸續發表臨床及基礎醫學之論文,也因此獲選收錄於 2006 年世界名人錄 (Who’s Who in the World) 中。蔡醫師專長於腦中風及神經藥物不良反應診療。 蔡醫師研究專注於腦中風,神經藥理及神經科疾病相關動物模式之開發,並於國立成功大學基礎醫學研究所取得博士學位。
學術機構典藏
論文
期刊論文
期刊論文/Journal Paper (作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄) |
日期 | |
1 | (Muhammad Suhail)、(Hamid Ullah)、(Quoc Lam Vu)、(Arshad Khan)、蔡銘駿(Ming-Jun Tsai)*、(Pao-Chu Wu)*,Preparation of pH-responsive hydrogels based on chondroitin sulfate/alginate for oral drug delivery,Pharmaceutics,2022 Oct,14(2110): | 2022 . 10 |
2 | 溫啟邦(Chi-Pang Wen)、(Wi-Che Lee)、(Yuan-Ting Sun)、(Chih-Yuan Huang)、蔡崇豪(Chon-Haw Tsai)、(Po-Lin Chen)、(Wei-Lun Chang)、(Po-Yen Yeh)、(Cheng-Yu Wei)、蔡銘駿(Ming-Jun Tsai)、(Yu Sun)、(Chih-Hao Lin)、(Jiunn-Tay Lee)、(Ta-Chang Lai)、(Li-Ming Lien)、林橙莉(Cheng-Li Lin)、林美辰(Mei-Chen Lin)、(June-Han Lee)、(Hao-Kuang Wang)*、許重義(Chung Y. Hsu),Low-density lipoprotein cholesterol and mortality in patients with intracerebral hemorrhage in Taiwan,Frontiers in Neurology,2022 Jan,2022(12): | 2022 . 01 |
3 | (Cheng-Loong Liang)、(Han-Jung Chen)、(Yi-Che Lee)、(Cheng-Chun Wu)、蔡崇豪(Chon-Haw Tsai)、(Po-Lin Chen)、(Wei-Lun Chang)、(Po-Yen Yeh)、(Cheng-Yu Wei)、蔡銘駿(Ming-Jun Tsai)、(Yu Sun)、(Chih-Hao Lin)、(Jiunn-Tay Lee)、(Ta-Chang Lai)、(Li-Ming Lien)、林美辰(Mei-Chen Lin)、林橙莉(Cheng-Li Lin)、(Hao-Kuang Wang)*、許重義(Chung Y. Hsu),Smoking Status and Functional Outcomes in Young stroke,Frontiers in Neurology,2021 Sep,2021(12): | 2021 . 09 |
4 | (G.R. Nirmal)、(Zih-Chan Lin)、蔡銘駿(Ming-Jun Tsai)、(Shih-Chun Yang)、(Ahmed Alalaiwe)、(Jia-You Fang)*,Photothermal treatment by PLGA-gold nanorod-isatin nanocomplexes under near-infrared irradiation for alleviating psoriasiform hyperproliferation,JOURNAL OF CONTROLLED RELEASE,2021 Apr,333(2021):487-499 | 2021 . 04 |
5 | (Ting-Yu Chen)、蔡銘駿(Ming-Jun Tsai)、(Li-Ching Chang)*、(Pao-Chu Wu)*,Co-delivery of cisplatin and gemcitabine via viscous nanoemulsion for potential synergistic intravesical chemotherapy,Pharmaceutics,2020 Oct,12(10):949 | 2020 . 10 |
6 | (Ting-Yu Chen)、蔡銘駿(Ming-Jun Tsai)、(I-Ling Lin)、(Li-Ching Chang)*、(Pao-Chu Wu)*,Gel-Based Nanocarrier for intravesical chemotherapy delivery: In Vitro and In Vivo study,Pharmaceuticals,2020 Oct,13(11):329 | 2020 . 10 |
7 | (Yu-Hsiang Lin)、蔡銘駿(Tsai, Ming-Jun)、(Yi-Ping Fang)、(Yaw-Syan Fu)、(Yaw-Bin Huang)、(Pao-Chu Wu)*,Microemulsion formulation design and evaluation for hydrophobic compound: Catechin topical application,COLLOIDS AND SURFACES B-BIOINTERFACES,2017 Oct,161(2018):121-128 | 2017 . 10 |
8 | (Chih-Hung Chuang)、(Pao-Chu Wu)、(Teng-Huang Tsai)、(Yi-Ping Fang)、(Yi-Hung Tsai)、(Ta-Chun Cheng)、(Chien-Chaio Huang)、(Ming-Yii Huang)、(Fang-Ming Chen)、(Yuan-Chin Hsieh)、(Wen-Wei Lin)、蔡銘駿(Tsai, Ming-Jun)*、(Tian-Lu Cheng)*,development of pH-Sensitive Cationic PEGylated Solid Lipid Nanoparticles for Selective Cancer-Targeted Therapy,Journal of Biomedical Nanotechnology,2017 Jan,13():1-12 | 2017 . 01 |
9 | 蔡銘駿(Ming-Jun Tsai)、(I-Ju Lu)、(Yaw-Syan Fu)、(Yi-Ping Fang)、(Yaw-Bin Huang)、(Pao-Chu Wu)*,Nanocarriers enhance the transdermal bioavailability of resveratrol: In-vitro and in-vivo study,COLLOIDS AND SURFACES B-BIOINTERFACES,2016 Sep,148(2016):650-656 | 2016 . 09 |
10 | 蔡銘駿(Ming-Jun Tsai)、(Ming-Wei Lin)、(Waw-Bin Huang)、(Yu-Min Kuo)*、(Yi-Hung Tsai)*,The influence of acute hyperglycemia in an animal model of lacunar stroke that is induced by artificial particle embolization,International Journal of Medical Sciences,2016 Apr,13(5):347-356 | 2016 . 04 |
11 | (Yi-Ping Fang)、(Chih-Hung Chuang)、(Pao-Chu Wu)、(Yaw-Bin Huang)、(Cherng-Chyi Tzeng)、(Yeh-Long Chen)、(Ya-Ting Liu)、(Yi-Hung Tsai)、蔡銘駿(Ming-Jun Tsai)*,Amsacrine analog-loaded solid lipid nanoparticle to resolve insolubility for injection delivery: characterization and pharmacokinetics,Drug Design Development and Therapy,2016 Mar,10():1019-1028 | 2016 . 03 |
12 | 蔡銘駿(Ming-Jun Tsai)、(Chung-Yu Chen)、(Yaw-Bin Huang)、(Hsiao-Chung Chao)、(Chih-Jen Yang)、(Pei-Jin Lin)、(Yi-Hung Tsai)*,Long-acting inhaled bronchodilator and risk of vascular events in patients with chronic obstructive pulmonary disease in Taiwan population,MEDICINE,2015 Dec,94(51):1-7 | 2015 . 12 |
13 | 蔡銘駿(Ming-Jun Tsai)、(Yaw-Bin Huang)、(Jhih-Wun Fang)、(Yaw-Syan Fu)、(Pao-Chu Wu)*,Preparation and Characterization of Naringenin-loaded Elastic Liposomes for Topical Application,PLoS One,2015 Jul,10(7):):e0131026 | 2015 . 07 |
14 | 蔡銘駿(Ming-Jun Tsai)、(Yaw-Bin Huang)、(Jhih-Wun Fang)、(Yaw-Syan Fu)、(Pao-Chu Wu)*,preparation and evaluation of submicron-carriers for naringenin topical application,INTERNATIONAL JOURNAL OF PHARMACEUTICS,2015 Jan,481(2015):84-90 | 2015 . 01 |
15 | 蔡銘駿(Ming-Jun Tsai)、(Yaw-Syan Fu)、(Yu-Hsuan Lin)、(Yaw-Bin Huang)、(Pao-Chu Wu)*,The effect of nanoemulsion as a carrier of hydrophilic compound for transdermal delivery,PLoS One,2014 Jul,9(7):e102850-e102850 | 2014 . 07 |
16 | 蔡銘駿(Ming-Jun Tsai)、(Yi-Hung Tsai)*、(Yu-Min Kuo)*,Transient ischemic attack induced by melted solid lipid microparticles protects rat brains from permanent focal ischemia,NEUROSCIENCE,2014 Jun,275(2014):136-145 | 2014 . 06 |
17 | 黃繼德(Chi-Te Huang)、蔡銘駿(Ming-Jun Tsai)、(Yu-Hsuan Lin)、傅耀賢(Yaw-Sya Fu)、黃耀斌(Yaw-Bin Huang)、蔡義弘(Yi-Hung Tsai)、吳寶珠(Pa-Chu Wu)*,Effect of microemulsions on transdermal delivery of citalopram: optimization studies using mixture design and response surface methodology,International Journal of Nanomedicine,2013 Jun,2013(8):2295-2304 | 2013 . 06 |
18 | 方逸萍(Yi-Ping Fang)、吳寶珠(Pao-Chu Wu)、黃耀斌(Yaw-Bin Huang)、曾誠齊(Cherng-Chyi Tzeng)、陳義龍(Yeh-Long Chen)、洪瑜涵(Yu-Han Hung)、蔡銘駿(Ming-Jun Tsai)*、蔡義弘(Yi-Hung Tsai)*,Modification of polyethylene glycol onto solid lipid nanoparticles encapsulating a novel chemotherapeutic agent (PK-L4) to enhance solubility for injection delivery,International Journal of Nanomedicine,2012 Sep,7():4995-5005 | 2012 . 09 |
19 | 蔡銘駿(Ming-Jun Tsai)、吳寶珠(Pao-Chu Wu)、黃耀斌(Yaw-Bin Huang)、張瑞昇(Jui-Sheng Chang)、林金霖(Chin-Lin Lin)、蔡義弘(Yi-Hung Tsai)*、方嘉佑(Jia-You Fang)*,Baicalein loaded in tocol nanostructured lipid carriers (tocol NLCs) for enhanced stability and brain targeting,INTERNATIONAL JOURNAL OF PHARMACEUTICS,2012 ,423(2012):461-470 | 2012 . |
20 | 蔡銘駿(Ming-Jun Tsai)、黃耀斌(Yaw-Bin Huang)、吳寶珠(Pao-Chu Wu)、傅耀賢(Yaw-Syan Fu)、高耀仁(Yao-Ren Kao)、方嘉佑(Jia-You Fang)*、蔡義弘(Yi-Hung Tsai)*,Oral apomorphine delivery from solid lipid nanoparticles with different monostearate emulsifiers: Pharmacokinetic and behavioral evaluations,JOURNAL OF PHARMACEUTICAL SCIENCES,2011 Feb,100(2):547-557 | 2011 . 02 |
21 | 蔡銘駿(Ming-Jun Tsai)、蔡義弘(Yi-Hung Tsai)*、郭余民(Yu-Min Kuo)*,Characterization of the pattern of ischemic stroke induced by artificial particle embolization in the rat brain,BIOMATERIALS,2011 ,32(2011):6381-6388 | 2011 . |
22 | (Yaw-Bin Huang)*、蔡銘駿(Ming-Jun Tsai)、吳寶珠(Pao-Chu Wu)、蔡義弘(Yi-Hung Tsai)、吳怡欣(Yi-Hsin Wu)、方嘉佑(Jia-You Fang)*,Elastic liposomes as carriers for oral delivery and the brain distribution of (+)-catechin,JOURNAL OF DRUG TARGETING,2011 ,19(8):709-718 | 2011 . |
研討會論文
研討會論文/Conference Papers (發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目) |
日期 | |
1 | 中國醫藥大學附設安南醫院急性腦中風動脈取栓術後症狀性腦出血危險因子 分析,2021 Asian Oceanian Congress of Neurology (AOCN),Taipei International Convention Center (TICC),2021.04.1 ~2021.04.4 , | 2021 . 04 |
2 | 腦血管疾病學中國醫藥大學附設安南醫院急性腦中風動脈取栓術 一年經驗分享,2021 Asian Oceanian Congress of Neurology (AOCN),Taipei International Convention Center (TICC),2021.04.1 ~2021.04.4 , | 2021 . 04 |
3 | Risk factor analysis of symptomatic brain hemorrhage after Intra-arterial thrombectomy for acute ischemic stroke in An Nan hospital, China Medical University,2020AMTNS(Annual Meeting of Taiwan Neurological Society),高雄醫學大學國際學術研究大樓B2,2020.12.19~2020.12.20, | 2020 . 12 |
4 | One year experience of Intra-arterial thrombectomy for acute ischemic stroke in An Nan hospital, China Medical University,2020AMTNS(Annual Meeting of Taiwan Neurological Society,高雄醫學大學國際學術研究大樓B2,2020.12.19~2020.12.20, | 2020 . 12 |
5 | The predicting factor analysis of good prognosis immediately after mechanical thrombectomy in An Nan Hospital, China Medical University,台灣腦中風學會2020學術研討會,國防醫學院,2020.11.27~2020.11.29, | 2020 . 11 |
6 | Report premarket study of florbetaben 18F injection PET scan for detecting β-amyloid deposition in two normal old persons with strong family history of dementia in Taiwan,第三屆台灣國際神經醫學大會暨2019年台灣神經學學會年會,Taipei International Convention Center, Taipei, Taiwan,2019.05.03~2019.05.05, | 2019 . 05 |
7 | ,2nd international conference and exhibition on nanomedicine and drug delivery,Tokyo, Japan,2018.05.21~2018.05.23,Rosiglitazone loaded in nanoliposome carriers for enhanced bioavailability and brain targeting for ischemic stroke | 2018 . 05 |
8 | Case report: a case of left temperal ganglioma manifested as reversible left sigmoid and transverse venous sinus thrombosis,2018annual meeting of taiwan neurological society,Tainan, Taiwan,2018.05.05~2018.05.06, | 2018 . 05 |
9 | Rosiglitazone loaded in solid lipid nanoparticle for enhanced bioavailability and brain targeting against ischemic brain injury,The 2nd International Taiwanese Congress of Neurology & Annual Meeting of Taiwan Neurological Society (2nd ITCN 2017 AMTNS),TICC台北國際會議中心,2017.05.19~2017.05.21, | 2017 . 05 |
10 | ,Nanomedicine and nanotechnology in health care,Avani Atrium, Bangkok, Thailand,2016.07.25~2016.07.27,Development of temperature-sensitive PEGylated nanostructured lipid carrier for co-delivery of gemcitabine and Baicalein against A549 cell line | 2016 . 07 |
11 | Case report: a case of progressive mixed type of sensorimotor polyneuropathy associated with cytomegalovirus infection-experience of treatment and prognosis,2016神經醫學聯合學術研討會,中國醫藥大學立夫教學大樓,2016.04.09~2016.04.10, | 2016 . 04 |
12 | The analysis of the association between sudden onset sleep syndrome and dopamine receptor agonist in The World Health Organization's International adverse reaction database,2016神經醫學聯合學術研討會,中國醫藥大學立夫教學大樓,2016.04.09~2016.04.10, | 2016 . 04 |
13 | Case report:a case of spinal arteriovenous malformation (AVM) manifested as progressive conus medullaris syndrome,2016神經醫學聯合學術研討會,中國醫藥大學立夫教學大樓,2016.04.09~2016.04.10, | 2016 . 04 |
14 | Case report: a cse of SSPE manifested as bilateral occipital leukoencephalopathy similar to pres,The first international taiwanese congress of neurology (1st ITCN) and 2015 AMTNS,Taipei international convention center,2015.05.07~2015.05.10, | 2015 . 05 |
15 | A case of chronic pachymeningitis manifested as progressive cerebellar ataxia,The first international taiwanese congress of neurology (1st ITCN) and 2015 AMTNS,Taipei international convention center,2015.05.07~2015.05.10, | 2015 . 05 |
16 | Enhancement anticancer effect of Gemcitabine and Kaempferol using multifunctional nanostructured lipid carriers (NLCs) on A549 cell line,ANGEL2014 3rd conference on advanced nanoparticle generation and excitation by lasers in liquids,Hotel JAL City, Matsusyama, Japan,2014.05.19~2014.05.21, | 2014 . 05 |
17 | Plasmaphoresis in a young man with subacute onset of myeloneuropathy: Report a case,5th East Asia Neurology Forum/19th Taiwan Neurological Society Congress,高雄醫學大學國際學術研究大樓,2014.04.11~2014.04.13, | 2014 . 04 |
18 | Enhanced Anticancer Activity Of Doxorubicin By Multi-Functional Liposomes,Pan Pacific Symposium on Stem Cells and Cancer Research,The Splendor Hotel Taichung,2014.04.12~2014.04.14, | 2014 . 04 |
19 | ,Pan Pacific Symposium on stem cells and cancer research,The Splendor Hotel Taichung,2014.04.12~2014.04.13,International Trends of the Regulations in Development of Medical Devices and Drugs | 2014 . 04 |
20 | Brain MRI in the animal model of embolic stroke induced by solid lipid nanoparticle,5th East Asia Neurology Forum/19th Taiwan Neurological Society Congress,高雄醫學大學國際學術研究大樓,2014.04.11~2014.04.13, | 2014 . 04 |
21 | Pseudotumor cerebri as a first manifestation of metastatic adenocarcinoma of the lung,2013神經醫學聯合國際學術研討會,台北國防醫學中心三樓,2013.04.13~2013.04.14, | 2013 . 04 |
22 | 案例報告: 神經貝賽特氏病症─影像及病理發現 Diffuse MRI: Apparent Diffusion Coefficient and Pathologic Findings in a Case of Neuro-Behçet's Disease,2013 神經醫學聯合國際學術研討會,國防醫學院,2013.04.12~2013.04.14, | 2013 . 04 |
23 | Diffuse MRI: Apparent Diffusion Coefficient and Pathologic Findings in a Case of Neuro-Behçet's Disease,2013神經醫學聯合國際學術研討會,台北國防醫學中心三樓,2013.04.13~2013.04.14, | 2013 . 04 |
24 | Pseudotumor cerebri as a first manifestation of metastatic adenocarcinoma of the lung,2013 神經醫學聯合國際學術研討會,國防醫學院三樓,2013.04.13~2013.04.14, | 2013 . 04 |
25 | Case Report : Protein S deficiency and pregnant woman with ischemic stroke,2013神經醫學聯合國際學術研討會,台北國防醫學中心三樓,2013.04.13~2013.04.14, | 2013 . 04 |
26 | 慢性阻塞性肺病合併使用長效性抗膽鹼製劑及長效型乙型致效劑之中風發生率之探討-以台灣健保資料庫分析之回溯性世代研究,台灣腦中風學會101年度學術研討會,新北市政府五樓會議室,2012.10.27~2012.10.28, | 2012 . 10 |
27 | Enhancement anticancer effect of Baicalen and Gemcitabine using multifunctinal solid lipid nanoparticle on A549 cell lines,39th Annual meeting & exposition of the xontrolled release society,Centre des congrès de Québec, Canada,2012.07.15~2012.07.18, | 2012 . 07 |
28 | ,國內外醫療器材及技術之臨床試驗醫事人員培訓研討會,張榮發基金會國際會議中心10樓1008室,2011.10.15~2011.10.15,Current act on medical device clinical investigation polices in Chinese Taipei | 2011 . 10 |
29 | ,2010 AHC Workshop on Medical Devices- Use of Clinical Evidence in the Medical Device Premarket Confo,The Ritz-Carlton Hotel Grand Ballroom,2010.11.15~2010.11.16,Clinical Investigation Polices in Chinese Taipei | 2010 . 11 |
30 | ,2010 AHC Workshop on Medical Devices,The Ritz-Carlton Hotel Grand Ballroom,2010.11.15~2010.11.16,Difference between clinical evidence of medical device and pharmaceuticals from regulatory respectives | 2010 . 11 |
31 | Pharmacovigilance in Taiwan,The 45th DIA annual meeting,San Diego Convention Center, 111 Harbor Drive, San Diego, CA92101, in San Diego, California, USA,2009.06.21~2009.06.25,Recent Advancement of Risk Management in the Asian Pacific Region | 2009 . 06 |
專書
暫無資料研究計畫
研究計畫/Research Grant (研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,計畫期間) |
日期 | |
1 | 個別型,MOST 111-2320-B-039-059,鄭竣亦、(周秉松)、鄭維中(Cheng, Wei-Chung)、馬文隆(Wen-Lung Ma)、蔡銘駿(Ming-Jun Tsai)、楊顓丞(Juan-Cheng Yang),科技部,透過天然產物調節脂質和氨基酸代謝用於減輕阿茲海默症(3/3),2022.8.1~2023.7.31 | 2022 . 08 |
2 | 個別型,MOST 110-2320-B-039-069,鄭竣亦、周秉松、鄭維中(Cheng, Wei-Chung)、馬文隆(Wen-Lung Ma)、蔡銘駿(Ming-Jun Tsai)、楊顓丞(Juan-Cheng Yang),科技部,透過天然產物調節脂質和氨基酸代謝用於減輕阿茲海默症(2/3),2021.8.1~2022.7.31 | 2021 . 08 |
3 | 個別型,ANHRF109-14,(Yi-Hung Tsai),附醫院內計畫,評估及發展經包埋奈米化之左旋多巴(levodopa)合併多巴胺(dopamine)最適劑型中樞神經特定腦區輸送於晚期巴金森氏病治療,2020.9.1~2021.8.31 | 2020 . 09 |
4 | 個別型,MOST 109-2320-B-039-028,鄭竣亦、周秉松、鄭維中(Cheng, Wei-Chung)、馬文隆(Wen-Lung Ma)、蔡銘駿(Ming-Jun Tsai)、楊顓丞(Juan-Cheng Yang),科技部,透過天然產物調節脂質和氨基酸代謝用於減輕阿茲海默症(1/3),2020.8.1~2021.7.31 | 2020 . 08 |
5 | 個別型,MOST 106-2320-B-039-010-,(Tasi, Yi-Hung),科技部,評估及發展pioglitazone中樞神經輸送之最適化劑型在不同腦區受損之神經疾病,2017.8.1~2018.7.31 | 2017 . 08 |
6 | 個別型,MOST 104-2320-B-039-044,蔡義弘(Yi-Hung Tsai),科技部,研發Rosiglitazone奈米顆粒輸送系統應用於缺血性腦中風之治療評估,2015.8.1~2016.7.31 | 2015 . 08 |
7 | 個別型,ANHRF103-8,蔡義弘(Yi-Hung Tsai),中國醫藥大學附設安南醫院院內研究計畫,合併包埋Gemcitabine 和 Baicalein 之多功能奈米固脂粒之細胞藥動學、生物藥動學、組織分佈及對A549之抗癌活性增加之研究,2014.6.12~2015.12.31 | 2014 . 06 |
8 | 個別型,NSC 102-2314-B-039-018,蔡義弘(Yi-Hung Tsai),科技部,以新穎性可逆性缺血性神經功能缺損腦中風模式及短暫性缺血性腦中風模式評估非麩氨酸相關路徑(non-glutamate dependent mechanism)(如TRPM7) 在缺血性腦中風之角色及影響,2013.8.1~2014.7.31 | 2013 . 08 |
9 | 個別型,NSC101-2320-B-037-034,蔡銘駿(Ming-Jun Tsai),科技部,開發通過血腦障壁之標靶多功能奈米載體以增加局部大腦缺血傷害之診斷及藥物療效-延續計畫:以新穎性可逆性缺血性神經功能缺損之腦中風模式評估標把多功能奈米載體通過血腦障壁之藥物療效,2012.8.1~2013.7.31 | 2012 . 08 |
10 | 個別型,NSC100-2320-B-037-006,蔡銘駿(Ming-Jun Tsai),科技部,開發通過血腦障壁之標靶多功能奈米載體以增加局部大腦缺血傷害之診斷及藥物療效,2011.8.1~2012.10.31 | 2011 . 08 |
11 | 個別型,DMR-102-099,,附醫院內計畫,以新穎性人工血栓所引致缺血性腦中風大鼠動物模式探討血腦障壁之破壞與抗凝血劑所致嚴重腦出血之相關性,2011.8.1~2012.6.30 | 2011 . 08 |
專利技術
暫無資料獲獎事蹟
獲獎/Award (獲獎名稱,給獎單位,獲獎日期) |
日期 | |
1 | 中醫大附設安南醫院腦中風急性照護團隊獲獎,本校(含附醫),2018.1.25 | 2018 . 01 |
2 | 臺南市安南醫院「105年優良臨床教師獎」,本校(含附醫),2017.1.10 | 2017 . 01 |
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